1. 2014
  2. Published

    Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice

    Murdoch, J. N., Damrau, C., Paudyal, A., Bogani, D., Wells, S., Greene, N. D. E., Stanier, P. & Copp, A. J. Oct 2014 In : Disease Models and Mechanisms. 7, 10, p. 1153-63 11 p.

    Research output: Contribution to journalArticle

  3. Published

    Genome-Wide Computational Analysis Reveals Cardiomyocyte-Specific Transcriptional CIS-Regulatory Motifs that Enable Efficient Cardiac Gene Therapy

    Rincon, M. Y., Sarcar, S., Danso-Abeam, D., Keyaerts, M., Matrai, J., Samara-Kuko, E., Acosta-Sanchez, A., Athanasopoulos, T., Dickson, G., Lahoutte, T., De Bleser, P., VandenDriessche, T. & Chuah, M. K. 8 Sep 2014 In : Molecular Therapy.

    Research output: Contribution to journalArticle

  4. Published

    Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease

    Lu-Nguyen, N. B., Broadstock, M., Schliesser, M. G., Bartholomae, C., von Kalle, C., Schmidt, M. & Yáñez-Muñoz, R. J. 18 Mar 2014 In : Human Gene Therapy.

    Research output: Contribution to journalArticle

  5. Published

    Long-term episomal transgene expression from mitotically stable integration-deficient lentiviral vectors (IDLVs)

    Kymalainen, H., Appelt, J-U., Giordano, F. A., Davies, A. F., Ogilvie, C. M., Ahmed, S. G., Laufs, S., Schmidt, M., Bode, J., Yáñez-Muñoz, R. J. & Dickson, G. 2 Feb 2014 In : Human Gene Therapy.

    Research output: Contribution to journalArticle

  6. Published

    New developments in the use of gene therapy to treat Duchenne muscular dystrophy

    Jarmin, S., Kymalainen, H., Popplewell, L. & Dickson, G. Feb 2014 In : Expert Opinion on Biological Therapy. 14, 2, p. 209-30 22 p.

    Research output: Contribution to journalArticle

  7. Published

    Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid

    Chang, P., Walker, M. C. & Williams, R. Feb 2014 In : Neurobiology of disease. 62, p. 296–306

    Research output: Contribution to journalArticle

  8. Published
  9. Published

    Local Overexpression of the Myostatin Propeptide Increases Glucose Transporter Expression and Enhances Skeletal Muscle Glucose Disposal

    Cleasby, M. E., Jarmin, S., Eilers, W., Elashry, M., Andersen, D. K., Dickson, G. & Foster, K. 28 Jan 2014 In : American journal of physiology. Endocrinology and metabolism.

    Research output: Contribution to journalArticle

  10. In preparation

    A new therapeutic mechanism for the MCT ketogenic diet in seizure control through AMPA receptor inhibition

    Chang, P., Augustin, K., Boddum, K., Sun, M., Terschak, J., Hardege, J., Chen, P., Walker, M. & Williams, R. 2014 In : Science translational medicine.

    Research output: Contribution to journalArticle

  11. Published

    A southern blot protocol to detect chimeric nuclease-mediated gene repair

    Rocca, C. J., Abdul-Razak, H. H., Holmes, M. C., Gregory, P. D. & Yáñez-Muñoz, R. J. 2014 In : Methods in Molecular Biology. 1114, p. 325-38 14 p.

    Research output: Contribution to journalArticle

  12. Published
  13. Published
  14. Published

    Fusion of Ubiquitin to HIV Gag Impairs Human Monocyte-Derived Dendritic Cell Maturation and Reduces Ability to Induce Gag T Cell Responses

    Herath, S., Benlahrech, A., Papagatsias, T., Athanasopoulos, T., Bouzeboudjen, Z., Hervouet, C., Klavinskis, L., Meiser, A., Kelleher, P., Dickson, G. & Patterson, S. 2014 In : PLoS One. 9, 2, p. e88327

    Research output: Contribution to journalArticle

  15. Published

    Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

    Bartus, K., James, N. D., Didangelos, A., Bosch, K. D., Verhaagen, J., Yáñez (or Yáñez-Muñoz), R. J., Rogers, J. H., Schneider, B. L., Muir, E. M. & Bradbury, E. J. 2014 In : The Journal of Neuroscience. 34, 14, p. 4822– 4836

    Research output: Contribution to journalArticle

  16. Published

    Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitors

    Patel, H., Chuckowree, I., Coxhead, P., Guille, M., Wang, M., Zuckermann, A., Williams, R., Librizzi, M., Paranal, R. M., Bradner, J. E. & Spencer, J. 2014 In : Medicinal Chemistry Communications. 5 p.

    Research output: Contribution to journalArticle

  17. 2013
  18. Published

    Lentiviral Vector-Mediated RNA Silencing in the Central Nervous System

    Hutson, T. H., Foster, E., Moon, L. D. F. & Yáñez-Muñoz, R. J. 1 Nov 2013 In : Human Gene Therapy. Methods.

    Research output: Contribution to journalArticle

  19. Published

    Transgene delivery to endothelial cultures derived from porcine carotid artery ex vivo

    Andoh, J., Sawyer, B., Szewczyk, K., Nortley, M., Rossetti, T., Loftus, I. M., Yáñez-Muñoz, R. J. & Hainsworth, A. H. Oct 2013 In : Translational Stroke Research. 4, 5, p. 507-14 8 p.

    Research output: Contribution to journalArticle

  20. Published

    Gene correction of a duchenne muscular dystrophy mutation by meganuclease-enhanced exon knock-in

    Popplewell, L., Koo, T., Leclerc, X., Duclert, A., Mamchaoui, K., Gouble, A., Mouly, V., Voit, T., Pâques, F., Cédrone, F., Isman, O., Yáñez (or Yáñez-Muñoz), R. J. & Dickson, G. Jul 2013 In : Human Gene Therapy. 24, 7, p. 692-701 10 p.

    Research output: Contribution to journalArticle

  21. Published

    Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord

    Peluffo, H., Foster, E., Ahmed, S. G., Lago, N., Hutson, T. H., Moon, L., Yip, P., Wanisch, K., Caraballo-Miralles, V., Olmos, G., Lladó, J., McMahon, S. B. & Yáñez-Muñoz, R. J. Jun 2013 In : Gene Therapy. 20, p. 645-657

    Research output: Contribution to journalArticle

  22. Published

    Functional characterization of Clostridium difficile spore coat proteins

    Permpoonpattana, P., Phetcharaburanin, J., Mikelsone, A., Dembek, M., Tan, S., Brisson, M-C., La Ragione, R., Brisson, A. R., Fairweather, N., Hong, H. A. & Cutting, S. M. 1 Apr 2013 In : Journal of Bacteriology. 195, 7, p. 1492-1503 12 p.

    Research output: Contribution to journalArticle

  23. Published

    Elevated Transcription of the Gene QSOX1 Encoding Quiescin Q6 Sulfhydryl Oxidase 1 in Breast Cancer

    Soloviev, M., Esteves, M. P., Amiri, F., Crompton, M. R. & Rider, C. 27 Feb 2013 In : PLoS One. 8, 2, e57327

    Research output: Contribution to journalArticle

  24. Published
  25. Published

    Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases

    Dickson, J. G. & 50 others Tremblay, J. P., Xiao, X., Aartsma-Rus, A., Barbas, C., Blau, H. M., Bogdanove, A. J., Boycott, K., Braun, S., Breakefield, X. O., Bueren, J. A., Buschmann, M., Byrne, B. J., Calos, M., Cathomen, T., Chamberlain, J., Chuah, M., Cornetta, K., Davies, K. E., Duchateau, P., Flotte, T. R., Gaudet, D., Gersbach, C. A., Gilbert, R., Glorioso, J., Herzog, R. W., High, K. A., Huang, W., Huard, J., Joung, J. K., Liu, D., Liu, D., Lochmüller, H., Lustig, L., Martens, J., Massie, B., Mavilio, F., Mendell, J. R., Nathwani, A., Ponder, K., Porteus, M., Puymirat, J., Samulski, J., Takeda, S., Thrasher, A., VandenDriessche, T., Wei, Y., Wilson, J. M., Wilton, S. D., Wolfe, J. H. & Gao, G. Feb 2013 In : Molecular Therapy. 21, 2, p. 266-8 3 p.

    Research output: Contribution to journalArticle

  26. Published

    Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung

    Yates, L. L., Schnatwinkel, C., Hazelwood, L., Chessum, L., Paudyal, A., Hilton, H., Romero, M. R., Wilde, J., Bogani, D., Sanderson, J., Formstone, C., Murdoch, J. N., Niswander, L. A., Greenfield, A. & Dean, C. H. 15 Jan 2013 In : Developmental Biology. 373, 2, p. 267-280 14 p.

    Research output: Contribution to journalArticle

  27. Published

    A novel human receptor involved in bitter tastant detection identified using the model organism Dictyostelium discoideum

    Robery, S., Tyson, R., Dinh, C., Kuspa, A., Noegel, A., Bretschneider, T., Andrews, P. L. R. & Williams, R. S. B. 2013 In : Journal of Cell Science.

    Research output: Contribution to journalArticle

  28. Published

    Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays

    Bachy, V., Hervouet, C., Becker, P. D., Chorro, L., Carlin, L. M., Herath, S., Papagatsias, T., Barbaroux, J-B., Oh, S-J., Benlahrech, A., Athanasopoulos, T., Dickson, G., Patterson, S., Kwon, S-Y., Geissmann, F. & Klavinskis, L. S. 2013 In : Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalArticle

  29. Published

    Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression

    Novorol, C., Burkhardt, J., Wood, K. J., Iqbal, A., Roque, C., Coutts, N., Almeida, A. D., He, J., Wilkinson, C. J. & Harris, W. A. 2013 In : Open biology. 3, 10, p. 130065

    Research output: Contribution to journalArticle

  30. Published

    Mucosal Vaccination against Tuberculosis Using Inert Bioparticles

    Reljic, R., Sibley, L., Huang, J-M., Pepponi, I., Hoppe, A., Huynh, H. & Cutting, S. M. 2013 In : Infection and Immunity. 81, 11, p. 4071-4080

    Research output: Contribution to journalArticle

  31. Forthcoming

    Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a polycystin-2 (TRPP2)-dependent manner

    Waheed, A., Ludtmann, M., Pakes, N., Robery, S., Kuspa, A., Dinh, C., Baines, D. L., Williams, R. & Carew, M. 2013 In : British Journal of Pharmacology.

    Research output: Contribution to journalArticle

  32. Published

    Nuclear entrapment and extracellular depletion of PCOLCE is associated with muscle degeneration in oculopharyngeal muscular dystrophy

    Raz, V., Sterrenburg, E., Routledge, S., Venema, A., van der Sluijs, B. M., Trollet, C., Dickson, G., van Engelen, B. G. M., van der Maarel, S. M. & Antoniou, M. N. 2013 In : BMC Neurology. 13, p. 70

    Research output: Contribution to journalArticle

  33. In preparation

    The ketogenic diet-associated fatty acid decanoic acid is a non-competitive antagonist of XXXX YYYYY receptors

    Walker, M., Williams, R., Chang, P., Boddum, K. & Chen, P. 2013 In : Nature Medicine.

    Research output: Contribution to journalArticle

  34. Forthcoming

    The search for better epilepsy treatments: from slime mould to coconuts

    Williams, R. & Walker, M. C. 2013 In : Biochemical Society Transactions. 41

    Research output: Contribution to journalScientific review

  35. Published

    Zizimin and Dock guanine nucleotide exchange factors in cell function and disease

    Pakes, N., Veltman, D. M. & Williams, R. 2013 In : Small GTPases. 4, 1, p. 1-6 6 p.

    Research output: Contribution to journalScientific review

  36. 2012
  37. Published

    Fragmentation of SIV-gag Vaccine Induces Broader T Cell Responses

    Benlahrech, A., Meiser, A., Herath, S., Papagatsias, T., Athanasopoulos, T., Li, F., Self, S., Bachy, V., Hervouet, C., Logan, K., Klavinskis, L., Dickson, G. & Patterson, S. 31 Oct 2012 In : PLoS One. 7, 10, 13 p.ARTN e48038

    Research output: Contribution to journalArticle

  38. Published

    Seizure control by ketogenic diet-associated medium chain fatty acids

    Chang, P., Terbach, N., Plant, N., Chen, P. E., Walker, M. C. & Williams, R. S. B. Jun 2012 In : Neuropharmacology. 69, p. 105-114

    Research output: Contribution to journalArticle

  39. Published

    The Rac GEF ZizB regulates development, cell motility and cytokinesis in Dictyostelium

    Pakes, N. K., Veltman, D. M., Rivero, F., Nasir, J., Insall, R. & Williams, R. S. B. 15 May 2012 In : Journal of Cell Science. 125, Pt 10, p. 2457-65 9 p.

    Research output: Contribution to journalArticle

  40. Published

    Highly potent delivery method of gp160 envelope vaccine combining lentivirus-like particles and DNA electrotransfer

    Vandermeulen, G., Athanasopoulos, T., Trundley, A., Foster, K., Préat, V., Yáñez-Muñoz, R. J. & Dickson, G. 10 May 2012 In : Journal of Controlled Release. 159, 3, p. 376–383

    Research output: Contribution to journalArticle

  41. Published

    Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds

    Elphick, L. M., Pawolleck, N., Guschina, I. A., Chaieb, L., Eikel, D., Nau, H., Harwood, J. L., Plant, N. J. & Williams, R. S. B. Mar 2012 In : Disease Models and Mechanisms. 5, 2, p. 231-240 10 p.

    Research output: Contribution to journalArticle

  42. Published

    Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector

    Hutson, T. H., Verhaagen, J., Yáñez-Muñoz, R. J. & Moon, L. D. F. Jan 2012 In : Gene Therapy. 19, 1, p. 49-60 12 p.

    Research output: Contribution to journalArticle

  43. Published

    AMP-Activated Protein Kinase (AMPK) - Dependent and -Independent Pathways Regulate Hypoxic Inhibition of Transepithelial Na(+) Transport Across Human Airway Epithelial Cells

    Tan, C. D., Smolenski, R. T., Harhun, M. I., Patel, H. K., Ahmed, S. G., Wanisch, K., Yáñez (or Yáñez-Muñoz) , R. J. & Baines, D. L. 2012 In : British Journal of Pharmacology.

    Research output: Contribution to journalArticle

  44. Published

    Amyloid-β Acts as a Regulator of Neurotransmitter Release Disrupting the Interaction between Synaptophysin and VAMP2

    Russell, C. L., Semerdjieva, S., Empson, R. M., Austen, B. M., Beesley, P. W. & Alifragis, P. 2012 In : PLoS One. 7, 8, p. e43201

    Research output: Contribution to journalArticle

  45. Published

    Assembly of protein building blocks using a short synthetic peptide

    Ferrari, E., Soloviev, M., Niranjan, D., Arsenault, J., Gu, C., Vallis, Y., O'Brien, J. & Davletov, B. 2012 In : Bioconjugate Chemistry. 23, 3, p. 479-84 6 p.

    Research output: Contribution to journalArticle

  46. Published

    Brainstem respiratory oscillators develop independently of neuronal migration defects in the Wnt/PCP mouse mutant looptail

    Thoby-Brisson, M., Bouvier, J., Glasco, D. M., Stewart, M. E., Dean, C., Murdoch, J. N., Champagnat, J., Fortin, G. & Chandrasekhar, A. 2012 In : PLoS One. 7, 2, p. e31140

    Research output: Contribution to journalArticle

  47. Published

    Challenges for gene therapy of CNS disorders and implications for Parkinson's disease therapies

    Broadstock, M. & Yáñez (or Yáñez-Muñoz) , R. J. 2012 In : Human Gene Therapy. 23, 4, p. 340-3 4 p.

    Research output: Contribution to journalComment/debate

  48. Published

    Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases

    Yáñez (or Yáñez-Muñoz) , R. J. , Dickson, G. , Popplewell, L. & 28 others Daboussi, F., Zaslavskiy, M., Poirot, L., Loperfido, M., Gouble, A., Guyot, V., Leduc, S., Galetto, R., Grizot, S., Oficjalska, D., Perez, C., Delacôte, F., Dupuy, A., Chion-Sotinel, I., Le Clerre, D., Lebuhotel, C., Danos, O., Lemaire, F., Oussedik, K., Cédrone, F., Epinat, J-C., Smith, J., Koo, T., Vandendriessche, T., Chuah, M. K., Duclert, A., Duchateau, P. & Pâques, F. 2012 In : Nucleic Acids Research.

    Research output: Contribution to journalArticle

  49. Published
  50. Published

    Effect of gold nanoparticle conjugation on the activity and stability of functional proteins

    Bailes, J., Gazi, S., Ivanova, R. & Soloviev, M. 2012 In : Methods in Molecular Biology. 906, p. 89-99 11 p.

    Research output: Contribution to journalArticle

  51. Published

    Evaluation of Bacillus subtilis strains as probiotics and their potential as a food ingredient

    Permpoonpattana, P., Hong, H. A., Khaneja, R. & Cutting, S. M. 2012 In : Beneficial microbes. 3, 2, p. 127-35 9 p.

    Research output: Contribution to journalArticle

  52. Published

    Genetic Therapeutic Approaches for Duchenne Muscular Dystrophy

    Foster, H., Popplewell, L. J. & Dickson, G. 2012 In : Human Gene Therapy.

    Research output: Contribution to journalScientific review

  53. Published

    Gold nanoparticle antibody conjugates for use in competitive lateral flow assays

    Bailes, J., Mayoss, S., Teale, P. & Soloviev, M. 2012 In : Methods in Molecular Biology. 906, p. 45-55 11 p.

    Research output: Contribution to journalArticle

  54. Published

    Killed Bacillus subtilis spores as a mucosal adjuvant for an H5N1 vaccine

    Song, M., Hong, H. A., Huang, J-M., Colenutt, C., Khang, D. D., Nguyen, T. V. A., Park, S-M., Shim, B-S., Song, H. H., Cheon, I. S., Jang, J. E., Choi, J., Choi, Y. K., Stadler, K. & Cutting, S. M. 2012 In : Vaccine. 30, 22, p. 3266-77 12 p.

    Research output: Contribution to journalArticle

  55. Published

    Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones

    Hutson, T. H., Foster, E., Dawes, J. M., Hindges, R., Yáñez (or Yáñez-Muñoz) , R. J. & Moon, L. D. F. 2012 In : Journal of Gene Medicine. 14, 5, p. 299-315 17 p.

    Research output: Contribution to journalArticle

  56. Published

    Novel cationic carotenoid lipids as delivery vectors of antisense oligonucleotides for exon skipping in duchenne muscular dystrophy

    Popplewell, L. J., Abu-Dayya, A., Khana, T., Flinterman, M., Khalique, N. A., Raju, L., Opstad, C. L., Sliwka, H-R., Partali, V., Dickson, G. & Pungente, M. D. 2012 In : Molecules. 17, 2, p. 1138-48 11 p.

    Research output: Contribution to journalArticle

  57. Published

    Optimizing antisense oligonucleotides using phosphorodiamidate morpholino oligomers

    Popplewell, L. J., Malerba, A. & Dickson, G. 2012 In : Methods in Molecular Biology. 867, p. 143-67 25 p.

    Research output: Contribution to journalArticle

  58. Published

    Poly(A) binding protein nuclear 1 levels affect alternative polyadenylation

    de Klerk, E., Venema, A., Anvar, S. Y., Goeman, J. J., Hu, O., Trollet, C., Dickson, G., den Dunnen, J. T., van der Maarel, S. M., Raz, V. & 't Hoen, P. A. C. 2012 In : Nucleic Acids Research.

    Research output: Contribution to journalArticle

  59. Published

    The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium

    Chang, P., Orabi, B., Deranieh, R. M., Dham, M., Hoeller, O., Shimshoni, J. A., Yagen, B., Bialer, M., Greenberg, M. L., Walker, M. C. & Williams, R. S. B. 2012 In : Disease Models and Mechanisms. 5, p. 115-124

    Research output: Contribution to journalArticle

  60. Published
  61. Published

    The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium

    Stowe, T. R., Wilkinson, C. J., Iqbal, A. & Stearns, T. 2012 In : Molecular biology of the cell. 23, 17, p. 3322-35 14 p.

    Research output: Contribution to journalArticle

  62. Published

    The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled

    Glasco, D. M., Sittaramane, V., Bryant, W., Fritzsch, B., Sawant, A., Paudyal, A., Stewart, M., Andre, P., Cadete Vilhais-Neto, G., Yang, Y., Song, M-R., Murdoch, J. N. & Chandrasekhar, A. 2012 In : Developmental Biology. 369, 2, p. 211-22 12 p.

    Research output: Contribution to journalArticle

  63. Published

    The Use of EST Expression Matrixes for the Quality Control of Gene Expression Data

    Milnthorpe, A. T. & Soloviev, M. 2012 In : PLoS One. 7, 3, p. e32966

    Research output: Contribution to journalArticle

  64. Published

    Zizimin and Dock guanine nucleotide exchange factors in cell function and disease

    Pakes, N. K., Veltman, D. M. & Williams, R. 2012 In : Small GTPases. 4, 1

    Research output: Contribution to journalArticle

  65. 2011
  66. Published

    Surface layers of Clostridium difficile endospores

    Permpoonpattana, P., Tolls, E. H., Nadem, R., Tan, S., Brisson, A. & Cutting, S. M. Dec 2011 In : Journal of Bacteriology. 193, 23, p. 6461-6470 10 p.

