1. 2014
  2. Published

    Genome-Wide Computational Analysis Reveals Cardiomyocyte-Specific Transcriptional CIS-Regulatory Motifs that Enable Efficient Cardiac Gene Therapy

    Rincon, M. Y., Sarcar, S., Danso-Abeam, D., Keyaerts, M., Matrai, J., Samara-Kuko, E., Acosta-Sanchez, A., Athanasopoulos, T., Dickson, G., Lahoutte, T., De Bleser, P., VandenDriessche, T. & Chuah, M. K. 8 Sep 2014 In : Molecular Therapy.

    Research output: Contribution to journalArticle

  3. Published

    Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease

    Lu-Nguyen, N. B., Broadstock, M., Schliesser, M. G., Bartholomae, C., von Kalle, C., Schmidt, M. & Yáñez-Muñoz, R. J. 18 Mar 2014 In : Human Gene Therapy.

    Research output: Contribution to journalArticle

  4. Published

    Long-term episomal transgene expression from mitotically stable integration-deficient lentiviral vectors (IDLVs)

    Kymalainen, H., Appelt, J-U., Giordano, F. A., Davies, A. F., Ogilvie, C. M., Ahmed, S. G., Laufs, S., Schmidt, M., Bode, J., Yáñez-Muñoz, R. J. & Dickson, G. 2 Feb 2014 In : Human Gene Therapy.

    Research output: Contribution to journalArticle

  5. Published

    New developments in the use of gene therapy to treat Duchenne muscular dystrophy

    Jarmin, S., Kymalainen, H., Popplewell, L. & Dickson, G. Feb 2014 In : Expert Opinion on Biological Therapy. 14, 2, p. 209-30 22 p.

    Research output: Contribution to journalArticle

  6. Published

    Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid

    Chang, P., Walker, M. C. & Williams, R. Feb 2014 In : Neurobiology of disease. 62, p. 296–306

    Research output: Contribution to journalArticle

  7. Published
  8. Published

    Local Overexpression of the Myostatin Propeptide Increases Glucose Transporter Expression and Enhances Skeletal Muscle Glucose Disposal

    Cleasby, M. E., Jarmin, S., Eilers, W., Elashry, M., Andersen, D. K., Dickson, G. & Foster, K. 28 Jan 2014 In : American journal of physiology. Endocrinology and metabolism.

    Research output: Contribution to journalArticle

  9. In preparation

    A new therapeutic mechanism for the MCT ketogenic diet in seizure control through AMPA receptor inhibition

    Chang, P., Augustin, K., Boddum, K., Sun, M., Terschak, J., Hardege, J., Chen, P., Walker, M. & Williams, R. 2014 In : Science translational medicine.

    Research output: Contribution to journalArticle

  10. Published

    A southern blot protocol to detect chimeric nuclease-mediated gene repair

    Rocca, C. J., Abdul-Razak, H. H., Holmes, M. C., Gregory, P. D. & Yáñez-Muñoz, R. J. 2014 In : Methods in Molecular Biology. 1114, p. 325-38 14 p.

    Research output: Contribution to journalArticle

  11. Published
  12. Published
  13. Published

    Fusion of Ubiquitin to HIV Gag Impairs Human Monocyte-Derived Dendritic Cell Maturation and Reduces Ability to Induce Gag T Cell Responses

    Herath, S., Benlahrech, A., Papagatsias, T., Athanasopoulos, T., Bouzeboudjen, Z., Hervouet, C., Klavinskis, L., Meiser, A., Kelleher, P., Dickson, G. & Patterson, S. 2014 In : PLoS One. 9, 2, p. e88327

    Research output: Contribution to journalArticle

  14. Published

    Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

    Bartus, K., James, N. D., Didangelos, A., Bosch, K. D., Verhaagen, J., Yáñez (or Yáñez-Muñoz), R. J., Rogers, J. H., Schneider, B. L., Muir, E. M. & Bradbury, E. J. 2014 In : The Journal of Neuroscience. 34, 14, p. 4822– 4836

    Research output: Contribution to journalArticle

  15. Published

    Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitors

    Patel, H., Chuckowree, I., Coxhead, P., Guille, M., Wang, M., Zuckermann, A., Williams, R., Librizzi, M., Paranal, R. M., Bradner, J. E. & Spencer, J. 2014 In : Medicinal Chemistry Communications. 5 p.

    Research output: Contribution to journalArticle

  16. 2013
  17. Published

    Lentiviral Vector-Mediated RNA Silencing in the Central Nervous System

    Hutson, T. H., Foster, E., Moon, L. D. F. & Yáñez-Muñoz, R. J. 1 Nov 2013 In : Human Gene Therapy. Methods.