    Research output: Contribution to journalArticle

  67. Published

    Investigating the Effect of Emetic Compounds on Chemotaxis in Dictyostelium Identifies a Non-Sentient Model for Bitter and Hot Tastant Research

    Robery, S., Mukanowa, J., Percie du Sert, N., Andrews, P. L. R. & Williams, R. S. B. 8 Sep 2011 In : PLoS One. 6, 9, p. e24439

    Research output: Contribution to journalArticle

  68. Published

    Long-term functional adeno-associated virus-microdystrophin expression in the dystrophic CXMDj dog

    Koo, T., Okada, T., Athanasopoulos, T., Foster, H., Takeda, S. & Dickson, G. Sep 2011 In : Journal of Gene Medicine. 13, 9, p. 497-506 10 p.

    Research output: Contribution to journalArticle

  69. Published

    Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

    Cirak, S., Arechavala-Gomeza, V., Guglieri, M., Feng, L., Torelli, S., Anthony, K., Abbs, S., Garralda, M. E., Bourke, J., Wells, D. J., Dickson, G., Wood, M. J. A., Wilton, S. D., Straub, V., Kole, R., Shrewsbury, S. B., Sewry, C., Morgan, J. E., Bushby, K. & Muntoni, F. 13 Aug 2011 In : The Lancet. 378, 9791, p. 595-605 11 p.

    Research output: Contribution to journalArticle

  70. Published

    Bio-electrospraying and aerodynamically assisted bio-jetting the model eukaryotic Dictyostelium discoideum: assessing stress and developmental competency post treatment

    Pakes, N. K., Jayasinghe, S. N. & Williams, R. S. B. 7 Aug 2011 In : Journal of the Royal Society. Interface. 8, 61, p. 1185-1191 7 p.

    Research output: Contribution to journalArticle

  71. Published

    Getting to the Heart of Things in the Field of Cardiovascular Gene Therapy

    Dickson, G. Aug 2011 In : Human Gene Therapy. 22, 8, p. 911-912 2 p.

    Research output: Contribution to journalEditorial

  72. Published
  73. Published

    Identifying an uptake mechanism for the antiepileptic and bipolar disorder treatment valproic acid using the simple biomedical model Dictyostelium

    Terbach, N., Shah, R., Kelemen, R., Klein, P. S., Gordienko, D., Brown, N. A., Wilkinson, C. J. & Williams, R. S. B. 1 Jul 2011 In : Journal of Cell Science. 124, Pt 13, p. 2267-2276 10 p.

    Research output: Contribution to journalArticle

  74. Published

    Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B

    Permpoonpattana, P., Hong, H. A., Phetcharaburanin, J., Huang, J-M., Cook, J., Fairweather, N. F. & Cutting, S. M. Jun 2011 In : Infection and Immunity. 79, 6, p. 2295-2302 8 p.

    Research output: Contribution to journalArticle

  75. Published

    Identification and the developmental formation of carotenoid pigments in the yellow/orange Bacillus spore-formers

    Perez-Fons, L., Steiger, S., Khaneja, R., Bramley, P. M., Cutting, S. M., Sandmann, G. & Fraser, P. D. Mar 2011 In : Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids . 1811, 3, p. 177-185 9 p.

    Research output: Contribution to journalArticle

  76. Published

    Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice

    Malerba, A., Sharp, P. S., Graham, I. R., Arechavala-Gomeza, V., Foster, K., Muntoni, F., Wells, D. J. & Dickson, G. Feb 2011 In : Molecular Therapy. 19, 2, p. 345-354

    Research output: Contribution to journalArticle

  77. Published

    Molecular pharmacology in a simple model system: Implicating MAP kinase and phosphoinositide signalling in bipolar disorder

    Ludtmann, M. H. R., Boeckeler, K. & Williams, R. S. B. Feb 2011 In : Seminars in Cell and Developmental Biology. 22, 1, p. 105-113 9 p.

    Research output: Contribution to journalScientific review

  78. Published
  79. Published

    Adeno-associated virus serotypes 7 and 8 outperform serotype 9 in expressing atheroprotective human apoE3 from mouse skeletal muscle

    Evans, V. C., Graham, I. R., Athanasopoulos, T., Galley, D. J., Jackson, C. L., Simons, J. P., Dickson, G. & Owen, J. S. 2011 In : Metabolism: clinical and experimental. 60, 4, p. 491-8

    Research output: Contribution to journalArticle

  80. Published
  81. Published

    Bacillus probiotics

    Cutting, S. M. 2011 In : Food Microbiology. 28, 2, p. 214-20 7 p.

    Research output: Contribution to journalArticle

  82. Published

    Bioinformatic and Functional Optimization of Antisense Phosphorodiamidate Morpholino Oligomers (PMOs) for Therapeutic Modulation of RNA Splicing in Muscle

    Popplewell, L. J., Graham, I. R., Malerba, A. & Dickson, G. 2011 In : Methods in Molecular Biology. 709, p. 153-78 26 p.

    Research output: Contribution to journalArticle

  83. Published

    Carbohydrate-active enzymes from pigmented Bacilli: a genomic approach to assess carbohydrate utilization and degradation

    Manzo, N., D'Apuzzo, E., Coutinho, P. M., Cutting, S. M., Henrissat, B. & Ricca, E. 2011 In : BMC Microbiology. 11, p. 198

    Research output: Contribution to journalArticle

  84. Published

    Chromosome rearrangement associated inactivation of tumour suppressor genes in prostate cancer

    Mao, X., Boyd, L. K., Yáñez-Muñoz, R. J., Chaplin, T., Xue, L., Lin, D., Shan, L., Berney, D. M., Young, B. D. & Lu, Y. J. 2011 In : American Journal of Cancer Research. 1, p. 604-617

    Research output: Contribution to journalArticle

  85. Published

    Codon optimization of the microdystrophin gene for duchene muscular dystrophy gene therapy

    Athanasopoulos, T., Foster, H., Foster, K. & Dickson, G. 2011 In : Methods in Molecular Biology. 709, p. 21-37 17 p.

    Research output: Contribution to journalArticle

  86. Published

    Current Status of Pharmaceutical and Genetic Therapeutic Approaches to Treat DMD

    Pichavant, C., Aartsma-Rus, A., Clemens, P. R., Davies, K. E., Dickson, G., Takeda, S., Wilton, S. D., Wolff, J. A., Wooddell, C. I., Xiao, X. & Tremblay, J. P. 2011 In : Molecular Therapy. 19, 5, p. 830-40 11 p.

    Research output: Contribution to journalScientific review

  87. Published
  88. Published

    Deregulation of the ubiquitin-proteasome system is the predominant molecular pathology in OPMD animal models and patients

    Anvar, S. Y., 't Hoen, P. A., Venema, A., van der Sluijs, B., van Engelen, B., Snoeck, M., Vissing, J., Trollet, C., Dickson, G., Chartier, A., Simonelig, M., van Ommen, G-J. B., van der Maarel, S. M. & Raz, V. 2011 In : Skeletal Muscle. 1, 1, p. 15

    Research output: Contribution to journalArticle

  89. Published

    Errors in CGAP xProfiler and cDNA DGED: the importance of library parsing and gene selection algorithms

    Milnthorpe, A. T. & Soloviev, M. 2011 In : BMC Bioinformatics. 12, p. 97

    Research output: Contribution to journalArticle

  90. Published

    Lentiviral vector integration profiles differ in rodent postmitotic tissues

    Bartholomae, C. C., Arens, A., Balaggan, K. S., Yáñez-Muñoz, R. J., Montini, E., Howe, S. J., Paruzynski, A., Korn, B., Appelt, U., MacNeil, A., Cesana, D., Abel, U., Glimm, H., Naldini, L., Ali, R. R., Thrasher, A. J., von Kalle, C. & Schmidt, M. 2011 In : Molecular Therapy. 19, 4, p. 703-710

    Research output: Contribution to journalArticle

  91. Published

    Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons

    Zhao, R-R., Muir, E. M., Alves, J. N., Rickman, H., Allan, A. Y., Kwok, J. C., Roet, K. C. D., Verhaagen, J., Schneider, B. L., Bensadoun, J-C., Ahmed, S. G., Yáñez (or Yáñez-Muñoz) , R. J., Keynes, R. J., Fawcett, J. W. & Rogers, J. H. 2011 In : Journal of Neuroscience Methods. 201, 1, p. 228-38 11 p.

    Research output: Contribution to journalArticle

  92. Published

    Lobe-specific functions of Ca2+·calmodulin in alphaCa2+·calmodulin-dependent protein kinase II activation

    Jama, A. M., Gabriel, J., Al-Nagar, A. J., Martin, S., Baig, S. Z., Soleymani, H., Chowdhury, Z., Beesley, P. & Török, K. 2011 In : Journal of Biological Chemistry. 286, 14, p. 12308-16 9 p.

    Research output: Contribution to journalArticle

  93. Published

    RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense

    Riyahi, T. Y., Frese, F., Steinert, M., Omosigho, N. N., Glöckner, G., Eichinger, L., Orabi, B., Williams, R. S. B. & Noegel, A. A. 2011 In : PLoS One. 6, 11, p. e27311

    Research output: Contribution to journalArticle

  94. Published

    Transcription Factor Rational Design Improves Directed Differentiation of Human Mesenchymal Stem Cells Into Skeletal Myocytes

    Gonçalves, M. A., Janssen, J. M., Nguyen, Q. G., Athanasopoulos, T., Hauschka, S. D., Dickson, G. & de Vries, A. A. 2011 In : Molecular Therapy. 19, 7, p. 1331-41

    Research output: Contribution to journalArticle

  95. 2010
  96. Published

    NanoLock polypeptide for the permanent immobilization of recombinant proteins on SNAP25 functionalized supports

    Ferrari, E., Darios, F., Soloviev, M. & Davletov, B. 1 Nov 2010 In : European Cells and Materials. 20, SUPPL.3, p. 80 1 p.

    Research output: Contribution to journalArticle

  97. Published

    Canine microdystrophin results in remarkable expression and improvement in muscle pathology in a canine model of Duchenne Muscular Dystrophy following AAV gene transfer

    Koo, T., Shin, J. H., Athanasopoulos, T., Takashi, O., Foster, H., Shin'ichi, T. & Dickson, G. Oct 2010 In : Human Gene Therapy. 21, 10, p. 1469-1470 2 p.

    Research output: Contribution to journalArticle

  98. Published

    Evaluation of the truncated products of exon and multiple exon skipping in DMD therapy

    Foster, K., Jarmin, S., Beley, C., Foster, H., Garcia, L. & Dickson, G. Oct 2010 In : Neuromuscular Disorders. 20, 9-10, p. 642 1 p.

    Research output: Contribution to journalArticle

  99. Published

    Serum Proteomics in the Diagnosis and Treatment of Haematological Malignancies

    Smieszek, S., Bailes, J. & Soloviev, M. Oct 2010 In : Current Proteomics . 7, 3, p. 195-208 14 p.

    Research output: Contribution to journalScientific review

  100. Published

    Inhibition of long-term potentiation by valproic acid through modulation of cyclic AMP

    Chang, P., Chandler, K. E., Williams, R. S. B. & Walker, M. C. Aug 2010 In : Epilepsia. 51, 8, p. 1533-1542 10 p.

    Research output: Contribution to journalArticle

  101. Published

    Epidermal wound repair is regulated by the planar cell polarity signaling pathway

    Caddy, J., Wilanowski, T., Darido, C., Dworkin, S., Ting, S. B., Zhao, Q., Rank, G., Auden, A., Srivastava, S., Papenfuss, T. A., Murdoch, J. N., Humbert, P. O., Boulos, N., Weber, T., Zuo, J., Cunningham, J. M. & Jane, S. M. 20 Jul 2010 In : Developmental Cell. 19, 1, p. 138-147 10 p.

    Research output: Contribution to journalArticle

  102. Published

    Genetic Control of Lithium Sensitivity and Regulation of Inositol Biosynthetic Genes

    King, J., Keim, M., Teo, R., Weening, K. E., Kapur, M., McQuillan, K., Ryves, J., Rogers, B., Dalton, E., Williams, R. S. B. & Harwood, A. J. 17 Jun 2010 In : PLoS One. 5, 6, 10 p.

    Research output: Contribution to journalArticle

  103. Published

    Molecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres

    Trollet, C., Anvar, S. Y., Venema, A., Hargreaves, I. P., Foster, K., Vignaud, A., Ferry, A., Negroni, E., Hourde, C., Baraibar, M. A., 't Hoen, P. A. C., Davies, J. E., Rubinsztein, D. C., Heales, S. J., Mouly, V., van der Maarel, S. M., Butler-Browne, G., Raz, V. & Dickson, G. 1 Jun 2010 In : Human Molecular Genetics. 19, 11, p. 2191-2207 17 p.

    Research output: Contribution to journalArticle

  104. Published

    Carotenoids found in Bacillus

    Khaneja, R., Perez-Fons, L., Fakhry, S., Baccigalupi, L., Steiger, S., To, E., Sandmann, G., Dong, T. C., Ricca, E., Fraser, P. D. & Cutting, S. M. Jun 2010 In : Journal of applied microbiology. 108, 6, p. 1889-1902 14 p.

    Research output: Contribution to journalArticle

  105. Published

    A justice system that denies free will is not based on justice

    McEvoy, J. P. 18 May 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 20, p. E81-E81 1 p.

    Research output: Contribution to journalLetter

  106. Published

    Antisense Oligonucleotide-Induced Multiexon Skipping in Duchenne Muscular Dystrophy

    Popplewell, L. J. & Dickson, G. Apr 2010 In : Human Gene Therapy. 21, 4, p. 507-508 2 p.

    Research output: Contribution to journalMeeting abstract

  107. Published

    Reduced expression of the Ca2+transporter protein PMCA2 slows Ca2+dynamics in mouse cerebellar Purkinje neurones and alters the precision of motor coordination

    Empson, R. M., Turner, P. R., Nagaraja, R. Y., Beesley, P. W. & Knopfel, T. 15 Mar 2010 In : Journal of Physiology . 588, 6, p. 907-922 16 p.

    Research output: Contribution to journalArticle

  108. Published

    Affinity peptidomics: Peptide selection and affinity capture on hydrogels and microarrays

    Zhang, F., Dulneva, A., Bailes, J. & Soloviev, M. 2010 In : Methods in Molecular Biology. 615, p. 313-44 32 p.

    Research output: Contribution to journalArticle

  109. Published

    Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice

    Qu, Y., Glasco, D. M., Zhou, L., Sawant, A., Ravni, A., Fritzsch, B., Damrau, C., Murdoch, J. N., Evans, S., Pfaff, S. L., Formstone, C., Goffinet, A. M., Chandrasekhar, A. & Tissir, F. 2010 In : The Journal of Neuroscience. 30, 28, p. 9392-401 10 p.

    Research output: Contribution to journalArticle

  110. Published

    Bacterial-type oxygen detoxification and iron-sulfur cluster assembly in amoebal relict mitochondria

    Maralikova, B., Ali, V., Nakada-Tsukui, K., Nozaki, T., van der Giezen, M., Henze, K. & Tovar, J. 2010 In : Cellular Microbiology. 12, 3, p. 331-42 12 p.

    Research output: Contribution to journalArticle

  111. Published

    Basal enrichment within neuroepithelia suggests novel function(s) for Celsr1 protein

    Formstone, C. J., Moxon, C., Murdoch, J., Little, P. & Mason, I. 2010 In : Molecular and Cellular Neuroscience. 44, 3, p. 210-22 13 p.

    Research output: Contribution to journalArticle

  112. Published

    Binary polypeptide system for permanent and oriented protein immobilization

    Ferrari, E., Darios, F., Zhang, F., Niranjan, D., Bailes, J., Soloviev, M. & Davletov, B. 2010 In : Journal of Nanobiotechnology. 8, p. 9

    Research output: Contribution to journalArticle

  113. Published

    Challenges with advanced therapy medicinal products and how to meet them

    Dickson, J. G. & 66 others Schneider, C. K., Salmikangas, P., Jilma, B., Flamion, B., Todorova, L. R., Paphitou, A., Haunerova, I., Maimets, T., Trouvin, J-H., Flory, E., Tsiftsoglou, A., Sarkadi, B., Gudmundsson, K., O'Donovan, M., Migliaccio, G., Ancāns, J., Maciulaitis, R., Robert, J-L., Samuel, A., Ovelgönne, J. H., Hystad, M., Fal, A. M., Lima, B. S., Moraru, A. S., Turcáni, P., Zorec, R., Ruiz, S., Akerblom, L., Narayanan, G., Kent, A., Bignami, F., Niederwieser, D., Figuerola-Santos, M-A., Reischl, I. G., Beuneu, C., Georgiev, R., Vassiliou, M., Pychova, A., Clausen, M., Methuen, T., Lucas, S., Schüssler-Lenz, M., Kokkas, V., Buzás, Z., MacAleenan, N., Galli, M. C., Linē, A., Gulbinovic, J., Berchem, G., Fraczek, M., Menezes-Ferreira, M., Vilceanu, N., Hrubisko, M., Marinko, P., Timón, M., Cheng, W., Crosbie, G. A., Meade, N., di Paola, M. L., VandenDriessche, T., Ljungman, P., D'Apote, L., Oliver-Diaz, O., Büttel, I., Celis, P. & Committee for Advanced Therapies (CAT) 2010 In : Nature Reviews. Drug Discovery. 9, 3, p. 195-201 7 p.

    Research output: Contribution to journalArticle

  114. Published

    Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials

    Popplewell, L. J., Adkin, C., Arechavala-Gomeza, V., Aartsma-Rus, A., de Winter, C. L., Wilton, S. D., Morgan, J. E., Muntoni, F., Graham, I. R. & Dickson, G. 2010 In : Neuromuscular disorders. 20, 2, p. 102-10 9 p.

    Research output: Contribution to journalArticle

  115. Published

    Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat

    Yip, P. K., Wong, L. F., Sears, T. A., Yáñez-Muñoz, R. J. & McMahon, S. B. 2010 In : PLoS Biology. 8, 6, e1000399

    Research output: Contribution to journalArticle

  116. Published

    Labelling of live cells using fluorescent aptamers: binding reversal with DNA nucleases

    Terazono, H., Anzai, Y., Soloviev, M. & Yasuda, K. 2010 In : Journal of Nanobiotechnology. 8, p. 8

    Research output: Contribution to journalArticle

  117. Published

    Mucosal delivery of antigens using adsorption to bacterial spores

    Huang, J-M., Hong, H. A., Van Tong, H., Hoang, T. H., Brisson, A. & Cutting, S. M. 2010 In : Vaccine. 28, 4, p. 1021-30 10 p.

    Research output: Contribution to journalArticle

  118. Published

    Oral delivery of a DNA vaccine against tuberculosis using operator-repressor titration in a Salmonella enterica vector

    Huang, J-M., Sali, M., Leckenby, M. W., Radford, D. S., Huynh, H. A., Delogu, G., Cranenburgh, R. M. & Cutting, S. M. 2010 In : Vaccine. 28, 47, p. 7523-8 6 p.

    Research output: Contribution to journalArticle

  119. Published

    Peptidomics: divide et impera

    Soloviev, M. 2010 In : Methods in Molecular Biology. 615, p. 3-9 7 p.

    Research output: Contribution to journalArticle

  120. Published

    Production of non viral DNA vectors

    Schleef, M., Blaesen, M., Schmeer, M., Baier, R., Marie, C., Dickson, G. & Scherman, D. 2010 In : Current Gene Therapy. 10, 6, p. 487-507 21 p.

    Research output: Contribution to journalArticle

  121. Published

    Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary cilia

    Sugiyama, Y., Stump, R. J. W., Nguyen, A., Wen, L., Chen, Y., Wang, Y., Murdoch, J. N., Lovicu, F. J. & McAvoy, J. W. 2010 In : Developmental Biology. 338, 2, p. 193-201 9 p.

    Research output: Contribution to journalArticle

  122. Published

    SNARE tagging allows stepwise assembly of a multimodular medicinal toxin

    Darios, F., Niranjan, D., Ferrari, E., Zhang, F., Soloviev, M., Rummel, A., Bigalke, H., Suckling, J., Ushkaryov, Y., Naumenko, N., Shakirzyanova, A., Giniatullin, R., Maywood, E., Hastings, M., Binz, T. & Davletov, B. 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 42, p. 18197-201 5 p.

    Research output: Contribution to journalArticle

  123. Published

    The Bone Morphogenetic Protein and Growth Differentiation Cytokine Family, and their Protein Antagonists

    Rider, C. C. & Mulloy, B. 2010 In : Biochemical Journal. 429, p. 1-12 12 p.

    Research output: Contribution to journalScientific review

  124. Published

    The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain

    Goncalves, M. B., Williams, E. J., Yip, P., Yáñez-Muñoz, R. J., Williams, G. & Doherty, P. 2010 In : British Journal of Pharmacology. 159, 5, p. 1118-25 8 p.

    Research output: Contribution to journalArticle

  125. Published

    The identification of chromosomal translocation, t(4;6)(q22;q15), in prostate cancer

    Yáñez-Muñoz, R. J. & 23 others Shan, L., Ambroisine, L., Clark, J., Fisher, G., Kudahetti, S. C., Yang, J., Kia, S., Mao, X., Fletcher, A., Flohr, P., Edwards, S., Attard, G., De-Bono, J., Young, B. D., Foster, C. S., Reuter, V., Moller, H., Oliver, T. D., Berney, D. M., Scardino, P., Cuzick, J., Cooper, C. S. & Lu, Y. J. 2010 In : Prostate Cancer and Prostatic Diseases. 13, 2, p. 117-25 9 p.

    Research output: Contribution to journalArticle

  126. Published

    The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

    Paudyal, A., Damrau, C., Patterson, V. L., Ermakov, A., Formstone, C., Lalanne, Z., Wells, S., Lu, X., Norris, D. P., Dean, C. H., Henderson, D. J. & Murdoch, J. N. 2010 In : BMC Developmental Biology. 10, p. 87

    Research output: Contribution to journalArticle

  127. Published

    The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

    Yates, L. L., Schnatwinkel, C., Murdoch, J. N., Bogani, D., Formstone, C. J., Townsend, S., Greenfield, A., Niswander, L. A. & Dean, C. H. 2010 In : Human Molecular Genetics. 19, 11, p. 2251-2267 17 p.

    Research output: Contribution to journalArticle

  128. Published

    The relationship between Sonic hedgehog signalling, cilia and neural tube defects.

    Murdoch, J. N. & Copp, A. J. 2010 In : Birth Defects Research Part A: Clinical and Molecular Teratology. 88, p. 633-652

    Research output: Contribution to journalArticle

  129. Published

    Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization

    Ghahramani Seno, M. M., Trollet, C., Athanasopoulos, T., Graham, I. R., Hu, P. & Dickson, G. 2010 In : BMC Genomics. 11, p. 345

    Research output: Contribution to journalArticle

  130. Published

    Using single cell cultivation system for on-chip monitoring of the interdivision timer in Chlamydomonas reinhardtii cell cycle

    Matsumura, K., Yagi, T., Hattori, A., Soloviev, M. & Yasuda, K. 2010 In : Journal of Nanobiotechnology. 8, p. 23

    Research output: Contribution to journalArticle

  131. 2009
  132. Published

    Development of thermo-stable Ad-based vaccines expressing ubiquitin fusions of full or fragmented HIV/SIV genetic components

    Athanasopoulos, T., Papagatsias, T., Meiser, A., Harris, J., Bachy, V., Benlahrech, A., Herath, S., Roesen, N., Oh, S., Li, F., Self, S., Kwon, S-Y., Fischer, K., Seymour, L., Daniels, R., Almond, N., Klavinskis, L., Logan, K., Patterson, S. & Dickson, G. Nov 2009 In : Human Gene Therapy. 20, 11, p. 1392-1393 2 p.

    Research output: Contribution to journalArticle

  133. Published

    Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

    Popplewell, L. , Dickson, G. & 23 others Kinali, M., Arechavala-Gomeza, V., Feng, L., Cirak, S., Hunt, D., Adkin, C., Guglieri, M., Ashton, E., Abbs, S., Nihoyannopoulos, P., Garralda, M. E., Rutherford, M., McCulley, C., Graham, I. R., Wood, M. J. A., Wells, D. J., Wilton, S. D., Kole, R., Straub, V., Bushby, K., Sewry, C., Morgan, J. E. & Muntoni, F. Oct 2009 In : Lancet Neurology. 8, 10, p. 918-928 11 p.

    Research output: Contribution to journalArticle

  134. Published

    PtdIns(3,4,5)P-3 and inositol depletion as a cellular target of mood stabilizers

    Teo, R., King, J., Dalton, E., Ryves, J., Williams, R. S. B. & Harwood, A. J. Oct 2009 In : Biochemical Society Transactions. 37, p. 1110-1114 5 p.

    Research output: Contribution to journalArticle

  135. Published

    Structure-function studies for the panacea, valproic acid

    Terbach, N. & Williams, R. S. B. Oct 2009 In : Biochemical Society Transactions. 37, p. 1126-1132 7 p.

    Research output: Contribution to journalArticle

  136. Published

    MOLECULAR INTERACTIONS OF THE PLASMA MEMBRANE CALCIUM ATPase 2 AT PRE- AND POST-SYNAPTIC SITES IN RAT CEREBELLUM

    Garside, M. L., Turner, P. R., Austen, B., Strehler, E. E., Beesley, P. W. & Empson, R. M. 18 Aug 2009 In : Neuroscience. 162, 2, p. 383-395 13 p.

    Research output: Contribution to journalArticle

  137. Published

    Gene therapy for muscular dystrophy: current progress and future prospects

    Trollet, C., Athanasopoulos, T., Popplewell, L., Malerba, A. & Dickson, G. Jul 2009 In : Expert Opinion on Biological Therapy. 9, 7, p. 849-866 18 p.

    Research output: Contribution to journalScientific review

  138. Published

    Pharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytes

    Puddifoot, C. A., Chen, P. E., Schoepfer, R. & Wyllie, D. J. A. Feb 2009 In : British Journal of Pharmacology. 156, 3, p. 509-518 10 p.

    Research output: Contribution to journalArticle

  139. Published

    Oral vaccine delivery by recombinant spore probiotics

    Cutting, S. M., Hong, H. A., Baccigalupi, L. & Ricca, E. 1 Jan 2009 In : International Reviews of Immunology. 28, 6, p. 487-505 19 p.

    Research output: Contribution to journalArticle

  140. Published

    Adeno-associated virus-8-mediated intravenous transfer of myostatin propeptide leads to systemic functional improvements of slow but not fast muscle

    Foster, K., Graham, I. R., Otto, A., Foster, H., Trollet, C., Yaworsky, P. J., Walsh, F. S., Bickham, D., Curtin, N. A., Kawar, S. L., Patel, K. & Dickson, G. 2009 In : Rejuvenation Research. 12, 2, p. 85-94 10 p.

    Research output: Contribution to journalArticle

  141. Published

    Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1

    Benlahrech, A., Harris, J., Meiser, A., Papagatsias, T., Hornig, J., Hayes, P., Lieber, A., Athanasopoulos, T., Bachy, V., Csomor, E., Daniels, R., Fisher, K., Gotch, F., Seymour, L., Logan, K., Barbagallo, R., Klavinskis, L., Dickson, G. & Patterson, S. 2009 In : Proceedings of the National Academy of Sciences of the United States of America. 106, 47, p. 19940-5 6 p.

    Research output: Contribution to journalArticle

  142. Published

    Bacillus subtilis isolated from the human gastrointestinal tract

    Huynh, H., Khaneja, R., Tam, N. M. K., Cazzato, A., Tan, S., Urdaci, M., Brisson, A., Gasbarrini, A., Barnes, I. & Cutting, S. M. 2009 In : Research in Microbiology. 160, 2, p. 134-143 10 p.

    Research output: Contribution to journalArticle

  143. Published

    Behavioral deficits and subregion-specific suppression of LTP in mice expressing a population of mutant NMDA receptors throughout the hippocampus

    Chen, P. E., Errington, M. L., Kneussel, M., Chen, G., Annala, A. J., Rudhard, Y. H., Rast, G. F., Specht, C. G., Tigaret, C. M., Nassar, M. A., Morris, R. G. M., Bliss, T. V. P. & Schoepfer, R. 2009 In : Learning and Memory. 16, 10, p. 635-644 10 p.

    Research output: Contribution to journalArticle

  144. Published

    Bipolar disorder: molecular and cellular biology

    Williams, R. 2009 In : Biochemist. October, p. 54-55

    Research output: Contribution to journalArticle

  145. Published

    Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos

    Wilkinson, C. J., Carl, M. & Harris, W. A. 2009 In : BMC Cell Biology. 10, p. 17 1 p.

    Research output: Contribution to journalArticle

  146. Published

    Comprehensive genomic access to vector integration in clinical gene therapy

    Yáñez-Muñoz, R. J. & 30 others Gabriel, R., Eckenberg, R., Paruzynski, A., Bartholomae, C. C., Nowrouzi, A., Arens, A., Howe, S. J., Recchia, A., Cattoglio, C., Wang, W., Faber, K., Schwarzwaelder, K., Kirsten, R., Deichmann, A., Ball, C. R., Balaggan, K. S., Ali, R. R., Gaspar, H. B., Biasco, L., Aiuti, A., Cesana, D., Montini, E., Naldini, L., Cohen-Haguenauer, O., Mavilio, F., Thrasher, A. J., Glimm, H., von Kalle, C., Saurin, W. & Schmidt, M. 2009 In : Nature Medicine. 15, 12, p. 1431-1436 6 p.

    Research output: Contribution to journalArticle

  147. Published

    Defining the natural habitat of Bacillus spore-formers

    Huynh, H., To, E., Fakhry, S., Baccigalupi, L., Ricca, E. & Cutting, S. M. 2009 In : Research in Microbiology. 160, 6, p. 375-9 5 p.

    Research output: Contribution to journalArticle

  148. Published

    Design of phosphorodiamidate morpholino oligomers (PMOs) for the induction of exon skipping of the human DMD gene

    Popplewell, L. J., Trollet, C., Dickson, G. & Graham, I. R. 2009 In : Molecular Therapy. 17, 3, p. 554-61 8 p.

    Research output: Contribution to journalArticle

  149. Published

    Dosing regimen has a significant impact on the efficiency of morpholino oligomer-induced exon skipping in mdx mice

    Malerba, A., Thorogood, F. C., Dickson, G. & Graham, I. R. 2009 In : Human Gene Therapy. 20, 9, p. 955-65 11 p.

    Research output: Contribution to journalArticle

  150. Published

    Efficient liver-directed gene transfer by in situ generation of retroviral vector from adenoviral templates

    Harris, J. D., Roberts, M. L., Perumal, D., Graham, I. R., Patterson, S. & Dickson, G. 2009 In : In Vivo. 23, 6, p. 885-93 9 p.

    Research output: Contribution to journalArticle

  151. Published

    Employing multiple models, methods and mechanisms in bipolar disorder research

    Williams, R. S. B. 2009 In : Biochemical Society Transactions. 37, Pt 5, p. 1077-9 3 p.

    Research output: Contribution to journalArticle

  152. Published

    Evidence for a homodimeric structure of human monocarboxylate transporter 8

    Visser, W. E., Philp, N. J., van Dijk, T. B., Klootwijk, W., Friesema, E. C. H., Jansen, J., Beesley, P., Ianculescu, A. G. & Visser, T. J. 2009 In : Endocrinology. 150, 11, p. 5163-70 8 p.

    Research output: Contribution to journalArticle

  153. Published

    Inhibition of rat recombinant GluN1/GluN2A and GluN1/GluN2B NMDA receptors by ethanol at concentrations based on the US/UK drink-drive limit

    Otton, H. J., Janssen, A., O'Leary, T., Chen, P. E. & Wyllie, D. J. 2009 In : European Journal of Pharmacology. 614, 1-3, p. 14-21 8 p.

    Research output: Contribution to journalArticle

  154. Published

    Integration-deficient Lentiviral Vectors: A Slow Coming of Age

    Wanisch, K. & Yáñez-Muñoz, R. J. 2009 In : Molecular Therapy. 17, 8, p. 1316-1332

    Research output: Contribution to journalScientific review

  155. Published

    Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice

    Foster, K., Matsakas, A., Otto, A., Macharia, R., Elashry, M. I., Feist, S., Graham, I., Foster, H., Yaworsky, P., Walsh, F., Dickson, G. & Patel, K. 2009 In : Neuromuscular disorders. 19, 7, p. 489-99 11 p.

    Research output: Contribution to journalArticle

  156. Published

    Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway

    Patterson, V. L., Damrau, C., Paudyal, A., Reeve, B., Grimes, D. T., Stewart, M. E., Williams, D. J., Siggers, P., Greenfield, A. & Murdoch, J. N. 2009 In : Human Molecular Genetics. 18, 10, p. 1719-1739 21 p.

    Research output: Contribution to journalArticle

  157. Published

    N-terminal acetylation of the neuronal protein SNAP-25 is revealed by the SMI81 monoclonal antibody

    Connell, E., Darios, F., Peak-Chew, S., Soloviev, M. & Davletov, B. 2009 In : Biochemistry. 48, 40, p. 9582-9 8 p.

    Research output: Contribution to journalArticle

  158. Published

    Preliminary evaluation of a self-complementary AAV2/8 vector for hepatic gene transfer of human apoE3 to inhibit atherosclerotic lesion development in apoE-deficient mice

    Osman, E., Evans, V., Graham, I. R., Athanasopoulos, T., McIntosh, J., Nathwani, A. C., Simons, J. P., Dickson, G. & Owen, J. S. 2009 In : Atherosclerosis. 204, 1, p. 121-6 6 p.

    Research output: Contribution to journalArticle

  159. Published

    Quantifying in vivo phosphoinositide turnover in chemotactically-competent Dictyostelium cells

    Pawolleck, N. & Williams, R. S. 2009 Chemotaxis: Methods and Protocols. Jin, T. & Hereld, D. (eds.). Humana Press, p. 283-90 8 p. (Methods in Molecular Biology; vol. 571)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  160. Published

    Quantum dots improve peptide detection in MALDI MS in a size dependent manner

    Bailes, J., Vidal, L., Ivanov, D. A. & Soloviev, M. 2009 In : Journal of Nanobiotechnology. 7, p. 10

    Research output: Contribution to journalArticle

  161. Published

    Searching for protein-protein interactions within the Bacillus subtilis spore coat

    Krajcíková, D., Lukácová, M., Müllerová, D., Cutting, S. M. & Barák, I. 2009 In : Journal of Bacteriology. 191, 10, p. 3212-9 8 p.

    Research output: Contribution to journalArticle

  162. Published

    The effect of anti-spore antibody responses on the use of spores for vaccine delivery

    Yu, L. H. & Cutting, S. M. 2009 In : Vaccine. 27, 34, p. 4576-84 9 p.

    Research output: Contribution to journalArticle

  163. Published

    The mood stabiliser lithium suppresses PIP3 signalling in Dictyostelium and human cells

    King, J. S., Teo, R., Ryves, J., Reddy, J. V., Peters, O., Orabi, B., Hoeller, O., Williams, R. S. B. & Harwood, A. J. 2009 In : Disease Models and Mechanisms. 2, 5-6, p. 306-312 7 p.

    Research output: Contribution to journalArticle

  164. 2008
  165. Published

    Redox Reactions of the Non-Heme Iron in Photosystem II: An EPR Spectroscopic Study

    McEvoy, J. P. & Brudvig, G. W. 16 Dec 2008 In : Biochemistry. 47, 50, p. 13394-13403 10 p.

    Research output: Contribution to journalArticle

  166. Published

    Recombinant Bacillus subtilis expressing the Clostridium perfringens alpha toxoid is a candidate orally delivered vaccine against necrotic enteritis

    Hoang, T. H., Hong, H. A., Clark, G. C., Titball, R. W. & Cutting, S. M. Nov 2008 In : Infection and Immunity. 76, 11, p. 5257-5265 9 p.

    Research output: Contribution to journalArticle

  167. Published
  168. Published

    Comprehensive gene expression atlas for the Arabidopsis MAP kinase signalling pathways

    Menges, M., Doczi, R., Okresz, L., Morandini, P., Mizzi, L., Soloviev, M., Murray, J. A. H. & Bogre, L. Aug 2008 In : New Phytologist. 179, 3, p. 643-662 20 p.

    Research output: Contribution to journalArticle

  169. Published

    The safety of Bacillus subtilis and Bacillus indicus as food probiotics

    Hong, H. A., Huang, J. -M., Khaneja, R., Hiep, L. V., Urdaci, M. C. & Cutting, S. M. Aug 2008 In : Journal of applied microbiology. 105, 2, p. 510-520 11 p.

    Research output: Contribution to journalArticle

  170. Published

    Computational insights into the O-2-evolving complex of photosystem II

    Sproviero, E. M., McEvoy, J. P., Gascon, J. A., Brudvig, G. W. & Batista, V. S. Jul 2008 In : Photosynthesis Research. 97, 1, p. 91-114 24 p.

    Research output: Contribution to journalScientific review

  171. Published

    A model of the oxygen-evolving center of photosystem II predicted by structural refinement based on EXAFS Simulations

    Sproviero, E. M., Gascon, J. A., McEvoy, J. P., Brudvig, G. W. & Batista, V. S. 28 May 2008 In : Journal of the American Chemical Society. 130, 21, p. 6728-6730 3 p.

    Research output: Contribution to journalArticle

  172. Published

    QM/MM computational studies of substrate water binding to the oxygen-evolving centre of photosystem II

    Sproviero, E. M., Shinopoulos, K., Gascon, J. A., McEvoy, J. P., Brudvig, G. W. & Batista, V. S. 27 Mar 2008 In : Philosophical Transactions of the Royal Society of London B: Biological Sciences. 363, 1494, p. 1149-1156 8 p.

    Research output: Contribution to journalArticle

  173. Published

    Quantum mechanics/molecular mechanics study of the catalytic cycle of water splitting in photosystem II

    Sproviero, E. M., Gascon, J. A., McEvoy, J. P., Brudvig, G. W. & Batista, V. S. 19 Mar 2008 In : Journal of the American Chemical Society. 130, 11, p. 3428-3442 15 p.

    Research output: Contribution to journalScientific review

  174. Published

    Computational studies of the O-2-evolving complex of photosystem II and biomimetic oxomanganese complexes

    Sproviero, E. M., Gascon, J. A., McEvoy, J. P., Brudvig, G. W. & Batista, V. S. Feb 2008 In : Coordination Chemistry Reviews. 252, 3-4, p. 395-415 21 p.

    Research output: Contribution to journalScientific review

  175. Published

    Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

    Wrighton, D. C., Baker, E. J., Chen, P. E. & Wyllie, D. J. A. 1 Jan 2008 In : Journal of Physiology. 586, 1, p. 211-225 15 p.

    Research output: Contribution to journalArticle

  176. Published

    Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

    Chen, P. E., Geballe, M. T., Katz, E., Erreger, K., Livesey, M. R., O'Toole, K. K., Le, P., Lee, C. J., Snyder, J. P., Traynelis, S. F. & Wyllie, D. J. A. 1 Jan 2008 In : Journal of Physiology . 586, 1, p. 227-245 19 p.

    Research output: Contribution to journalArticle

  177. Published

    Coelomic expression of a novel bone morphogenetic protein in regenerating arms of the brittle star Amphiura filiformis

    Bannister, R., McGonnell, I. M., Graham, A., Thorndyke, M. C. & Beesley, P. W. Jan 2008 In : Development Genes and Evolution. 218, 1, p. 33-38 6 p.

    Research output: Contribution to journalArticle

  178. Published

    A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner

    Goncalves, M. B., Suetterlin, P., Yip, P., Molina-Holgado, F., Walker, D. J., Oudin, M. J., Zentar, M. P., Pollard, S., Yáñez-Muñoz, R. J., Williams, G., Walsh, F. S., Pangalos, M. N. & Doherty, P. 2008 In : Molecular and Cellular Neuroscience. 38, 4, p. 526-36 11 p.

    Research output: Contribution to journalArticle

  179. Published

    Activity of different vaccine-associated promoter elements in human dendritic cells

    Papagatsias, T., Rozis, G., Athanasopoulos, T., Gotch, F., Dickson, G. & Patterson, S. 2008 In : Immunology Letters. 115, 2, p. 117-25 9 p.

    Research output: Contribution to journalArticle

  180. Published

    Adenovirus-based targeting in myoblasts is hampered by nonhomologous vector integration

    Isman, O., Roberts, M. L., Morgan, J. E., Graham, I. R., Goldring, K., Lawrence-Watt, D. J., Lu, Q. L., Dunckley, M. G., Porter, A. C. G., Partridge, T. A. & Dickson, G. 2008 In : Human Gene Therapy. 19, 10, p. 1000-8 9 p.

    Research output: Contribution to journalArticle

  181. Published

    Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer

    Foster, H., Sharp, P. S., Athanasopoulos, T., Trollet, C., Graham, I. R., Foster, K., Wells, D. J. & Dickson, G. 2008 In : Molecular Therapy. 16, 11, p. 1825-32 8 p.

    Research output: Contribution to journalArticle

  182. Published

    Cytoplasmic delivery of antigens, by Bacillus subtilis enhances Th1 responses

    Huang, J-M., La Ragione, R. M., Cooley, W. A., Todryk, S. & Cutting, S. M. 2008 In : Vaccine. 26, 48, p. 6043-52 10 p.

    Research output: Contribution to journalArticle

  183. Published

    Entamoeba histolytica mitosomes: organelles in search of a function

    Aguilera, P., Barry, T. & Tovar, J. 2008 In : Experimental Parasitology. 118, 1, p. 10-6 7 p.

    Research output: Contribution to journalScientific review

  184. Published

    Genomic insertion of lentiviral DNA circles directed by the yeast Flp recombinase

    Moldt, B., Staunstrup, N. H., Jakobsen, M., Yáñez-Muñoz, R. J. & Mikkelsen, J. G. 2008 In : BMC Biotechnology. 8, p. 60 10 p.

    Research output: Contribution to journalArticle

  185. Published

    Human apolipoprotein E expression from mouse skeletal muscle by electrotransfer of nonviral DNA (plasmid) and pseudotyped recombinant adeno-associated virus (AAV2/7)

    Evans, V., Foster, H., Graham, I. R., Foster, K., Athanasopoulos, T., Simons, J. P., Dickson, G. & Owen, J. S. 2008 In : Human Gene Therapy. 19, 6, p. 569-78 10 p.