    Research output: Contribution to journalArticle

  18. Published

    Transgene delivery to endothelial cultures derived from porcine carotid artery ex vivo

    Andoh, J., Sawyer, B., Szewczyk, K., Nortley, M., Rossetti, T., Loftus, I. M., Yáñez-Muñoz, R. J. & Hainsworth, A. H. Oct 2013 In : Translational Stroke Research. 4, 5, p. 507-14 8 p.

    Research output: Contribution to journalArticle

  19. Published

    Gene correction of a duchenne muscular dystrophy mutation by meganuclease-enhanced exon knock-in

    Popplewell, L., Koo, T., Leclerc, X., Duclert, A., Mamchaoui, K., Gouble, A., Mouly, V., Voit, T., Pâques, F., Cédrone, F., Isman, O., Yáñez (or Yáñez-Muñoz), R. J. & Dickson, G. Jul 2013 In : Human Gene Therapy. 24, 7, p. 692-701 10 p.

    Research output: Contribution to journalArticle

  20. Published

    Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord

    Peluffo, H., Foster, E., Ahmed, S. G., Lago, N., Hutson, T. H., Moon, L., Yip, P., Wanisch, K., Caraballo-Miralles, V., Olmos, G., Lladó, J., McMahon, S. B. & Yáñez-Muñoz, R. J. Jun 2013 In : Gene Therapy. 20, p. 645-657

    Research output: Contribution to journalArticle

  21. Published

    Functional characterization of Clostridium difficile spore coat proteins

    Permpoonpattana, P., Phetcharaburanin, J., Mikelsone, A., Dembek, M., Tan, S., Brisson, M-C., La Ragione, R., Brisson, A. R., Fairweather, N., Hong, H. A. & Cutting, S. M. 1 Apr 2013 In : Journal of Bacteriology. 195, 7, p. 1492-1503 12 p.

    Research output: Contribution to journalArticle

  22. Published

    Elevated Transcription of the Gene QSOX1 Encoding Quiescin Q6 Sulfhydryl Oxidase 1 in Breast Cancer

    Soloviev, M., Esteves, M. P., Amiri, F., Crompton, M. R. & Rider, C. 27 Feb 2013 In : PLoS One. 8, 2, e57327

    Research output: Contribution to journalArticle

  23. Published
  24. Published

    Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases

    Dickson, J. G. & 50 others Tremblay, J. P., Xiao, X., Aartsma-Rus, A., Barbas, C., Blau, H. M., Bogdanove, A. J., Boycott, K., Braun, S., Breakefield, X. O., Bueren, J. A., Buschmann, M., Byrne, B. J., Calos, M., Cathomen, T., Chamberlain, J., Chuah, M., Cornetta, K., Davies, K. E., Duchateau, P., Flotte, T. R., Gaudet, D., Gersbach, C. A., Gilbert, R., Glorioso, J., Herzog, R. W., High, K. A., Huang, W., Huard, J., Joung, J. K., Liu, D., Liu, D., Lochmüller, H., Lustig, L., Martens, J., Massie, B., Mavilio, F., Mendell, J. R., Nathwani, A., Ponder, K., Porteus, M., Puymirat, J., Samulski, J., Takeda, S., Thrasher, A., VandenDriessche, T., Wei, Y., Wilson, J. M., Wilton, S. D., Wolfe, J. H. & Gao, G. Feb 2013 In : Molecular Therapy. 21, 2, p. 266-8 3 p.

    Research output: Contribution to journalArticle

  25. Published

    Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung

    Yates, L. L., Schnatwinkel, C., Hazelwood, L., Chessum, L., Paudyal, A., Hilton, H., Romero, M. R., Wilde, J., Bogani, D., Sanderson, J., Formstone, C., Murdoch, J. N., Niswander, L. A., Greenfield, A. & Dean, C. H. 15 Jan 2013 In : Developmental Biology. 373, 2, p. 267-280 14 p.

    Research output: Contribution to journalArticle

  26. Published

    A novel human receptor involved in bitter tastant detection identified using the model organism Dictyostelium discoideum

    Robery, S., Tyson, R., Dinh, C., Kuspa, A., Noegel, A., Bretschneider, T., Andrews, P. L. R. & Williams, R. S. B. 2013 In : Journal of Cell Science.

    Research output: Contribution to journalArticle

  27. Published

    Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays

    Bachy, V., Hervouet, C., Becker, P. D., Chorro, L., Carlin, L. M., Herath, S., Papagatsias, T., Barbaroux, J-B., Oh, S-J., Benlahrech, A., Athanasopoulos, T., Dickson, G., Patterson, S., Kwon, S-Y., Geissmann, F. & Klavinskis, L. S. 2013 In : Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalArticle

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