    Research output: Contribution to journalArticle

  186. Published

    Immunostimulatory activity of Bacillus spores

    Huang, J-M., La Ragione, R. M., Nunez, A. & Cutting, S. M. 2008 In : FEMS Immunology and Medical Microbiology . 53, 2, p. 195-203 9 p.

    Research output: Contribution to journalArticle

  187. Published

    Impaired telomerase activity in human cells expressing GFP-Ku86 fusion proteins

    Badie, C., Yáñez-Muñoz, R. J., Muller, C., Salles, B. & Porter, A. C. 2008 In : Cytogenetic and Genome Research. 122, 3-4, p. 326-35 10 p.

    Research output: Contribution to journalArticle

  188. Published

    Non-cell-autonomous roles for the planar cell polarity gene Vangl2 in development of the coronary circulation

    Phillips, H. M., Hildreth, V., Peat, J. D., Murdoch, J. N., Kobayashi, K., Chaudhry, B. & Henderson, D. J. 2008 In : Circulation Research. 102, 5, p. 615-623 9 p.

    Research output: Contribution to journalArticle

  189. Published

    Redox reactions of the non-heme iron of photosystem II: An EPR spectroscopic study

    McEvoy, J. & Brudvig, G. W. 2008 Photosynthesis: Energy from the Sun. Springer, p. 141-144

    Research output: Chapter in Book/Report/Conference proceedingChapter

  190. Published

    RNAi-mediated knockdown of dystrophin expression in adult mice does not lead to overt muscular dystrophy pathology

    Ghahramani Seno, M. M., Graham, I. R., Athanasopoulos, T., Trollet, C., Pohlschmidt, M., Crompton, M. R. & Dickson, G. 2008 In : Human Molecular Genetics. 17, 17, p. 2622-32 11 p.

    Research output: Contribution to journalArticle

  191. Published

    The impact of the absence of aliphatic glucosinolates on insect herbivory in Arabidopsis

    Beekwilder, J., van Leeuwen, W., van Dam, N. M., Bertossi, M., Grandi, V., Mizzi, L., Soloviev, M., Szabados, L., Molthoff, J. W., Schipper, B., Verbocht, H., de Vos, R. C. H., Morandini, P., Aarts, M. G. M. & Bovy, A. 2008 In : PLoS One. 3, 4, p. e2068

    Research output: Contribution to journalArticle

  192. Published

    The safety of two Bacillus probiotic strains for human use

    Sorokulova, I. B., Pinchuk, I. V., Denayrolles, M., Osipova, I. G., Huang, J. M., Cutting, S. M. & Urdaci, M. C. 2008 In : Digestive Diseases and Sciences. 53, 4, p. 954-63 10 p.

    Research output: Contribution to journalArticle

  193. 2007
  194. Published

    Comparative analysis of antisense oligonucleotide sequences for targeted skipping of Exon 51 during dystrophin Pre-mRNA splicing in human muscle

    Arechavala-Gomeza, V., Graham, I. R., Popplewell, L. J., Adams, A. M., Aartsma-Rus, A., Kinali, M., Morgan, J. E., Van Deutekom, J. C., Wilton, S. D., Dickson, G. & Muntoni, F. Sep 2007 In : Human Gene Therapy. 18, 9, p. 798-810 13 p.

    Research output: Contribution to journalArticle

  195. Published

    Attenuation of phospholipid signaling provides a novel mechanism for the action of valproic acid

    Xu, X., Mueller-Taubenberger, A., Adley, K. E., Pawolleck, N., Lee, V. W. Y., Wiedemann, C., Sihra, T. S., Maniak, M., Jin, T. & Williams, R. S. B. Jun 2007 In : EUKARYOTIC CELL. 6, 6, p. 899-906 8 p.

    Research output: Contribution to journalArticle

  196. Published

    Quantum mechanics/molecular mechanics structural models of the oxygen-evolving complex of photosystem II

    Sproviero, E. M., Gascon, J. A., McEvoy, J. P., Brudvig, G. W. & Batista, V. S. Apr 2007 In : Current opinion in structural biology. 17, 2, p. 173-180 8 p.

    Research output: Contribution to journalArticle

  197. Published

    The effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior

    Shimshoni, J. A., Dalton, E. C., Jenkins, A., Eyal, S., Ewan, K., Williams, R. S. B., Pessah, N., Yagen, B., Harwood, A. J. & Bialer, M. Mar 2007 In : Molecular Pharmacology. 71, 3, p. 884-892 9 p.

    Research output: Contribution to journalArticle

  198. Published

    A mitosome purification protocol based on percoll density gradients and its use in validating the mitosomal nature of Entamoeba histolytica mitochondrial Hsp70

    Tovar, J., Cox, S. S. E. & van der Giezen, M. 2007 In : Methods in Molecular Biology. 390, p. 167-77 11 p.

    Research output: Contribution to journalArticle

  199. Published

    APOE epsilon3 gene transfer attenuates brain damage after experimental stroke

    McColl, B. W., McGregor, A. L., Wong, A., Harris, J. D., Amalfitano, A., Magnoni, S., Baker, A. H., Dickson, G. & Horsburgh, K. 2007 In : Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 27, 3, p. 477-87 11 p.

    Research output: Contribution to journalArticle

  200. Published

    Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene

    Wishart, T. M., Macdonald, S. H., Chen, P. E., Shipston, M. J., Coleman, M. P., Gillingwater, T. H. & Ribchester, R. R. 2007 In : Molecular Neurodegeneration. 2, p. 21 1 p.

    Research output: Contribution to journalArticle

  201. Published

    Dictyostelium as a Biomedical Model

    Williams, R. 2007 Encyclopedia of Life Sciences. Boeckeler (ed.). Chichester: John Wiley & Sons, Ltd

    Research output: Chapter in Book/Report/Conference proceedingChapter

  202. Published

    Disruption of planar cell polarity signaling results in congenital heart defects and cardiomyopathy attributable to early cardiomyocyte disorganization

    Phillips, H. M., Rhee, H. J., Murdoch, J. N., Hildreth, V., Peat, J. D., Anderson, R. H., Copp, A. J., Chaudhry, B. & Henderson, D. J. 2007 In : Circulation Research. 101, 2, p. 137-145 9 p.

    Research output: Contribution to journalArticle

  203. Published

    Identification of a recurrent t(4;6) chromosomal translocation in prostate cancer

    Lane, T. M., Strefford, J. C., Yáñez-Muñoz, R. J., Purkis, P., Forsythe, E., Nia, T., Hines, J., Lu, Y. J. & Oliver, R. T. 2007 In : Journal of Urology. 177, 5, p. 1907-12 6 p.

    Research output: Contribution to journalArticle

  204. Published

    Nanobiotechnology today: focus on nanoparticles

    Soloviev, M. 2007 In : Journal of Nanobiotechnology. 5, p. 11

    Research output: Contribution to journalArticle

  205. Published

    Rapid high-resolution karyotyping with precise identification of chromosome breakpoints

    Mao, X., James, S. Y., Yáñez-Muñoz, R. J., Chaplin, T., Molloy, G., Oliver, R. T., Young, B. D. & Lu, Y. J. 2007 In : Genes Chromosomes Cancer. 46, 7, p. 675-83 9 p.

    Research output: Contribution to journalArticle

  206. Published

    Selection strategy and the design of hybrid oligonucleotide primers for RACE-PCR: cloning a family of toxin-like sequences from Agelena orientalis

    Pan, Z., Barry, R., Lipkin, A. & Soloviev, M. 2007 In : BMC Molecular Biology. 8, p. 32

    Research output: Contribution to journalArticle

  207. Published

    Skeletal muscle stem cells express anti-apoptotic ErbB receptors during activation from quiescence

    Golding, J. P., Calderbank, E., Partridge, T. A. & Beauchamp, J. R. 2007 In : Experimental cell research. 313, 2, p. 341-56 16 p.

    Research output: Contribution to journalArticle

  208. Published

    Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors

    Erreger, K., Geballe, M. T., Kristensen, A., Chen, P. E., Hansen, K. B., Lee, C. J., Yuan, H., Le, P., Lyuboslavsky, P. N., Micale, N., Jorgensen, L., Clausen, R. P., Wyllie, D. J., Snyder, J. P. & Traynelis, S. F. 2007 In : Molecular Pharmacology. 72, 4, p. 907-20 14 p.

    Research output: Contribution to journalArticle

  209. Published

    Taking the time to study competitive antagonism

    Wyllie, D. J. & Chen, P. E. 2007 In : British Journal of Pharmacology. 150, 5, p. 541-51 11 p.

    Research output: Contribution to journalArticle

  210. Published

    The Binding of Human Betacellulin to Heparin, Heparan Sulfate and Related Polysaccharides

    Mummery, R. S., Mulloy, B. & Rider, C. C. 2007 In : Glycobiology. 17, p. 1094-1103 10 p.

    Research output: Contribution to journalArticle

  211. Published

    The Major Determinant of the Heparin Binding of Glial Cell-Line Derived Neurotrophic Factor is near the Aminoterminus and is Dispensable for Receptor Binding

    Alfano, I., Vora, P., Mummery, R. S., Mulloy, B. & Rider, C. C. 2007 In : Biochemical Journal. 404, p. 131-140 10 p.

    Research output: Contribution to journalArticle

  212. 2006
  213. Published

    Water-splitting chemistry of photosystem II

    McEvoy, J. P. & Brudvig, G. W. Nov 2006 In : Chemical reviews. 106, 11, p. 4455-4483 29 p.

    Research output: Contribution to journalScientific review

  214. Published

    The neuroprotective agent, valproic acid, regulates the mitogen-activated protein kinase pathway through modulation of protein kinase A signalling in Dictyostelium discoideum

    Boeckeler, K., Adley, K., Xu, E. X., Jenkins, A., Jin, T. & Williams, R. S. B. Sep 2006 In : EUROPEAN JOURNAL OF CELL BIOLOGY. 85, 9-10, p. 1047-1057 11 p.

    Research output: Contribution to journalArticle

  215. Published

    Towards a molecular understanding of human diseases using Dictyostelium discoideum

    Williams, R. S. B., Boeckeler, K., Graef, R., Mueller-Taubenberger, A., Li, Z., Isberg, R. R., Wessels, D., Soll, D. R., Alexander, H. & Alexander, S. Sep 2006 In : Trends in Molecular Medicine. 12, 9, p. 415-424 10 p.

    Research output: Contribution to journalScientific review

  216. Published

    QM/MM models of the O-2-evolving complex of photosystem II

    Sproviero, E. M., Jose, A. G., McEvoy, J. P., Brudvig, G. W. & Batista, V. S. 11 Jul 2006 In : Journal of chemical theory and computation. 2, 4, p. 1119-1134 16 p.

    Research output: Contribution to journalScientific review

  217. Published

    The intestinal life cycle of Bacillus subtilis and close relatives

    Tam, N. K. M., Uyen, N. Q., Hong, H. A., Duc, L. H., Hoa, T. T., Serra, C. R., Henriques, A. O. & Cutting, S. M. 1 Apr 2006 In : Journal of Bacteriology. 188, 7, p. 2692-700 9 p.

    Research output: Contribution to journalArticle

  218. Published

    Characterization of synthetic oxomanganese complexes and the inorganic core of the O-2-evolving complex in photosystem - II: Evaluation of the DFT/B3LYP level of theory

    Sproviero, E. M., Gascon, J. A., McEvoy, J. P., Brudvig, G. W. & Batista, V. S. Apr 2006 In : Journal of inorganic biochemistry. 100, 4, p. 786-800 15 p.

    Research output: Contribution to journalScientific review

  219. Published

    Carotenoids present in halotolerant Bacillus spore formers

    Duc, L. H., Fraser, P. D., Tam, N. K. M. & Cutting, S. M. 1 Feb 2006 In : FEMS Microbiology Letters. 255, 2, p. 215-24 10 p.

    Research output: Contribution to journalArticle

  220. Published

    A novel mode of tangential migration of cortical projection neurons

    Britanova, O., Alifragis, P., Junek, S., Jones, K., Gruss, P. & Tarabykin, V. 2006 In : Dev Biol. 298, 1, p. 299-311 13 p.

    Research output: Contribution to journalArticle

  221. Published

    Accumulation of the inhibitory receptor EphA4 may prevent regeneration of corticospinal tract axons following lesion

    Fabes, J., Anderson, P., Yáñez-Muñoz, R. J., Thrasher, A., Brennan, C. & Bolsover, S. 2006 In : European Journal of Neuroscience. 23, 7, p. 1721-30 10 p.

    Research output: Contribution to journalArticle

  222. Published

    African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages

    Redrejo-Rodriguez, M., Garcia-Escudero, R., Yáñez-Muñoz, R. J., Salas, M. L. & Salas, J. 2006 In : J Virol. 80, 10, p. 4847-57 11 p.

    Research output: Contribution to journalArticle

  223. Published

    Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

    Montcouquiol, M., Sans, N., Huss, D., Kach, J., Dickman, J. D., Forge, A., Rachel, R. A., Copeland, N. G., Jenkins, N. A., Bogani, D., Murdoch, J., Warchol, M. E., Wenthold, R. J. & Kelley, M. W. 2006 In : The Journal of Neuroscience. 26, 19, p. 5265-5275 11 p.

    Research output: Contribution to journalArticle

  224. Published

    Conserved prefusion protein assembly in regulated exocytosis

    Rickman, C., Jiménez, J. L., Graham, M. E., Archer, D. A., Soloviev, M., Burgoyne, R. D. & Davletov, B. 2006 In : Molecular biology of the cell. 17, 1, p. 283-94 12 p.

    Research output: Contribution to journalArticle

  225. Published

    Cytokines and Proteoglycans: an introductory overview

    Mulloy, B. & Rider, C. C. 2006 In : Biochemical Society Transactions. 34, p. 409-413 5 p.

    Research output: Contribution to journalArticle

  226. Published

    Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice

    Harris, J. D., Graham, I. R., Amalfitano, A., Owen, J. S. & Dickson, G. 2006 In : GENE THERAPY AND MOLECULAR BIOLOGY. 10A, p. 17-29 13 p.

    Research output: Contribution to journalArticle

  227. Published

    Effective gene therapy with nonintegrating lentiviral vectors

    Yáñez-Muñoz, R. J., Balaggan, K. S., MacNeil, A., Howe, S. J., Schmidt, M., Smith, A. J., Buch, P., MacLaren, R. E., Anderson, P. N., Barker, S., Duran, Y., Bartholomae, C., von Kalle, C., Heckenlively, J. R., Kinnon, C., Ali, R. R. & Thrasher, A. J. 2006 In : Nature Medicine. 12, p. 348-353

    Research output: Contribution to journalArticle

  228. Published

    Enhanced immunisation and expression strategies using bacterial spores as heat-stable vaccine delivery vehicles

    Uyen, N. Q., Hong, H. A. & Cutting, S. M. 2006 In : Vaccine. 25, 2, p. 356-65 10 p.

    Research output: Contribution to journalArticle

  229. Published
  230. Published

    Evidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis

    Cox, S. S. E., van der Giezen, M., Tarr, S. J., Crompton, M. R. & Tovar, J. 2006 In : BMC Microbiology. 6, p. 45

    Research output: Contribution to journalArticle

  231. Published

    Gene therapy progress and prospects: Duchenne muscular dystrophy

    Foster, K., Foster, H. & Dickson, J. G. 2006 In : Human Gene Therapy. 13, 24, p. 1677-85 9 p.

    Research output: Contribution to journalArticle

  232. Published

    Heparin/Heparan Sulphate Binding in the TGF-? Cytokine Superfamily

    Rider, C. C. 2006 In : Biochemical Society Transactions. 34, p. 458-460 3 p.

    Research output: Contribution to journalArticle

  233. Published

    Immunization against anthrax using Bacillus subtilis spores expressing the anthrax protective antigen

    Duc, L. H., Hong, H. A., Atkins, H. S., Flick-Smith, H. C., Durrani, Z., Rijpkema, S., Titball, R. W. & Cutting, S. M. 2006 In : Vaccine. 25, 2, p. 346-55 10 p.

    Research output: Contribution to journalArticle

  234. Published

    Pax7 and myogenic progression in skeletal muscle satellite cells

    Zammit, P. S., Relaix, F., Nagata, Y., Ruiz, A. P., Collins, C. A., Partridge, T. A. & Beauchamp, J. R. 2006 In : Journal of Cell Science. 119, Pt 9, p. 1824-32 9 p.

    Research output: Contribution to journalArticle

  235. Published

    Peptidomics: bridging the gap between proteome and metabolome

    Soloviev, M. & Finch, P. 2006 In : Proteomics. 6, 3, p. 744-7 4 p.

    Research output: Contribution to journalArticle

  236. Published

    Pharmacogenetics: Defining the genetic basis of drug action and inositol trisphosphate analysis

    Adley, K. E., Williams, R. S. B. & Keim, M. 2006 Dictyostelium discoideum Protocols. Eichinger, L. & Rivero, F. (eds.). Humana Press, p. 517-534 (Methods in Molecular Biology; vol. 346)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  237. Published

    Pharmacological insights obtained from structure-function studies of ionotropic glutamate receptors

    Chen, P. E. & Wyllie, D. J. 2006 In : British Journal of Pharmacology. 147, 8, p. 839-53 15 p.

    Research output: Contribution to journalArticle

  238. Published

    Polarization and orientation of retinal ganglion cells in vivo

    Zolessi, F. R., Poggi, L., Wilkinson, C. J., Chien, C. B. & Harris, W. A. 2006 In : Neural development. 1, 2, p. 2-23 22 p.

    Research output: Contribution to journalArticle

  239. Published

    Single-channel analysis of a point mutation of a conserved serine residue in the S2 ligand-binding domain of the NR2A NMDA receptor subunit

    Wyllie, D. J., Johnston, A. R., Lipscombe, D. & Chen, P. E. 2006 In : Journal of Physiology. 574, Pt 2, p. 477-89 13 p.

    Research output: Contribution to journalArticle

  240. Published

    Smooth muscle-specific dystrophin expression improves aberrant vasoregulation in mdx mice

    Ito, K., Kimura, S., Ozasa, S., Matsukura, M., Ikezawa, M., Yoshioka, K., Ueno, H., Suzuki, M., Araki, K., Yamamura, K., Miwa, T., Dickson, G., Thomas, G. D. & Miike, T. 2006 In : Human Molecular Genetics. 15, 14, p. 2266-75 10 p.

    Research output: Contribution to journalArticle

  241. Published

    The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

    Wilkinson, C. J. & 41 others Sayer, J. A., Otto, E. A., O'Toole, J. F., Nurnberg, G., Kennedy, M. A., Becker, C., Hennies, H. C., Helou, J., Attanasio, M., Fausett, B. V., Utsch, B., Khanna, H., Liu, Y., Drummond, I., Kawakami, I., Kusakabe, T., Tsuda, M., Ma, L., Lee, H., Larson, R. G., Allen, S. J., Nigg, E. A., Shou, C., Lillo, C., Williams, D. S., Hoppe, B., Kemper, M. J., Neuhaus, T., Parisi, M. A., Glass, I. A., Petry, M., Kispert, A., Gloy, J., Ganner, A., Walz, G., Zhu, X., Goldman, D., Nurnberg, P., Swaroop, A., Leroux, M. R. & Hildebrandt, F. 2006 In : Nature Genetics. 38, 6, p. 674-81 8 p.

    Research output: Contribution to journalArticle

  242. Published

    The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells

    Gillingwater, T. H., Wishart, T. M., Chen, P. E., Haley, J. E., Robertson, K., MacDonald, S. H., Middleton, S., Wawrowski, K., Shipston, M. J., Melmed, S., Wyllie, D. J., Skehel, P. A., Coleman, M. P. & Ribchester, R. R. 2006 In : Human Molecular Genetics. 15, 4, p. 625-35 11 p.

    Research output: Contribution to journalArticle

  243. 2005
  244. Published

    The mechanism of photosynthetic water splitting

    McEvoy, J. P., Gascon, J. A., Batista, V. S. & Brudvig, G. W. Dec 2005 In : Photochemical and Photobiological Sciences. 4, 12, p. 940-949 10 p.

    Research output: Contribution to journalScientific review

  245. Published

    Cases of emesis associated with bacterial contamination of an infant breakfast cereal product

    Duc, L. H., Dong, T. C., Logan, N. A., Sutherland, A. D., Taylor, J. & Cutting, S. M. 15 Jul 2005 In : International journal of food microbiology. 102, 2, p. 245-51 7 p.

    Research output: Contribution to journalArticle

  246. Published

    Pharmacogenetics in model systems: Defining a common mechanism of action for mood stabilisers

    Williams, R. S. B. Jul 2005 In : PROGRESS IN NEURO-PSYCHOPHARMACOLOGY. 29, 6, p. 1029-1037 9 p.

    Research output: Contribution to journalScientific review

  247. Published

    GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid

    Ryves, W. J., Dalton, E. C., Harwood, A. J. & Williams, R. S. B. Jun 2005 In : Bipolar Disorders. 7, 3, p. 260-265 6 p.

    Research output: Contribution to journalArticle

  248. Published

    Direct electrochemistry of blue copper proteins at boron-doped diamond electrodes

    McEvoy, J. P. & Foord, J. S. 5 May 2005 In : Electrochimica acta. 50, 14, p. 2933-2941 9 p.

    Research output: Contribution to journalArticle

  249. Published

    Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3 beta inhibition, and viral replication: A screening approach for new bipolar disorder drugs derived from the valproic acid core structure

    Eickholt, B. J., Towers, G. J., Ryves, W. J., Eikel, D., Adley, K., Ylinen, L. M. J., Chadborn, N. H., Harwood, A. J., Nau, H. & Williams, R. S. B. May 2005 In : Molecular Pharmacology. 67, 5, p. 1426-1433 8 p.

    Research output: Contribution to journalArticle

  250. Published

    From fundamental studies of sporulation to applied spore research

    Barák, I., Ricca, E. & Cutting, S. M. 1 Jan 2005 In : Molecular microbiology. 55, 2, p. 330-8 9 p.

    Research output: Contribution to journalArticle

  251. Published

    3Li Lithium Metallotherapeutics

    Williams, R. S. B. & Harwood, A. J. 2005 Metallotherapeutic Drugs and Metal-Based Diagnostic Agents: The Use of Metals in Medicine. Gielen, M. & Tiekink, E. R. T. (eds.). Wiley-Interscience, p. 1-17 17 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  252. Published

    A novel ADP/ATP transporter in the mitosome of the microaerophilic human parasite Entamoeba histolytica

    Chan, K. W., Slotboom, D-J., Cox, S., Embley, T. M., Fabre, O., van der Giezen, M., Harding, M., Horner, D. S., Kunji, E. R. S., León-Avila, G. & Tovar, J. 2005 In : Current Biology . 15, 8, p. 737-42 6 p.

    Research output: Contribution to journalArticle

  253. Published

    Apolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient mice

    Tagalakis, A. D., Diakonov, I. A., Graham, I. R., Heald, K. A., Harris, J. D., Mulcahy, J. V., Dickson, G. & Owen, J. S. 2005 In : BBA - Gene Structure and Expression . 1686 3, p. 190-9 10 p.

    Research output: Contribution to journalArticle

  254. Published

    Characterization of chaperonin 10 (Cpn10) from the intestinal human pathogen Entamoeba histolytica

    van der Giezen, M., León-Avila, G. & Tovar, J. 2005 In : Microbiology (Reading, England). 151, Pt 9, p. 3107-15 9 p.

    Research output: Contribution to journalArticle

  255. Published

    Computational structural model of the oxygen evolving complex in photosystem II: complete ligation by protein, water and chloride

    McEvoy, J., Gascon, J. A., Sproviero, E. M., Batista, V. S. & Brudvig, G. W. 2005 Photosynthesis: Fundamental Aspects to Global Perspectives. Allen Press, p. 278-280

    Research output: Chapter in Book/Report/Conference proceedingChapter

  256. Published

    Correction of the neuropathogenic human apolipoprotein E4 (APOE4) gene to APOE3 in vitro using synthetic RNA/DNA oligonucleotides (chimeraplasts)

    Tagalakis, A. D., Dickson, J. G., Owen, J. S. & Simons, J. P. 2005 In : Journal of molecular neuroscience : MN. 25, 1, p. 95-103 9 p.

    Research output: Contribution to journalArticle

  257. Published

    Degenerate mitochondria

    van der Giezen, M. & Tovar, J. 2005 In : EMBO Reports. 6, 6, p. 525-30 6 p.

    Research output: Contribution to journalArticle

  258. Published

    Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates

    Murdoch, J. N. & 23 others Ross, A. J., May-Simera, H., Eichers, E. R., Kai, M., Hill, J., Jagger, D. J., Leitch, C. C., Chapple, J. P., Munro, P. M., Fisher, S., Tan, P. L., Phillips, H. M., Leroux, M. R., Henderson, D. J., Copp, A. J., Eliot, M. M., Lupski, J. R., Kemp, D. T., Dollfus, H., Tada, M., Katsanis, N., Forge, A. & Beales, P. L. 2005 In : Nature Genetics. 37, 10, p. 1135-1140 6 p.

    Research output: Contribution to journalArticle

  259. Published

    Langerhans cells are more efficiently transduced than dermal dendritic cells by adenovirus vectors expressing either group C or group B fibre protein: implications for mucosal vaccines

    Rozis, G., de Silva, S., Benlahrech, A., Papagatsias, T., Harris, J., Gotch, F., Dickson, G. & Patterson, S. 2005 In : European Journal of Immunology. 35, 9, p. 2617-26 10 p.

    Research output: Contribution to journalArticle

  260. Published

    Mitochondrion-derived organelles in protists and fungi

    van der Giezen, M., Tovar, J. & Clark, C. G. 2005 In : International review of cytology. 244, p. 175-225 51 p.

    Research output: Contribution to journalArticle

  261. Published

    Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1

    Ekonomou, A., Kazanis, I., Malas, S., Wood, H., Alifragis, P., Denaxa, M., Karagogeos, D., Constanti, A., Lovell-Badge, R. & Episkopou, V. 2005 In : PLoS Biology. 3, 6, p. e186

    Research output: Contribution to journalArticle

  262. Published

    Peptidomics, current status

    Soloviev, M. & Finch, P. 2005 In : Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 815, 1-2, p. 11-24 14 p.

    Research output: Contribution to journalArticle

  263. Published

    Protein import, replication, and inheritance of a vestigial mitochondrion

    Regoes, A., Zourmpanou, D., León-Avila, G., van der Giezen, M., Tovar, J. & Hehl, A. B. 2005 In : Journal of Biological Chemistry. 280, 34, p. 30557-63 7 p.

    Research output: Contribution to journalArticle

  264. Published

    Rootletin forms centriole-associated filaments and functions in centrosome cohesion

    Bahe, S., Stierhof, Y-D., Wilkinson, C. J., Leiss, F. & Nigg, E. A. 2005 In : J Cell Biol. 171, 1, p. 27-33 7 p.

    Research output: Contribution to journalArticle

  265. Published

    Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling

    Chen, P. E., Geballe, M. T., Stansfeld, P. J., Johnston, A. R., Yuan, H., Jacob, A. L., Snyder, J. P., Traynelis, S. F. & Wyllie, D. J. 2005 In : Molecular Pharmacology. 67, 5, p. 1470-84 15 p.

    Research output: Contribution to journalArticle

  266. Published

    The mechanism of photosynthetic water oxidation in the light of new structural information

    McEvoy, J. & Brudvig, G. W. 2005 Photosynthesis: Fundamental Aspects to Global Perspectives. Allen Press, p. 339-344

    Research output: Chapter in Book/Report/Conference proceedingChapter

  267. Published

    The Polo kinase Plk4 functions in centriole duplication

    Habedanck, R., Stierhof, Y-D., Wilkinson, C. J. & Nigg, E. A. 2005 In : Nature Cell Biology. 7, 11, p. 1140-6 7 p.

    Research output: Contribution to journalArticle

  268. Published

    Vangl2 Acts via RhoA Signaling to Regulate Polarized Cell Movements During Development of the Proximal Outflow Tract

    Phillips, H. M., Murdoch, J. N., Chaudhry, B., Copp, A. J. & Henderson, D. J. 2005 In : Circulation Research. 96, p. 292-299

    Research output: Contribution to journalArticle

  269. 2004
  270. Published

    Mood stabilizers and the cell biology of neuronal growth cones

    Eickholt, B. J., Williams, R. S. B. & Harwood, A. J. Dec 2004 In : Clinical Neuroscience Research. 4, 3-4, p. 189-199 11 p.

    Research output: Contribution to journalScientific review

  271. Published

    Prolyl oligopeptidase and bipolar disorder

    Williams, R. S. B. Dec 2004 In : Clinical Neuroscience Research. 4, 3-4, p. 233-242 10 p.

    Research output: Contribution to journalScientific review

  272. Published

    A molecular cell biology of lithium

    Williams, R., Ryves, W. J., Dalton, E. C., Eickholt, B., Shaltiel, G., Agam, G. & Harwood, A. J. Nov 2004 In : Biochemical Society Transactions. 32, p. 799-802 4 p.

    Research output: Contribution to journalArticle

  273. Published

    Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD)

    Athanasopoulos, T., Graham, I. R., Foster, H. & Dickson, G. Oct 2004 In : Human Gene Therapy. 11 Suppl 1, p. S109-S121 13 p.

    Research output: Contribution to journalArticle

  274. Published

    Phage display technologies

    Soloviev, M. 1 Jun 2004 In : Current Drug Discovery. JUNE, p. 25-28 4 p.

    Research output: Contribution to journalArticle

  275. Published

    Long-term expression of full-length human dystrophin in transgenic mdx mice expressing internally deleted human dystrophins

    Ferrer, A., Foster, H., Wells, K. E., Dickson, G. & Wells, D. J. Jun 2004 In : Human Gene Therapy. 11, 11, p. 884-893 10 p.

    Research output: Contribution to journalArticle

  276. Published

    Intracellular fate and immunogenicity of B. subtilis spores

    Duc, L. H., Hong, H. A., Uyen, N. Q. & Cutting, S. M. 7 May 2004 In : Vaccine. 22, 15-16, p. 1873-85 13 p.

    Research output: Contribution to journalArticle

  277. Published

    DNA-binding studies on the Bacillus subtilis transcriptional regulator and AbrB homologue, SpoVT

    Dong, T. C., Cutting, S. M. & Lewis, R. J. 15 Apr 2004 In : FEMS Microbiology Letters. 233, 2, p. 247-56 10 p.

    Research output: Contribution to journalArticle

  278. Published

    Characterization of Bacillus probiotics available for human use

    Duc, L. H., Hong, H. A., Barbosa, T. M., Henriques, A. O. & Cutting, S. M. 1 Apr 2004 In : Applied and environmental microbiology. 70, 4, p. 2161-71 11 p.

    Research output: Contribution to journalArticle

  279. Published

    Two peptidase activities decrease in treated bipolar disorder not schizophrenic patients

    Breen, G., Harwood, A. J., Gregory, K., Sinclair, M., Collier, D., St Clair, D. & Williams, R. S. B. Apr 2004 In : Bipolar Disorders. 6, 2, p. 156-161 6 p.

    Research output: Contribution to journalArticle

  280. Published

    Display of heterologous antigens on the Bacillus subtilis spore coat using CotC as a fusion partner

    Mauriello, E. M. F., Duc, L. H., Isticato, R., Cangiano, G., Hong, H. A., De Felice, M., Ricca, E. & Cutting, S. M. 12 Mar 2004 In : Vaccine. 22, 9-10, p. 1177-87 11 p.

    Research output: Contribution to journalArticle

  281. Published

    An inverse PCR technique to rapidly isolate the flanking DNA of dictyostelium insertion mutants

    Keim, M., Williams, R. S. B. & Harwood, A. J. Mar 2004 In : MOLECULAR BIOTECHNOLOGY. 26, 3, p. 221-224 4 p.

    Research output: Contribution to journalArticle

  282. Published

    Proline peptidase activities decreased in bipolar disorder not schizophrenia

    Breen, G., Harwood, A. J., Gregory, K., Sinclair, M., Collier, D., St Clair, D. & Williams, R. S. B. Mar 2004 In : EUROPEAN NEUROPSYCHOPHARMACOLOGY. 14, p. S50-S51 2 p.

    Research output: Contribution to journalArticle

  283. Published

    Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

    Krämer, A., Mailand, N., Lukas, C., Syljuåsen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J. & Lukas, J. 2004 In : Nature Cell Biology. 6, 9, p. 884-91 8 p.

    Research output: Contribution to journalArticle

  284. Published

    Dynamics and mediators of acute graft attrition after myoblast transplantation to the heart

    Suzuki, K., Murtuza, B., Beauchamp, J. R., Smolenski, R. T., Varela-Carver, A., Fukushima, S., Coppen, S. R., Partridge, T. A. & Yacoub, M. H. 2004 In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 18, 10, p. 1153-5 3 p.

    Research output: Contribution to journalArticle

  285. Published

    Glutamate receptor gating

    Erreger, K., Chen, P. E., Wyllie, D. J. & Traynelis, S. F. 2004 In : Crit Rev Neurobiol. 16, 3, p. 187-224 38 p.

    Research output: Contribution to journalArticle

  286. Published

    Heparin-binding EGF-like growth factor shows transient left-right asymmetrical expression in mouse myotome pairs

    Golding, J. P., Tsoni, S., Dixon, M., Yee, K. T., Partridge, T. A., Beauchamp, J. R., Gassmann, M. & Zammit, P. S. 2004 In : Gene expression patterns : GEP. 5, 1, p. 3-9 7 p.

    Research output: Contribution to journalArticle

  287. Published

    Influence of a threonine residue in the S2 ligand binding domain in determining agonist potency and deactivation rate of recombinant NR1a/NR2D NMDA receptors

    Chen, P. E., Johnston, A. R., Mok, M. H., Schoepfer, R. & Wyllie, D. J. 2004 In : Journal of Physiology. 558, Pt 1, p. 45-58 14 p.

    Research output: Contribution to journalArticle

  288. Published

    Lhx6 regulates the migration of cortical interneurons from the ventral telencephalon but does not specify their GABA phenotype

    Alifragis, P., Liapi, A. & Parnavelas, J. G. 2004 In : The Journal of Neuroscience. 24, 24, p. 5643-8 6 p.

    Research output: Contribution to journalArticle

  289. Published

    Mitosomes of Entamoeba histolytica are abundant mitochondrion-related remnant organelles that lack a detectable organellar genome

    León-Avila, G. & Tovar, J. 2004 In : Microbiology (Reading, England). 150, Pt 5, p. 1245-50 6 p.

    Research output: Contribution to journalArticle

  290. Published

    Mouse myotomes pairs exhibit left-right asymmetric expression of MLC3F and alpha-skeletal actin

    Golding, J. P., Partridge, T. A., Beauchamp, J. R., King, T., Brown, N. A., Gassmann, M. & Zammit, P. S. 2004 In : Developmental dynamics : an official publication of the American Association of Anatomists. 231, 4, p. 795-800 6 p.

    Research output: Contribution to journalArticle

  291. Published

    Muscle satellite cells adopt divergent fates: a mechanism for self-renewal?

    Zammit, P. S., Golding, J. P., Nagata, Y., Hudon, V., Partridge, T. A. & Beauchamp, J. R. 2004 In : The Journal of cell biology. 166, 3, p. 347-57 11 p.

    Research output: Contribution to journalArticle

  292. Published

    Myf5 expression in satellite cells and spindles in adult muscle is controlled by separate genetic elements

    Zammit, P. S., Carvajal, J. J., Golding, J. P., Morgan, J. E., Summerbell, D., Zolnerciks, J., Partridge, T. A., Rigby, P. W. J. & Beauchamp, J. R. 2004 In : Developmental Biology. 273, 2, p. 454-65 12 p.

    Research output: Contribution to journalArticle

  293. Published

    Pax7 distribution in human skeletal muscle biopsies and myogenic tissue cultures

    Reimann, J., Brimah, K., Schröder, R., Wernig, A., Beauchamp, J. R. & Partridge, T. A. 2004 In : Cell and tissue research. 315, 2, p. 233-42 10 p.

    Research output: Contribution to journalArticle

  294. Published

    Phase I study of dystrophin plasmid-based gene therapy in Duchenne/Becker muscular dystrophy

    Dickson, G. & 24 others Romero, N. B., Braun, S., Benveniste, O., Leturcq, F., Hogrel, J-Y., Morris, G. E., Barois, A., Eymard, B., Payan, C., Ortega, V., Boch, A-L., Lejean, L., Thioudellet, C., Mourot, B., Escot, C., Choquel, A., Recan, D., Kaplan, J-C., Klatzmann, D., Molinier-Frenckel, V., Guillet, J-G., Squiban, P., Herson, S. & Fardeau, M. 2004 In : Human Gene Therapy. 15, 11, p. 1065-76 12 p.

    Research output: Contribution to journalArticle

  295. Published

    Proteomic approaches to the inventory of the human centrosome

    Wilkinson, C. J., Andersen, J. S., Mann, M. & Nigg, E. A. 2004 The Centrosome in Development and Disease. Nigg, E. A. (ed.). Weinheim, Germany: Wiley VCH

    Research output: Chapter in Book/Report/Conference proceedingChapter

  296. Published

    Quantitative protein profiling using antibody arrays

    Barry, R. & Soloviev, M. 2004 In : Proteomics. 4, 12, p. 3717-26 10 p.

    Research output: Contribution to journalArticle

  297. Published

    Role of interleukin-1beta in acute inflammation and graft death after cell transplantation to the heart

    Suzuki, K., Murtuza, B., Beauchamp, J. R., Brand, N. J., Barton, P. J. R., Varela-Carver, A., Fukushima, S., Coppen, S. R., Partridge, T. A. & Yacoub, M. H. 2004 In : Circulation. 110, 11 Suppl 1, p. II219-24

    Research output: Contribution to journalArticle

  298. Published

    Structure-based mechanism of photosynthetic water oxidation

    McEvoy, J. P. & Brudvig, G. W. 2004 In : Physical Chemistry Chemical Physics. 6, 20, p. 4754-4763 10 p.

    Research output: Contribution to journalScientific review

  299. Published

    The iron-sulfur cluster assembly genes iscS and iscU of Entamoeba histolytica were acquired by horizontal gene transfer

    van der Giezen, M., Cox, S. & Tovar, J. 2004 In : BMC Evolutionary Biology. 4, p. 7

    Research output: Contribution to journalArticle

  300. Published
  301. Published

    The use of bacterial spore formers as probiotics

    Hong, H. A., Duc, L. H. & Cutting, S. M. 2004 In : FEMS Microbiology Reviews. 29, 4, p. 813-35 23 p.

    Research output: Contribution to journalArticle

  302. Published

    Towards a therapeutic inhibition of dystrophin exon 23 splicing in mdx mouse muscle induced by antisense oligoribonucleotides (splicomers): target sequence optimisation using oligonucleotide arrays

    Graham, I. R., Hill, V. J., Manoharan, M., Inamati, G. B. & Dickson, G. 2004 In : Journal of Gene Medicine. 6, 10, p. 1149-58 10 p.

    Research output: Contribution to journalArticle

  303. Published

    Transplantation of skeletal myoblasts secreting an IL-1 inhibitor modulates adverse remodeling in infarcted murine myocardium

    Murtuza, B., Suzuki, K., Bou-Gharios, G., Beauchamp, J. R., Smolenski, R. T., Partridge, T. A. & Yacoub, M. H. 2004 In : Proceedings of the National Academy of Sciences of the United States of America. 101, 12, p. 4216-21 6 p.

    Research output: Contribution to journalArticle

  304. 2003
  305. Published

    Bacterial spores as heat stable vaccine vehicles

    Duc, L. H. & Cutting, S. M. 1 Dec 2003 In : Expert Opinion on Biological Therapy. 3, 8, p. 1263-70 8 p.

    Research output: Contribution to journalArticle

  306. Published

    Germination of the spore in the gastrointestinal tract provides a novel route for heterologous antigen delivery

    Duc, L. H., Hong, H. A. & Cutting, S. M. 1 Oct 2003 In : Vaccine. 21, 27-30, p. 4215-24 10 p.

    Research output: Contribution to journalArticle

  307. Published

    SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of Pro-sigmaK in Bacillus subtilis

    Dong, T. C. & Cutting, S. M. 1 Sep 2003 In : Molecular microbiology. 49, 5, p. 1425-34 10 p.

    Research output: Contribution to journalArticle

  308. Published

    Bacterial spores as vaccine vehicles

    Duc, L. H., Hong, H. A., Fairweather, N., Ricca, E. & Cutting, S. M. 1 May 2003 In : Infection and Immunity. 71, 5, p. 2810-8 9 p.

    Research output: Contribution to journalArticle

  309. Published

    Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling

    Rudhard, Y., Kneussel, M., Nassar, M. A., Rast, G. F., Annala, A. J., Chen, P. E., Tigaret, C. M., Dean, I., Roes, J., Gibb, A. J., Hunt, S. P. & Schoepfer, R. 2003 In : The Journal of Neuroscience. 23, 6, p. 2323-32 10 p.

    Research output: Contribution to journalArticle

  310. Published

    Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization

    Oliynyk, M., Stark, C. B., Bhatt, A., Jones, M. A., Hughes-Thomas, Z. A., Wilkinson, C., Oliynyk, Z., Demydchuk, Y., Staunton, J. & Leadlay, P. F. 2003 In : Mol Microbiol. 49, 5, p. 1179-90 12 p.

    Research output: Contribution to journalArticle

  311. Published

    Combinatorial peptidomics: a generic approach for protein expression profiling

    Soloviev, M., Barry, R., Scrivener, E. & Terrett, J. 2003 In : Journal of Nanobiotechnology. 1, 1, p. 4

    Research output: Contribution to journalArticle

  312. Published

    Competitive assay formats for high-throughput affinity arrays

    Barry, R., Diggle, T., Terrett, J. & Soloviev, M. 2003 In : Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. 8, 3, p. 257-63 7 p.

    Research output: Contribution to journalArticle

  313. Published

    Dishevelled: linking convergent extension with neural tube closure

    Copp, A. J., Greene, N. D. E. & Murdoch, J. N. 2003 In : Trends in Neuroscience. 26, p. 453-455 3 p.

    Research output: Contribution to journalArticle

  314. Published

    Disruption of scribble ( Scrb1 ) causes severe neural tube defects in the circletail mouse

    Murdoch, J. N., Henderson, D. J., Doudney, K., Gaston-Massuet, C., Phillips, H. M., Paternotte, C., Arkell, R., Stanier, P. & Copp, A. J. 2003 In : Human Molecular Genetics. 12, p. 87-98 12 p.

    Research output: Contribution to journalArticle

  315. Published

    Emerging Applications of Bacterial Spores in Nanobiotechnology

    Ricca, E. & Cutting, S. M. 2003 In : Journal of Nanobiotechnology. 1, 1, p. 6

    Research output: Contribution to journalArticle

  316. Published

    Failure to generate atheroprotective apolipoprotein AI phenotypes using synthetic RNA/DNA oligonucleotides (chimeraplasts)

    Manzano, A., Mohri, Z., Sperber, G., Ogris, M., Graham, I., Dickson, G. & Owen, J. S. 2003 In : Journal of Gene Medicine. 5, 9, p. 795-802 8 p.

    Research output: Contribution to journalArticle

  317. Published

    Genomic organization and embryonic expression of Igsf8, an immunoglobulin superfamily member implicated in development of the nervous system and organ epithelia

    Murdoch, J. N., Doudney, K., Gerrelli, D., Wortham, N., Paternotte, C., Stanier, P. & Copp, A. J. 2003 In : Molecular and Cellular Neuroscience. 22, 1, p. 62-74 13 p.

    Research output: Contribution to journalArticle

  318. Published

    Mitochondrial remnant organelles of Giardia function in iron-sulphur protein maturation

    Tovar, J., León-Avila, G., Sánchez, L. B., Sutak, R., Tachezy, J., van der Giezen, M., Hernández, M., Müller, M. & Lucocq, J. M. 2003 In : Nature. 426, 6963, p. 172-6 5 p.

    Research output: Contribution to journalArticle

  319. Published

    Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse.

    Curtin, J., Quint, E., Tsipouri, V., Arkell, R., Cattanach, B., Copp, A., Henderson, D., Spurr, N., Stanier, P., Fisher, E., Nolan, P., Steel, K., Brown, S., Gray, I. & Murdoch, J. 2003 In : Current Biology. 13, p. 1-20

    Research output: Contribution to journalArticle

  320. Published

    Neuronal migration in the developing cerebral cortex: observations based on real-time imaging

    Nadarajah, B., Alifragis, P., Wong, R. O. & Parnavelas, J. G. 2003 In : Cerebral Cortex. 13, 6, p. 607-11 5 p.

    Research output: Contribution to journalArticle

  321. Published

    Novel tools for production and purification of recombinant adeno-associated viral vectors

    Harris, J. D., Beattie, S. G. & Dickson, J. G. 2003 In : Methods in molecular medicine. 76, p. 255-67 13 p.

    Research output: Contribution to journalArticle

  322. Published

    Peptidomics: A new approach to affinity protein microarrays

    Scrivener, E., Barry, R., Platt, A., Calvert, R., Masih, G., Hextall, P., Soloviev, M. & Terrett, J. 2003 In : Proteomics. 3, 2, p. 122-8 7 p.

    Research output: Contribution to journalArticle

  323. Published

    Proteomic characterization of the human centrosome by protein correlation profiling

    Andersen, J. S., Wilkinson, C. J., Mayor, T., Mortensen, P., Nigg, E. A. & Mann, M. 2003 In : Nature. 426, 6966, p. 570-4 5 p.

    Research output: Contribution to journalArticle

  324. Published

    Qu'est-ce qu'une cellule musculaire satellite?

    Mouly, V. & Beauchamp, J. 2003 In : Médecine sciences : M/S. 19, 6-7, p. 696

    Research output: Contribution to journalArticle

  325. Published

    Restricted expression of Slap-1 in the rodent cerebral cortex

    Alifragis, P., Molnar, Z. & Parnavelas, J. G. 2003 In : Gene Expr Patterns. 3, 4, p. 437-40 4 p.

    Research output: Contribution to journalArticle

  326. Published

    Self-assembly of proteins and their nucleic acids

    Fletcher, G., Mason, S., Terrett, J. & Soloviev, M. 2003 In : Journal of Nanobiotechnology. 1, 1, p. 1

    Research output: Contribution to journalArticle

  327. Published

    Tangential migration of cells from the basal to the dorsal telencephalic regions in the chick

    Tuorto, F., Alifragis, P., Failla, V., Parnavelas, J. G. & Gulisano, M. 2003 In : European Journal of Neuroscience. 18, 12, p. 3388-93 6 p.

    Research output: Contribution to journalArticle

  328. Published

    The Binding of Human Glial Cell-Line Derived Neurotrophic Factor (GDNF) to Heparin and Heparan Sulphate: Importance of 2-O-Sulphate Groups and Effects on its Interaction with its Receptor GFR?1

    Rickard, S. M., Mummery, R. S., Mulloy, B. & Rider, C. C. 2003 In : Glycobiology. 13, p. 419-426 8 p.

    Research output: Contribution to journalArticle

  329. Published

    The genetic basis of mammalian neurulation

    Copp, A. J., Greene, N. D. & Murdoch, J. N. 2003 In : Nature Reviews Genetics. 4, 10, p. 784-793 10 p.

    Research output: Contribution to journalArticle

  330. Published

    The Interaction between Glial Cell-line Derived Neurotrophic Factor (GDNF) and 2-O-Sulphated Heparin-Related Glycosaminoglycans

    Rider, C. C. 2003 In : Biochemical Society Transactions. 31, p. 337-339 3 p.

    Research output: Contribution to journalArticle

  331. Published

    Two modes of recruitment of E(spl) repressors onto target genes

    Giagtzoglou, N., Alifragis, P., Koumbanakis, K. A. & Delidakis, C. 2003 In : Social Development. 130, 2, p. 259-70 12 p.

    Research output: Contribution to journalArticle

  332. 2002
  333. Published

    Recombinant micro-genes and dystrophin viral vectors

    Dickson, G., Roberts, M. L., Wells, D. J. & Fabb, S. A. Oct 2002 In : Neuromuscular Disorders. 12, p. S40-S44 5 p.

    Research output: Contribution to journalArticle

  334. Published

    Screening for antisense modulation of dystrophin pre-mRNA splicing

    Dickson, G., Hill, V. & Graham, I. R. Oct 2002 In : Neuromuscular Disorders. 12, p. S67-S70 4 p.

    Research output: Contribution to journalArticle

  335. Published

    Loss of the beta-catenin homologue aardvark causes ectopic stalk formation in Dictyostelium

    Coates, J. C., Grimson, M. J., Williams, R. S. B., Bergman, W., Blanton, R. L. & Harwood, A. J. Aug 2002 In : MECHANISMS OF DEVELOPMENT. 116, 1-2, p. 117-127 11 p.

    Research output: Contribution to journalArticle

  336. Published

    A common mechanism of action for three mood-stabilizing drugs

    Williams, R. S. B., Cheng, L. L., Mudge, A. W. & Harwood, A. J. 16 May 2002 In : Nature. 417, 6886, p. 292-295 4 p.

    Research output: Contribution to journalArticle

  337. Published

    Bacillus probiotics: spore germination in the gastrointestinal tract

    Casula, G. & Cutting, S. M. 1 May 2002 In : Applied and environmental microbiology. 68, 5, p. 2344-52 9 p.

    Research output: Contribution to journalArticle

  338. Published

    Insights into gated electron-transfer kinetics at the electrode-protein interface: A square wave voltammetry study of the blue copper protein azurin

    Jeuken, L. J. C., McEvoy, J. P. & Armstrong, F. A. 7 Mar 2002 In : Journal of Physical Chemistry B. 106, 9, p. 2304-2313 10 p.

    Research output: Contribution to journalArticle

  339. Published

    Crystal structures of ferredoxin variants exhibiting large changes in [Fe-S] reduction potential

    Chen, K. S., Bonagura, C. A., Tilley, G. J., McEvoy, J. P., Jung, Y. S., Armstrong, F. A., Stout, C. D. & Burgess, B. K. Mar 2002 In : Nature structural biology. 9, 3, p. 188-192 5 p.

    Research output: Contribution to journalArticle

  340. Published

    Identification of the Axin and Frat binding region of glycogen synthase kinase-3

    Fraser, E., Young, N., Dajani, R., Franca-Koh, J., Ryves, J., Williams, R. S. B., Yeo, M., Webster, M. T., Richardson, C., Smalley, M. J., Pearl, L. H., Harwood, A. & Dale, T. C. 18 Jan 2002 In : Journal of Biological Chemistry. 277, 3, p. 2176-2185 10 p.

    Research output: Contribution to journalArticle

  341. Published

    The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases

    Hoa, N. T., Brannigan, J. A. & Cutting, S. M. 1 Jan 2002 In : Journal of Bacteriology. 184, 1, p. 191-9 9 p.

    Research output: Contribution to journalArticle

  342. Published

    Inhibition of atherosclerosis in apolipoprotein-E-deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E

    Harris, J. D., Schepelmann, S., Athanasopoulos, T., Graham, I. R., Stannard, A. K., Mohri, Z., Hill, V., Hassall, D. G., Owen, J. S. & Dickson, G. Jan 2002 In : Human Gene Therapy. 9, 1, p. 21-29 9 p.

    Research output: Contribution to journalArticle

  343. Published

    A chromosomal position effect on gene targeting in human cells

    Yáñez, R. J. & Porter, A. C. G. 2002 In : Nucleic Acids Research. 30, p. 4892-4901 10 p.

    Research output: Contribution to journalArticle

  344. Published

    A novel method of labeling and characterizing migrating neurons in the developing central nervous system

    Alifragis, P., Parnavelas, J. G. & Nadarajah, B. 2002 In : Exp Neurol. 174, 2, p. 259-65 7 p.

    Research output: Contribution to journalArticle

  345. Published

    Acute regression of advanced and retardation of early aortic atheroma in immunocompetent apolipoprotein-E (apoE) deficient mice by administration of a second generation [E1(-), E3(-), polymerase(-)] adenovirus vector expressing human apoE

    Harris, J. D., Graham, I. R., Schepelmann, S., Stannard, A. K., Roberts, M. L., Hodges, B. L., Hill, V., Amalfitano, A., Hassall, D. G., Owen, J. S. & Dickson, G. 2002 In : Human Molecular Genetics. 11, 1, p. 43-58 16 p.

    Research output: Contribution to journalArticle

  346. Published

    Adeno-associated virus vector gene transfer and sarcolemmal expression of a 144 kDa micro-dystrophin effectively restores the dystrophin-associated protein complex and inhibits myofibre degeneration in nude/mdx mice

    Fabb, S. A., Wells, D. J., Serpente, P. & Dickson, G. 2002 In : Human Molecular Genetics. 11, 7, p. 733-41 9 p.

    Research output: Contribution to journalArticle

  347. Published

    Cloning and characterization of Igsf9 in mouse and human: a new member of the immunoglobulin superfamily expressed in the developing nervous system

    Doudney, K., Murdoch, J. N., Braybrook, C., Paternotte, C., Bentley, L., Copp, A. J. & Stanier, P. 2002 In : Genomics. 79, 5, p. 663-670 8 p.

    Research output: Contribution to journalArticle

  348. Published

    Developments in gene-based therapy for muscular dystrophy

    Dunckley, M. G. & Dickson, G. 2002 Methods in Molecular Medicine - Muscular Dystrophy. Walker, Anderson & B. (eds.). Humana Press

    Research output: Chapter in Book/Report/Conference proceedingChapter

  349. Published

    Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line

    Yáñez, R. J. & Porter, A. C. G. 2002 In : Nucleic Acids Research. 30, 3, p. 740-8 9 p.

    Research output: Contribution to journalArticle

  350. Published

    Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase

    Long, P. F., Wilkinson, C. J., Bisang, C. P., Cortés, J., Dunster, N., Oliynyk, M., McCormick, E., McArthur, H., Mendez, C., Salas, J. A., Staunton, J. & Leadlay, P. F. 2002 In : Mol Microbiol. 43, 5, p. 1215-25 11 p.

    Research output: Contribution to journalArticle

  351. Published

    Gene repair and mutagenesis mediated by chimeric RNA-DNA oligonucleotides: chimeraplasty for gene therapy and conversion of single nucleotide polymorphisms (SNPs)

    Graham, I. R. & Dickson, G. 2002 In : BBA - Gene Structure and Expression . 1587, 1, p. 1-6 6 p.

    Research output: Contribution to journalArticle

  352. Published

    Increasing the efficiency of heterologous promoters in actinomycetes

    Wilkinson, C. J., Hughes-Thomas, Z. A., Martin, C. J., Böhm, I., Mironenko, T., Deacon, M., Wheatcroft, M., Wirtz, G., Staunton, J. & Leadlay, P. F. 2002 In : J Mol Microbiol Biotechnol. 4, 4, p. 417-26 10 p.

    Research output: Contribution to journalArticle

  353. Published

    Kinetics of myoblast proliferation show that resident satellite cells are competent to fully regenerate skeletal muscle fibers

    Zammit, P. S., Heslop, L., Hudon, V., Rosenblatt, J. D., Tajbakhsh, S., Buckingham, M. E., Beauchamp, J. R. & Partridge, T. A. 2002 In : Experimental cell research. 281, 1, p. 39-49 11 p.

    Research output: Contribution to journalArticle

  354. Published

    Micro-dystrophin cDNA ameliorates dystrophic phenotypes when introduced into mdx mice as a transgene

    Sakamoto, M., Yuasa, K., Yoshimura, M., Yokota, T., Ikemoto, T., Suzuki, M., Dickson, G., Miyagoe-Suzuki, Y. & Takeda, S. 2002 In : BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 293, 4, p. 1265-72 8 p.

    Research output: Contribution to journalArticle

  355. Published

    Myogenic cell proliferation and generation of a reversible tumorigenic phenotype are triggered by preirradiation of the recipient site

    Morgan, J. E., Gross, J. G., Pagel, C. N., Beauchamp, J. R., Fassati, A., Thrasher, A. J., Di Santo, J. P., Fisher, I. B., Shiwen, X., Abraham, D. J. & Partridge, T. A. 2002 In : The Journal of cell biology. 157, 4, p. 693-702 10 p.

    Research output: Contribution to journalArticle

  356. Published

    Production of recombinant adeno-associated virus

    Harris, J., Beattie, S. & Dickson, G. 2002 Methods in Molecular Medicine - Gene Therapy. Walker, J. (ed.). Humana Press

    Research output: Chapter in Book/Report/Conference proceedingChapter

  357. Published

    Skipping in a hybrid polyketide synthase. Evidence for ACP-to-ACP chain transfer

    Thomas, I., Martin, C. J., Wilkinson, C. J., Staunton, J. & Leadlay, P. F. 2002 In : Chemistry and Biology. 9, 7, p. 781-7 7 p.

    Research output: Contribution to journalArticle

  358. Published

    Spatial learning is unimpaired in mice containing a deletion of the alpha-synuclein locus

    Chen, P. E., Specht, C. G., Morris, R. G. & Schoepfer, R. 2002 In : European Journal of Neuroscience. 16, 1, p. 154-8 5 p.

    Research output: Contribution to journalArticle

  359. Published

    Stable micro-dystrophin gene transfer using an integrating adeno-retroviral hybrid vector ameliorates the dystrophic pathology in mdx mouse muscle

    Roberts, M. L., Wells, D. J., Graham, I. R., Fabb, S. A., Hill, V. J., Duisit, G., Yuasa, K., Takeda, S., Cosset, F-L. & Dickson, G. 2002 In : Human Molecular Genetics. 11, 15, p. 1719-30 12 p.

    Research output: Contribution to journalArticle

  360. Published

    The future of Duchenne muscular dystrophy gene therapy: shrinking the dystrophin gene

    Roberts, M. & Dickson, G. 2002 In : Current opinion in molecular therapeutics. 4, 4, p. 343-8 6 p.

    Research output: Contribution to journalArticle

  361. Published

    The origin and migration of cortical neurons

    Parnavelas, J. G., Alifragis, P. & Nadarajah, B. 2002 In : Prog Brain Res. 136, p. 73-80 8 p.

    Research output: Contribution to journalArticle

  362. Published

    Ventricle-directed migration in the developing cerebral cortex

    Nadarajah, B., Alifragis, P., Wong, R. O. & Parnavelas, J. G. 2002 In : Nature Neuroscience. 5, 3, p. 218-24 7 p.

    Research output: Contribution to journalArticle

  363. 2001
  364. Published

    The skeletal muscle satellite cell: stem cell or son of stem cell?

    Zammit, P. S. & Beauchamp, J. R. Oct 2001 In : Differentiation. 68, 4-5, p. 193-204 12 p.

    Research output: Contribution to journalScientific review

  365. Published

    The short RRKK motif from the metabotropic glutamate receptor 1B C-terminus confers endoglycosidase H sensitivity and endoplasmic reticulum retention to the mGluR1B unrelated transmembrane proteins

    Soloviev, M. M., Chan, W. Y. & McIlhinney, R. A. J. Sep 2001 In : Journal of neurochemistry. 78, p. 185-185 1 p.

    Research output: Contribution to journalArticle

  366. Published

    Oligonucleotide-based gene correction strategies: Applications to neuromuscular and cardiovascular diseases

    Graham, I. R., Beattie, S. G., Hill, V. J. & Dickson, G. Aug 2001 In : CROATIAN MEDICAL JOURNAL. 42, 4, p. 467-472 6 p.

    Research output: Contribution to journalArticle

  367. Published

    Gene repair validation

    Graham, I. R., Manzano, A., Tagalakis, A. D., Mohri, Z., Sperber, G., Hill, V., Beattie, S., Schepelmann, S., Dickson, G. & Owen, J. S. Jun 2001 In : Nature biotechnology. 19, 6, p. 507-508 2 p.

    Research output: Contribution to journalLetter

  368. Published

    The role of protein-protein interactions in the targeting of metabotropic glutamate receptors

    McIlhinney, R. A. J., Chan, W. Y., Soloviev, M. M. & Cirulea, F. May 2001 In : British Journal of Pharmacology. 133, p. U133-U133 1 p.

    Research output: Contribution to journalArticle

  369. Published

    Transplanted primary neonatal myoblasts can give rise to functional satellite cells as identified using the Myf5(nlacZ/+) mouse

    Heslop, L., Beauchamp, J. R., Tajbakhsh, S., Buckingham, M. E., Partridge, T. A. & Zammit, P. S. May 2001 In : Human Gene Therapy. 8, 10, p. 778-783 6 p.

    Research output: Contribution to journalArticle

  370. Published

    Adenosine-glutamate receptor-receptor interactions in the central nervous system

    Ciruela, F., Escriche, M., Soloviev, M. M., Canela, E. I., Burgeno, J., Mallol, J., Chan, W. Y., Lluis, C., McIlhinney, R. A. & Franco, R. 2001 In : DRUG DEVELOPMENT RESEARCH. 52, 1-2, p. 316-322 7 p.

    Research output: Contribution to journalArticle

  371. Published

    Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

    Bamforth, S. D., Braganca, J., Eloranta, J. J., Murdoch, J. N., Marques, F. I., Kranc, K. R., Farza, H., Henderson, D. J., Hurst, H. C. & Bhattacharya, S. 2001 In : Nature Genetics. 29, 4, p. 469-74 6 p.

    Research output: Contribution to journalArticle

  372. Published

    Cardiovascular defects associated with abnormalities in midline development in the loop-tail mouse mutant

    Henderson, D. J., Conway, S. J., Greene, N. D. E., Gerrelli, D., Murdoch, J. N., Anderson, R. H. & Copp, A. J. 2001 In : Circulation Research. 89, p. 6-12 7 p.

    Research output: Contribution to journalArticle

  373. Published

    Cell-derived apolipoprotein E (ApoE) particles inhibit vascular cell adhesion molecule-1 (VCAM-1) expression in human endothelial cells

    Stannard, A. K., Riddell, D. R., Sacre, S. M., Tagalakis, A. D., Langer, C., von Eckardstein, A., Cullen, P., Athanasopoulos, T., Dickson, G. & Owen, J. S. 2001 In : Journal of Biological Chemistry. 276, 49, p. 46011-6 6 p.

    Research output: Contribution to journalArticle

  374. Published

    Chain initiation on the soraphen-producing modular polyketide synthase from Sorangium cellulosum

    Wilkinson, C. J., Frost, E. J., Staunton, J. & Leadlay, P. F. 2001 In : Chemistry and Biology. 8, 12, p. 1197-208 12 p.

    Research output: Contribution to journalArticle

  375. Published

    Circletail , a new mouse mutant with severe neural tube defects: Chromosomal localization and interaction with the loop-tail mutation

    Murdoch, J. N., Rachel, R. A., Shah, S., Beermann, F., Stanier, P., Mason, C. A. & Copp, A. J. 2001 In : Genomics. 78, p. 55-63 9 p.

    Research output: Contribution to journalArticle

  376. Published

    Comparative physical and transcript maps of ~1 Mb around loop- tail, a gene for severe neural tube defects on distal mouse Chromosome 1 and human chromosome 1q22-q23

    Doudney, K., Murdoch, J. N., Paternotte, C., Bentley, L., Gregory, S., Copp, A. J. & Stanier, P. 2001 In : Genomics. 72, p. 180-192 13 p.

    Research output: Contribution to journalArticle

  377. Published

    Engineering of complex polyketide biosynthesis--insights from sequencing of the monensin biosynthetic gene cluster

    Leadlay, P. F., Staunton, J., Oliynyk, M., Bisang, C., Cortés, J., Frost, E., Hughes-Thomas, Z. A., Jones, M. A., Kendrew, S. G., Lester, J. B., Long, P. F., McArthur, H. A., McCormick, E. L., Oliynyk, Z., Stark, C. B. & Wilkinson, C. J. 2001 In : J Ind Microbiol Biotechnol. 27, 6, p. 360-7 8 p.

    Research output: Contribution to journalArticle

  378. Published

    EuroBiochips: spot the difference!

    Soloviev, M. 2001 In : Drug discovery today. 6, 15, p. 775-777 3 p.

    Research output: Contribution to journalArticle

  379. Published

    Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty

    Tagalakis, A. D., Graham, I. R., Riddell, D. R., Dickson, J. G. & Owen, J. S. 2001 In : Journal of Biological Chemistry. 276, 16, p. 13226-30 5 p.

    Research output: Contribution to journalArticle

  380. Published

    Metabotropic glutamate 1alpha and adenosine A1 receptors assemble into functionally interacting complexes

    Ciruela, F., Escriche, M., Burgueno, J., Angulo, E., Casado, V., Soloviev, M. M., Canela, E. I., Mallol, J., Chan, W. Y., Lluis, C., McIlhinney, R. A. & Franco, R. 2001 In : Journal of Biological Chemistry. 276, 21, p. 18345-51 7 p.

    Research output: Contribution to journalArticle

  381. Published

    Molecular Cell Biology of Muscle - Principles and Disease Correlates

    Brown, S. C., Walsh, F. S. & Dickson, G. 2001 Disorders of Voluntary Muscle. Karpati, Griggs & Hilton-Jones (eds.). CUP

    Research output: Chapter in Book/Report/Conference proceedingChapter

  382. Published

    Molecular determinants of metabotropic glutamate receptor 1B trafficking

    Chan, W. Y., Soloviev, M. M., Ciruela, F. & McIlhinney, R. A. 2001 In : Molecular and cellular neurosciences. 17, 3, p. 577-88 12 p.

    Research output: Contribution to journalArticle

  383. Published

    Post-mitotic, differentiated myotubes efficiently produce retroviral vector from hybrid adeno-retrovirus templates

    Roberts, M. L., Athanasopoulos, T., Pohlschmidt, M., Duisit, G., Cosset, F. L. & Dickson, G. 2001 In : Human Gene Therapy. 8, 20, p. 1580-6 7 p.

    Research output: Contribution to journalArticle

  384. Published

    Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification

    Murdoch, J. N., Doudney, K., Paternotte, C., Copp, A. J. & Stanier, P. 2001 In : Human Molecular Genetics. 10, p. 2593-2601 9 p.

    Research output: Contribution to journalArticle

  385. 2000
  386. Published

    Role of the surface-exposed and copper-coordinating histidine in blue copper proteins: The electron-transfer and redox-coupled ligand binding properties of His117Gly azurin

    Jeuken, L. J. C., van Vliet, P., Verbeet, M. P., Camba, R., McEvoy, J. P., Armstrong, F. A. & Canters, G. W. 13 Dec 2000 In : Journal of the American Chemical Society. 122, 49, p. 12186-12194 9 p.

    Research output: Contribution to journalArticle

  387. Published

    Expression of CD34 and Myf5 defines the majority of quiescent adult skeletal muscle satellite cells

    Beauchamp, J. R., Heslop, L., Yu, D. S. W., Tajbakhsh, S., Kelly, R. G., Wernig, A., Buckingham, M. E., Partridge, T. A. & Zammit, P. S. 11 Dec 2000 In : The Journal of cell biology. 151, 6, p. 1221-1233 13 p.

    Research output: Contribution to journalArticle

  388. Published

    Intramuscular injection of a plasmid vector expressing human apolipoprotein E limits progression of xanthoma and aortic atheroma in apoE-deficient mice

    Athanasopoulos, T., Owen, J. S., Hassall, D., Dunckley, M. G., Drew, J., Goodman, J., Tagalakis, A. D., Riddell, D. R. & Dickson, G. 12 Oct 2000 In : Human Molecular Genetics. 9, 17, p. 2545-2551 7 p.

    Research output: Contribution to journalArticle

  389. Published

    Autocrine overexpression of CTGF maintains fibrosis: RDA analysis of fibrosis genes in systemic sclerosis

    Shi-Wen, X., Pennington, D., Holmes, A., Leask, A., Bradham, D., Beauchamp, J. R., Fonseca, C., du Bois, R. M., Martin, G. R., Black, C. M. & Abraham, D. J. 25 Aug 2000 In : Experimental cell research. 259, 1, p. 213-224 12 p.

    Research output: Contribution to journalArticle

  390. Published

    Markers of satellite cell behaviour during muscle regeneration

    Morgan, J., Gross, J., Blaveri, K., Heslop, L., Beauchamp, J., Zammit, P., Lu, Q., Yu, D., Rosenblatt, D. & Partridg, T. 15 Mar 2000 In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 14, 4, p. A799-A799 1 p.

    Research output: Contribution to journalArticle

  391. Published

    Lithium therapy and signal transduction

    Williams, R. S. B. & Harwood, A. J. Feb 2000 In : TRENDS IN PHARMACOLOGICAL SCIENCES. 21, 2, p. 61-64 4 p.

    Research output: Contribution to journalArticle

  392. Published

    Characterization of the Heparin Binding Properties of Interleukin 6

    Mummery, R. & Rider, C. C. 2000 In : Journal of Immunology. 165, p. 5671-5679 9 p.

    Research output: Contribution to journalArticle

  393. Published

    Detection of a surface-exposed PEST like sequence in the metabotropic glutamate receptor mGluR1 alpha

    Soloviev, M. M. 2000 In : Bioinformatics. 16, 9, p. 837-8 2 p.

    Research output: Contribution to journalArticle

  394. Published

    Fast voltammetric studies of the kinetics and energetics of coupled electron-transfer reactions in proteins

    Armstrong, F. A., Camba, R., Heering, H. A., Hirst, J., Jeuken, L. J. C., Jones, A. K., Leger, C. & McEvoy, J. P. 2000 In : Faraday Discussions. 116, p. 191-203 13 p.

    Research output: Contribution to journalArticle

  395. Published

    Gene therapy vectors based on adeno-associated virus: characteristics and applications to acquired and inherited diseases (review)

    Athanasopoulos, T., Fabb, S. & Dickson, G. 2000 In : INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 6, 4, p. 363-375 13 p.

    Research output: Contribution to journalScientific review

  396. Published

    Homer-1c/Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type 1alpha: evidence for an anchoring function

    Ciruela, F., Soloviev, M. M., Chan, W. Y. & McIlhinney, R. A. 2000 In : Molecular and cellular neurosciences. 15, 1, p. 36-50 15 p.

    Research output: Contribution to journalArticle

  397. Published

    Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing

    Soloviev, M. M., Ciruela, F., Chan, W. Y. & McIlhinney, R. A. 2000 In : Journal of molecular biology. 295, 5, p. 1185-200 16 p.

    Research output: Contribution to journalArticle

  398. Published

    Mouse brain and muscle tissues constitutively express high levels of Homer proteins

    Soloviev, M. M., Ciruela, F., Chan, W. Y. & McIlhinney, R. A. 2000 In : European journal of biochemistry / FEBS. 267, 3, p. 634-9 6 p.

    Research output: Contribution to journalArticle

  399. Published

    Retinal axon misrouting at the optic chiasm in mice with neural tube closure defects

    Rachel, R. A., Murdoch, J. N., Beermann, F., Copp, A. J. & Mason, C. A. 2000 In : Genesis.27, 1, p. 32-47 16 p.

    Research output: Contribution to journalArticle

  400. Published

    RNA viruses as gene therapy vectors

    Usmani, B., Fassati, A. & Dickson, G. 2000 Practical Approaches in Molecular Biology: the RNA Viruses. Cann, A. J. (ed.). OUP

    Research output: Chapter in Book/Report/Conference proceedingChapter

  401. Published

    Technology evaluation: AAV factor IX gene therapy, Avigen Inc

    Fabb, S. A. & Dickson, J. G. 2000 In : Current opinion in molecular therapeutics. 2, 5, p. 601-6 6 p.

    Research output: Contribution to journalArticle

  402. Published

    The Binding of Interleukin 12 to Heparin and Heparan Sulphate

    Garnier, P. C., Gibbs, R. V. & Rider, C. C. 2000 In : Immunology Letters. 73, p. 103 1 p.

    Research output: Contribution to journalArticle

  403. Published

    The Binding of the Th-1-Stimulatory Cytokine IL-12 to Heparin and Heparan Sulphate

    Garnier, P. C., Gibbs, R. V. & Rider, C. C. 2000 18th International Congress of Biochemistry and Molecular Biology Abstracts. p. 480 1 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  404. Published

    The C-terminal domain of the metabotropic glutamate receptors mGLUR1A and mGLUR1B regulate their intracellular targeting.

    Chan, W. Y., Ciruela, F., Soloviev, M. M. & Mellhinney, R. A. J. 2000 In : European Journal of Neuroscience. 12, p. 462-462 1 p.

    Research output: Contribution to journalSpecial issue

  405. Published

    Uracil incorporation into a gene targeting construct reduces the frequency of homologous and nonhomologous recombinants in human cells

    Yáñez, R. J. & Porter, A. C. G. 2000 In : Mutat Res. 461, 2, p. 157-62 6 p.

    Research output: Contribution to journalArticle

  406. 1999
  407. Published

    Construction and characterization of polycistronic retrovirus vectors for sustained and high-level co-expression of apolipoprotein A-I and lecithin-cholesterol acyltransferase

    Fan, L. M., Owen, J. S. & Dickson, G. Nov 1999 In : Atherosclerosis. 147, 1, p. 139-145 7 p.

    Research output: Contribution to journalArticle

  408. Published

    Function and co-expression of a metabotropic glutamate receptor 5-green fluorescent protein fusion (mGluR5-GFP) with Homer-1a and Homer-1c

    Coutinho, V., Ciruela, F., Soloviev, M. M., Tones, M. A. & Henley, J. M. Oct 1999 In : Neuropharmacology. 38, 10, p. A12-A13 2 p.

    Research output: Contribution to journalSpecial issue

  409. Published

    Protein film cryovoltammetry: demonstrations with a 7Fe ([3Fe-4S]+[4Fe-4S]) ferredoxin

    McEvoy, J. P. & Armstrong, F. A. 7 Sep 1999 In : J. Chem. Soc., Chemical Communications. 17, p. 1635-1636 2 p.

    Research output: Contribution to journalArticle

  410. Published

    Enhanced expression of recombinant dystrophin following intramuscular injection of Epstein-Barr virus (EBV)-based mini-chromosome vectors in mdx mice

    Tsukamoto, H., Wells, D. J., Brown, S. C., Serpente, P., Strong, P. N., Drew, J., Inui, K., Okada, S. & Dickson, G. Jul 1999 In : Human Gene Therapy. 6, 7, p. 1331-1335 5 p.

    Research output: Contribution to journalArticle

  411. Published

    Loss of a prolyl oligopeptidase confers resistance to lithium by elevation of inositol (1,4,5) trisphosphate

    Williams, R. S. B., Eames, M., Ryves, W. J., Viggars, J. & Harwood, A. J. 17 May 1999 In : EMBO Journal . 18, 10, p. 2734-2745 12 p.

    Research output: Contribution to journalArticle

  412. Published

    Encapsulation of recombinant cells expressing apolipoprotein E (apo E): A gene transfer approach for hyperlipidaemia

    Tagalakis, A. D., Vinogradov, D. V., Heald, K. A., Dickson, J. G. & Owen, J. S. May 1999 In : Atherosclerosis. 144, p. 105-106 2 p.

    Research output: Contribution to journalArticle

  413. Published

    Gene therapy for atherosclerosis: A comparative study of adeno-associated virus (AAV) and conventional plasmid vectors encoding human apolipopoprotein E (apoE) cDNAs

    Athanasopoulos, P. T., Dunckley, M. G., Hassall, D. G., Fabb, S., Tagalakis, A. D., Shepelmann, S., Owen, J. & Dickson, J. G. May 1999 In : Atherosclerosis. 144, p. 93-94 2 p.

    Research output: Contribution to journalArticle

  414. Published

    Locally secreted apolipoprotein (apo)E inhibits vascular cell adhesion molecule-1 (VCAM-1) expression in human endothelial cells

    Stannard, A. K., Riddell, D. R., Tagalakis, A. D., Athanasopoulos, T., Dickson, J. G. & Owen, J. S. May 1999 In : Atherosclerosis. 144, p. 86-86 1 p.

    Research output: Contribution to journalArticle

  415. Published

    Muscle-based expression of antiatherogenic high density lipoprotein components using recombinant adeno-associated virus based vectors

    Athanasopoulos, P. T., Schepelmann, S., Fan, L., Hassall, D. G., Fabb, S., Owen, J. & Dickson, J. G. May 1999 In : Atherosclerosis. 144, p. 168-168 1 p.

    Research output: Contribution to journalArticle

  416. Published

    Dynamics of myoblast transplantation reveal a discrete minority of precursors with stem cell-like properties as the myogenic source

    Beauchamp, J. R., Morgan, J. E., Pagel, C. N. & Partridge, T. A. 22 Mar 1999 In : The Journal of cell biology. 144, 6, p. 1113-22 10 p.

    Research output: Contribution to journalArticle

  417. Published

    Cloning and characterization of a eukaryotic pantothenate kinase gene (panK) from Aspergillus nidulans

    Calder, R. B., Williams, R. S. B., Ramaswamy, G., Rock, C. O., Campbell, E., Unkles, S. E., Kinghorn, J. R. & Jackowski, S. 22 Jan 1999 In : Journal of Biological Chemistry. 274, 4, p. 2014-2020 7 p.

    Research output: Contribution to journalArticle

  418. Published

    Cationic lipids and polymers are able to enhance adenoviral infection of cultured mouse myotubes

    Dodds, E., Piper, T. A., Murphy, S. J. & Dickson, G. 1999 In : Journal of neurochemistry. 72, 5, p. 2105-12 8 p.

    Research output: Contribution to journalArticle

  419. Published

    Cell engineering for muscle gene therapy: Extemporaneous production of retroviral vector packaging macrophages using defective herpes simplex virus type 1 vectors harbouring gag, pol, env genes

    Parrish, E., Peltekian, E., Dickson, G., Epstein, A. L. & Garcia, L. 1999 In : CYTOTECHNOLOGY. 30, 1-3, p. 173-180 8 p.

    Research output: Contribution to journalArticle

  420. Published

    Cell surface expression of the metabotropic glutamate receptor type 1alpha is regulated by the C-terminal tail

    Ciruela, F., Soloviev, M. M. & McIlhinney, R. A. 1999 In : FEBS Letters. 448, 1, p. 91-4 4 p.

    Research output: Contribution to journalArticle

  421. Published

    Co-expression of metabotropic glutamate receptor type 1alpha with homer-1a/Vesl-1S increases the cell surface expression of the receptor

    Ciruela, F., Soloviev, M. M. & McIlhinney, R. A. 1999 In : Biochemical journal. 341 ( Pt 3), p. 795-803 9 p.

    Research output: Contribution to journalArticle

  422. Published

    Dystrophic phenotype induced in vitro by antibody blockade of muscle alpha-dystroglycan-laminin interaction

    Brown, S. C., Fassati, A., Popplewell, L., Page, A. M., Henry, M. D., Campbell, K. P. & Dickson, G. 1999 In : Journal of Cell Science. 112 ( Pt 2), p. 209-16 8 p.

    Research output: Contribution to journalArticle

  423. Published

    Gene targeting is enhanced in human cells overexpressing hRAD51

    Yáñez, R. J. & Porter, A. C. G. 1999 In : Gene Therapy. 6, p. 1282-1290 9 p.

    Research output: Contribution to journalArticle

  424. Published

    Gene Therapy Approaches to Muscular Dystrophies

    Murphy, S. & Dickson, G. 1999 Gene Therapy Technologies and Regulations: From Laboratory to Clinic. Meager, T. (ed.). Wiley-Blackwell

    Research output: Chapter in Book/Report/Conference proceedingChapter

  425. Published

    Homer-1c/Vesl-1L modulate the cell surface targeting of metabotropic glutamate receptor type 1 alpha

    Ciruela, F., Soloviev, M. M., Chan, W. Y. & McIlhinney, R. A. J. 1999 In : Journal of neurochemistry. 73, p. S140-S140 1 p.

    Research output: Contribution to journalSpecial issue

  426. Published

    Identification of expression of the metabotropic glutamate receptor type 1 and of the associated Homer/Vesl proteins in a mammalian skeletal muscle

    Soloviev, M. M., Ciruela, F., Lujan, R., Chan, W. Y. & McIlhinney, R. A. J. 1999 In : Journal of neurochemistry. 73, p. S138-S138 1 p.

    Research output: Contribution to journalSpecial issue

  427. Published

    Identification, cloning and analysis of expression of a new alternatively spliced form of the metabotropic glutamate receptor mGluR1 mRNA1

    Soloviev, M. M., Ciruela, F., Chan, W. Y. & McIlhinney, R. A. 1999 In : BBA - Gene Structure and Expression . 1446, 1-2, p. 161-6 6 p.

    Research output: Contribution to journalArticle

  428. Published

    Influence of DNA delivery method on gene targeting frequencies in human cells

    Yáñez, R. J. & Porter, A. C. G. 1999 In : Somat Cell Mol Genet. 25, 1, p. 27-31 5 p.

    Research output: Contribution to journalArticle

  429. Published

    Neurulation and neural tube closure defects

    Copp, A. J., Cogram, P., Fleming, A., Gerrelli, D., Henderson, D. J., Hynes, A., Kolatsi-Joannou, M., Murdoch, J. N., Ybot-Gonzalez, P., Tuan, R. S. & Lo, C. W. 1999 Developmental Biology Protocols, Volume 1. New York: Academic Press

    Research output: Chapter in Book/Report/Conference proceedingChapter

  430. Published

    Physical and transcriptional map of a three megabase region of mouse Chromosome 1 containing the gene for the neural tube defect mutant loop-tail ( Lp )

    Eddleston, J., Murdoch, J. N., Copp, A. J. & Stanier, P. 1999 In : Genomics. 56, 2, p. 149-159 11 p.

    Research output: Contribution to journalArticle

  431. Published

    Sequence and expression analysis of Nhlh1: a basic helix-loop-helix gene implicated in neurogenesis

    Murdoch, J. N., Eddleston, J., Leblond-Bourget, N., Stanier, P. & Copp, A. J. 1999 In : Developmental Genetics. 24, p. 165-177 13 p.

    Research output: Contribution to journalArticle

  432. 1998
  433. Published

    Gene therapy for hyperlipidaemia: Insights from heterologous muscle-based expression of serum apolipoprotein E (apoE) in apoE(-)/(-) mice

    Athanasopoulos, T., Drew, J., Dunckley, M. G., Goodman, J., Hassall, D. G., Riddell, D. R., Owen, J. S. & Dickson, G. Nov 1998 In : Atherosclerosis. 141, 1, p. 184-184 1 p.

    Research output: Contribution to journalArticle

  434. Published

    Efficient coexpression and secretion of antiatherogenic human apolipoprotein Al and lecithin-cholesterol acyltransferase by cultured muscle cells using adeno-associated virus plasmid vectors

    Fan, L., Drew, J., Dunckley, M. G., Owen, J. S. & Dickson, G. Oct 1998 In : Human Gene Therapy. 5, 10, p. 1434-1440 7 p.

    Research output: Contribution to journalArticle

  435. Published

    Characterization of human and rat brain myristoyl-CoA:protein N-myristoyltransferase: evidence for an alternative splice variant of the enzyme

    McIlhinney, R. A., Young, K., Egerton, M., Camble, R., White, A. & Soloviev, M. 1998 In : Biochemical journal. 333 ( Pt 3), p. 491-5 5 p.

    Research output: Contribution to journalArticle

  436. Published

    Effective restoration of dystrophin-associated proteins in vivo by adenovirus-mediated transfer of truncated dystrophin cDNAs

    Yuasa, K., Miyagoe, Y., Yamamoto, K., Nabeshima, Y., Dickson, G. & Takeda, S. 1998 In : FEBS Letters. 425, 2, p. 329-36 8 p.

    Research output: Contribution to journalArticle

  437. Published

    Efficient coexpression and secretion of anti-atherogenic human apolipoprotein AI and lecithin-cholesterol acyltransferase by cultured muscle cells using adeno-associated virus plasmid vectors

    Fan, L., Drew, J., Dunckley, M. G., Owen, J. S. & Dickson, G. 1998 In : Human Gene Therapy. 5, 10, p. 1434-40 7 p.

    Research output: Contribution to journalArticle

  438. Published

    Ekspressiia gena distrofina cheloveka v myshechnykh voloknakh mysheĭ mdx posle transfektsii s pomoshch'iu liposom i sinteticheskikh oligopeptidov

    Baranov, V. S., Tarasenko, O. V., Baranov, V. S., Tarasenko, O. V., Baranov, A. N., Kiselev, A. V., Ivashchenko, T. E., Evgrafov, O. V., Mikhailov, V. M. & Dickson, G. 1998 In : Genetika. 34, 7, p. 876-82 7 p.

    Research output: Contribution to journalArticle

  439. Published

    Human dystrophin gene expression in mdx muscles after in vivo ballistic tranfsection:application of synthetic oligopeptide complexes and ationic liposomes

    Baranov, V., Zelenin, A. & Dickson, G. 1998 NATO ASI Series, Gene Therapy. Xanthopolous, K. G. (ed.). Springer-Verlag, Vol. 105

    Research output: Chapter in Book/Report/Conference proceedingChapter

  440. Published

    Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors

    Anson, L. C., Chen, P. E., Wyllie, D. J., Colquhoun, D. & Schoepfer, R. 1998 In : The Journal of Neuroscience. 18, 2, p. 581-9 9 p.

    Research output: Contribution to journalArticle

  441. Published

    Insertion of two independent enhancers in the long terminal repeat of a self-inactivating vector results in high-titer retroviral vectors with tissue-specific expression

    Fassati, A., Bardoni, A., Sironi, M., Wells, D. J., Bresolin, N., Scarlato, G., Hatanaka, M., Yamaoka, S. & Dickson, G. 1998 In : Human Gene Therapy. 9, 17, p. 2459-68 10 p.

    Research output: Contribution to journalArticle

  442. Published

    Linkage mapping of Lims1 , the murine homolog of the human LIM domain gene PINCH , to mouse Chromosome 10

    Abu-Hayyeh, S., Eddleston, J., Murdoch, J. N., Tham, M., Copp, A. J. & Stanier, P. 1998 In : Cytogenetics and Cell Genetics. 82, p. 46-48 3 p.

    Research output: Contribution to journalArticle

  443. Published

    Lipofection of cultured mouse muscle cells: a direct comparison of Lipofectamine and DOSPER

    Dodds, E., Dunckley, M. G., Naujoks, K., Michaelis, U. & Dickson, G. 1998 In : Human Gene Therapy. 5, 4, p. 542-51 10 p.

    Research output: Contribution to journalArticle

  444. Published

    Mini- and full-length dystrophin gene transfer induces the recovery of nitric oxide synthase at the sarcolemma of mdx4cv skeletal muscle fibers

    Decrouy, A., Renaud, J. M., Lunde, J. A., Dickson, G. & Jasmin, B. J. 1998 In : Human Gene Therapy. 5, 1, p. 59-64 6 p.

    Research output: Contribution to journalArticle

  445. Published

    Modification of splicing in the dystrophin gene in cultured Mdx muscle cells by antisense oligoribonucleotides

    Dunckley, M. G., Manoharan, M., Villiet, P., Eperon, I. C. & Dickson, G. 1998 In : Human Molecular Genetics. 7, 7, p. 1083-90 8 p.

    Research output: Contribution to journalArticle

  446. Published

    Paralogous Sm22 à ( TAGLN ) genes map to mouse Chromosomes 1 and 9: further evidence for a paralogous relationship

    Stanier, P., Abu-Hayyeh, S., Eddleston, J., Murdoch, J. N. & Copp, A. J. 1998 In : Genomics. 51, p. 144-147 4 p.

    Research output: Contribution to journalArticle

  447. Published

    Plasticity of agonist binding sites in hetero-oligomers of the unitary glutamate receptor subunit XenU1

    Soloviev, M. M., Abutidze, K., Mellor, I., Streit, P., Grishin, E. V., Usherwood, P. N. & Barnard, E. A. 1998 In : Journal of neurochemistry. 71, 3, p. 991-1001 11 p.

    Research output: Contribution to journalArticle

  448. Published

    Therapeutic gene targeting

    Yáñez, R. J. & Porter, A. C. G. 1998 In : Gene Therapy. 5, p. 149-159 11 p.

    Research output: Contribution to journalArticle

  449. 1997
  450. Published

    Xenopus oocytes express a unitary glutamate receptor endogenously

    Soloviev, M. M. & Barnard, E. A. 17 Oct 1997 In : Journal of molecular biology. 273, 1, p. 14-18 5 p.

    Research output: Contribution to journalArticle

  451. Published

    Transgenic utrophin expression prevents DMD-like clinical signs in the dystrophin-utrophin deficient mouse.

    Rafael, J. A., Tinsley, J. M., Deconinck, A. E., Brown, S. C., Potter, A. C., Fisher, R., Trickett, J. I., Dickson, J. G. & Davies, K. E. Oct 1997 In : American Journal of Human Genetics. 61, 4, p. A358-A358 1 p.

    Research output: Contribution to journalArticle

  452. Published

    A dual-marker system for quantitative studies of myoblast transplantation in the mouse

    Beauchamp, J. R., Pagel, C. N. & Partridge, T. A. 27 Jun 1997 In : Cell transplantation. 63, 12, p. 1794-1797 4 p.

    Research output: Contribution to journalArticle

  453. Published

    A network of interacting transcriptional regulators involved in Drosophila neural fate specification revealed by the yeast two-hybrid system

    Alifragis, P., Poortinga, G., Parkhurst, S. M. & Delidakis, C. 1997 In : Proceedings of the National Academy of Sciences of the United States of America. 94, 24, p. 13099-104 6 p.

    Research output: Contribution to journalArticle

  454. Published

    African swine fever virus trans-prenyltransferase

    Alejo, A., Yáñez, R. J., Rodríguez, J. M., Viñuela, E. & Salas, M. L. 1997 In : Journal of Biological Chemistry. 272, 14, p. 9417-23 7 p.

    Research output: Contribution to journalArticle

  455. Published

    Bacterial beta-galactosidase and human dystrophin genes are expressed in mouse skeletal muscle fibers after ballistic transfection

    Zelenin, A. V., Kolesnikov, V. A., Tarasenko, O. A., Shafei, R. A., Zelenina, I. A., Mikhailov, V. V., Semenova, M. L., Kovalenko, D. V., Artemyeva, O. V., Ivaschenko, T. E., Evgrafov, O. V., Dickson, G. & Baranovand, V. S. 1997 In : FEBS Letters. 414, 2, p. 319-22 4 p.

    Research output: Contribution to journalArticle

  456. Published

    Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair

    Oliveros, M., Yáñez, R. J., Salas, M. L., Salas, J., Viñuela, E. & Blanco, L. 1997 In : Journal of Biological Chemistry. 272, 49, p. 30899-910 12 p.

    Research output: Contribution to journalArticle

  457. Published

    Duchenne muscular dystrophy

    Dickson, G. 1997 Strategies in Gene Therapy. Strauss, M. (ed.). DeGruyter, Berlin

    Research output: Chapter in Book/Report/Conference proceedingChapter

  458. Published

    Dystroglycan complex and its role in muscle development

    Brown, S. C. & Dickson, G. 1997 In : Basic Applied Myology. 6, p. 449-457 9 p.

    Research output: Contribution to journalArticle

  459. Published

    Gene therapy of Duchenne muscular dystrophy

    Turner, G., Dunckley, M. G. & Dickson, G. 1997 Dystrophin, Gene Protein and Cell Biology. Brown, S. C. & Lucy, J. A. (eds.). Cambridge University Press

    Research output: Chapter in Book/Report/Conference proceedingChapter

  460. Published

    Gene therapy of Duchenne muscular dystrophy

    Fassati, A., Murphy, S. & Dickson, G. 1997 In : Advances in Genetics. 35, p. 117-53 37 p.

    Research output: Contribution to journalArticle

  461. Published

    Genetic correction of dystrophin deficiency and skeletal muscle remodeling in adult MDX mouse via transplantation of retroviral producer cells

    Fassati, A., Wells, D. J., Sgro Serpente, P. A., Walsh, F. S., Brown, S. C., Strong, P. N. & Dickson, G. 1997 In : The Journal of clinical investigation. 100, 3, p. 620-8 9 p.

    Research output: Contribution to journalArticle

  462. Published

    Localisation of the mouse gene encoding tyrosine kinase receptor type 10 on distal Chromosome 1

    Murdoch, J. N., Eddleston, J., Stanier, P. & Copp, A. J. 1997 In : Mammalian Genome. 8, p. 941-952 12 p.

    Research output: Contribution to journalArticle

  463. Published

    Mini-dystrophin gene transfer in mdx4cv diaphragm muscle fibers increases sarcolemmal stability

    Decrouy, A., Renaud, J. M., Davis, H. L., Lunde, J. A., Dickson, G. & Jasmin, B. J. 1997 In : Human Gene Therapy. 4, 5, p. 401-8 8 p.

    Research output: Contribution to journalArticle

  464. Published

    Untitled

    Partridge, T., Beauchamp, J., Morgan, J., Tremblay, J. P., Huard, J., Watt, D., Wernig, A., Irintchev, A., Grounds, M., Springer, M. L., Bartlett, R. J., Mendell, J., Vilquin, J. T. & Bower, J. J. 1997 In : Cell transplantation. 6, 2, p. 195-196 2 p.

    Research output: Contribution to journalLetter

  465. Published

    Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy

    Deconinck, A. E., Rafael, J. A., Skinner, J. A., Brown, S. C., Potter, A. C., Metzinger, L., Watt, D. J., Dickson, J. G., Tinsley, J. M. & Davies, K. E. 1997 In : Cell. 90, 4, p. 717-727 11 p.

    Research output: Contribution to journalArticle

  466. 1996
  467. Published

    Functional expression of a recombinant unitary glutamate receptor from Xenopus, which contains N-methyl-D-aspartate (NMDA) and non-NMDA receptor subunits

    Soloviev, M. M., Brierley, M. J., Shao, Z. Y., Mellor, I. R., Volkova, T. M., Kamboj, R., Ishimaru, H., Sudan, H., Harris, J., Foldes, R. L., Grishin, E. V., Usherwood, P. N. R. & Barnard, E. A. 20 Dec 1996 In : Journal of Biological Chemistry. 271, 51, p. 32572-32579 8 p.

    Research output: Contribution to journalArticle

  468. Published

    Establishment of long-term myogenic cultures from patients with Duchenne muscular dystrophy by retroviral transduction of a temperature-sensitive SV40 large T antigen

    Simon, L. V., Beauchamp, J. R., OHare, M. & Olsen, I. 1 May 1996 In : Experimental cell research. 224, 2, p. 264-271 8 p.

    Research output: Contribution to journalArticle

  469. Published

    Gene therapy of Duchenne muscular dystrophy

    Dickson, G. 15 Apr 1996 In : Biophysical chemistry. 8, p. 294-297 4 p.

    Research output: Contribution to journalArticle

  470. Published

    A unitary non-NMDA receptor short subunit from Xenopus: DNA cloning and expression.

    Ishimaru, H., Kamboj, R., Ambrosini, A., Henley, J. M., Soloviev, M. M., Sudan, H., Rossier, J., Abutidze, K., Rampersad, V., Usherwood, P. N. R., Bateson, A. N. & Barnard, E. A. 1996 In : RECEPTORS. 4, 1, p. 31-49 19 p.

    Research output: Contribution to journalArticle

  471. Published

    Expression of full-length human dystrophin cDNA in mdx mouse muscle by HVJ-liposome injection

    Yanagihara, I., Inui, K., Dickson, G., Turner, G., Piper, T., Kaneda, Y. & Okada, S. 1996 In : Human Gene Therapy. 3, 6, p. 549-53 5 p.

    Research output: Contribution to journalArticle

  472. Published

    Gene therapy in Duchenne muscular dystrophy

    Inui, K., Okada, S. & Dickson, G. 1996 In : Brain & Development. 18, 5, p. 357-61 5 p.

    Research output: Contribution to journalArticle

  473. Published

    Modulation of pre-mRNA splicing in the Duchenne muscular dystrophy gene

    Dunckley, M. G., Eperon, I. C. & Dickson, G. 1996 In : Biochemical Society Transactions. 24, 2, p. 276S

    Research output: Contribution to journalArticle

  474. Published

    Novyĭ tip ionotropnykh glutamatnykh retseptorov

    Soloviev, M., Barnard, E. A. & Grishin, E. V. 1996 In : BIOORGANICHESKAYA KHIMIYA. 22, 6, p. 468-71 4 p.

    Research output: Contribution to journalArticle

  475. Published

    Transplantation of retroviral producer cells for in vivo gene transfer into mouse skeletal muscle

    Fassati, A., Wells, D. J., Walsh, F. S. & Dickson, G. 1996 In : Human Gene Therapy. 7, 5, p. 595-602 8 p.

    Research output: Contribution to journalArticle

  476. 1995
  477. Published

    FUNCTIONAL-CHARACTERIZATION OF GLUTAMATE RECEPTORS EXPRESSED FROM MOUSE AND FROG CDNAS

    SUDAN, H. L., SOLOVIEV, M., BARNARD, E. A. & USHERWOOD, P. N. R. Jul 1995 In : British Journal of Pharmacology. 115, p. P110-P110 1 p.

    Research output: Contribution to journalSpecial issue

  478. Published

    THE NITRATE AND NITRITE REDUCTASE-ENCODING GENES OF LEPTOSPHAERIA-MACULANS ARE CLOSELY LINKED AND TRANSCRIBED IN THE SAME DIRECTION

    WILLIAMS, R. S. B., DAVIS, M. A. & HOWLETT, B. J. 26 May 1995 In : Gene. 158, 1, p. 153-154 2 p.

    Research output: Contribution to journalComment/debate

  479. Published

    Analysis of the complete nucleotide sequence of African swine fever virus

    Yáñez, R. J., Rodríguez, J. M., Nogal, M. L., Yuste, L., Enríquez, C., Rodriguez, J. F. & Viñuela, E. 1995 In : Virology. 208, 1, p. 249-78 30 p.

    Research output: Contribution to journalArticle

  480. Published

    Cell and Molecular Biology of Human Gene Therapeutics

    Dickson, G. 1995 Chapman & Hall.

    Research output: Book/ReportBook

  481. Published

    Duchenne muscular dystrophy

    Dickson, G. & Brown, S. C. 1995 In : Molecular and cell biology of human diseases series. 5, p. 261-80 20 p.

    Research output: Contribution to journalArticle

  482. Published

    Dystrophin expression in the hair cells of the cochlea

    Dodson, H. C., Piper, T. A., Clarke, J. D., Quinlivan, R. M. & Dickson, G. 1995 In : Journal of neurocytology. 24, 8, p. 625-32 8 p.

    Research output: Contribution to journalArticle

  483. Published

    Efficiency of in vivo gene transfer using murine retroviral vectors is strain-dependent in mice

    Fassati, A., Wells, D. J., Walsh, F. S. & Dickson, G. 1995 In : Human Gene Therapy. 6, 9, p. 1177-83 7 p.

    Research output: Contribution to journalArticle

  484. Published

    Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy

    Wells, D. J., Wells, K. E., Asante, E. A., Turner, G., Sunada, Y., Campbell, K. P., Walsh, F. S. & Dickson, G. 1995 In : Human Molecular Genetics. 4, 8, p. 1245-50 6 p.

    Research output: Contribution to journalArticle

  485. Published

    Genetic basis of neural tube defects: the mouse gene loop-tail maps to a region of chromosome 1 syntenic with human 1q21-q23

    Stanier, P., Murdoch, J., Eddleston, J., Moore, G. E. & Copp, A. J. 1995 In : Genomics. 26, 3, p. 473-8 6 p.

    Research output: Contribution to journalArticle

  486. Published

    Liposome-mediated gene transfer into normal and dystrophin-deficient mouse myoblasts

    Trivedi, R. A. & Dickson, G. 1995 In : Journal of neurochemistry. 64, 5, p. 2230-8 9 p.

    Research output: Contribution to journalArticle

  487. Published

    Retroviral vectors

    Fassati, A., Dunckley, M. G. & Dickson, G. 1995 In : Molecular and cell biology of human diseases series. 5, p. 1-19 19 p.

    Research output: Contribution to journalArticle

  488. 1994
  489. Published

    NITRATE REDUCTASE OF THE ASCOMYCETOUS FUNGUS, LEPTOSPHAERIA-MACULANS - GENE SEQUENCE AND CHROMOSOMAL LOCATION

    WILLIAMS, R. S. B., DAVIS, M. A. & HOWLETT, B. J. 8 Jul 1994 In : Molecular microbiology. 244, 1, p. 18 8 p.

    Research output: Contribution to journalArticle

  490. Published

    MYOGENIC CELL-LINES DERIVED FROM TRANSGENIC MICE CARRYING A THERMOLABILE T-ANTIGEN - A MODEL SYSTEM FOR THE DERIVATION OF TISSUE-SPECIFIC AND MUTATION-SPECIFIC CELL-LINES

    MORGAN, J. E., BEAUCHAMP, J. R., PAGEL, C. N., PECKHAM, M., ATALIOTIS, P., JAT, P. S., NOBLE, M. D., FARMER, K. & PARTRIDGE, T. A. Apr 1994 In : Developmental Biology. 162, 2, p. 486-498 13 p.

    Research output: Contribution to journalArticle

  491. Published

    MYOGENIC CELLS WITH STEM-CELL PROPERTIES

    PARTRIDGE, T., MORGAN, J., PAGEL, C., BEAUCHAMP, J., PECKHAM, M., NOBLE, M. & JAT, P. 13 Feb 1994 In : Journal of cellular biochemistry. p. 266-266 1 p.

    Research output: Contribution to journalArticle

  492. Published

    Adenovirus-mediated gene transfer to murine retinal cells in vitro and in vivo

    Jomary, C., Piper, T. A., Dickson, G., Couture, L. A., Smith, A. E., Neal, M. J. & Jones, S. E. 1994 In : FEBS Letters. 347, 2-3, p. 117-22 6 p.

    Research output: Contribution to journalArticle

  493. Published

    African swine fever virus membrane-associated and secreted proteins

    Rodríguez, J. M., Almazán, F., Yáñez, R. J., García, R., Viñuela, E. & Rodriguez, J. F. 1994 Viroceptors, virokines and related immune modulators encoded by DNA viruses. McFadden, G. (ed.). Georgetown, Texas, USA: Landes Company, p. 187-200

    Research output: Chapter in Book/Report/Conference proceedingChapter

  494. Published

    Characterization and molecular basis of heterogeneity of the African swine fever virus envelope protein p54

    Rodríguez, F., Alcaraz, C., Eiras, A., Yáñez, R. J., Rodríguez, J. M., Alonso, C., Rodriguez, J. F. & Escribano, J. M. 1994 In : J Virol. 68, 11, p. 7244-52 9 p.

    Research output: Contribution to journalArticle

  495. Published

    Developmental basis of severe neural tube defects in the loop-tail (Lp) mutant mouse: use of microsatellite DNA markers to identify embryonic genotype

    Copp, A. J., Checiu, I. & Murdoch, J. 1994 In : Developmental Biology. 165, 1, p. 20-9 10 p.

    Research output: Contribution to journalArticle

  496. Published

    Independent localization of dystrophin N- and C-terminal regions to the sarcolemma of mdx mouse myofibres in vivo

    Dunckley, M. G., Wells, K. E., Piper, T. A., Wells, D. J. & Dickson, G. 1994 In : Journal of Cell Science. 107 ( Pt 6), p. 1469-75 7 p.

    Research output: Contribution to journalArticle

  497. Published

    Multigene families in African swine fever virus: family 505

    Rodríguez, J. M., Yáñez, R. J., Pan, R., Rodriguez, J. F., Salas, M. L. & Viñuela, E. 1994 In : J Virol. 68, 4, p. 2746-51 6 p.

    Research output: Contribution to journalArticle

  498. Published

    Production of high titre helper-free recombinant retroviral vectors by lipofection

    Fassati, A., Takahara, Y., Walsh, F. S. & Dickson, G. 1994 In : Nucleic Acids Research. 22, 6, p. 1117-8 2 p.

    Research output: Contribution to journalArticle

  499. 1993
  500. Published

    BEHAVIOR OF CONDITIONALLY IMMORTAL MYOGENIC CELLS-INVITRO AND INVIVO

    BEAUCHAMP, J. R., MORGAN, J. E., PAGEL, C. N. & PARTRIDGE, T. A. Apr 1993 In : Journal of muscle research and cell motility. 14, 2, p. 223-223 1 p.

    Research output: Contribution to journalArticle

  501. Published

    BEHAVIOR OF MYOGENIC CELLS INVIVO

    PAGEL, C. N., MORGAN, J. E., BEAUCHAMP, J. R. & PARTRIDGE, T. A. Apr 1993 In : Journal of muscle research and cell motility. 14, 2, p. 223-223 1 p.

    Research output: Contribution to journalArticle

  502. Published

    African swine fever virus encodes a CD2 homolog responsible for the adhesion of erythrocytes to infected cells

    Rodríguez, J. M., Yáñez, R. J., Almazán, F., Viñuela, E. & Rodriguez, J. F. 1993 In : J Virol. 67, 9, p. 5312-20 9 p.

    Research output: Contribution to journalArticle

  503. Published

    African swine fever virus encodes a DNA ligase

    Yáñez, R. J. & Viñuela, E. 1993 In : Virology. 193, 1, p. 531-6 6 p.

    Research output: Contribution to journalArticle

  504. Published

    African swine fever virus encodes two genes which share significant homology with the two largest subunits of DNA-dependent RNA polymerases

    Yáñez, R. J., Boursnell, M., Nogal, M. L., Yuste, L. & Viñuela, E. 1993 In : Nucleic Acids Research. 21, 10, p. 2423-7 5 p.

    Research output: Contribution to journalArticle

  505. Published

    African swine fever virus guanylyltransferase

    Pena, L., Yáñez, R. J., Revilla, Y., Viñuela, E. & Salas, M. L. 1993 In : Virology. 193, 1, p. 319-28 10 p.

    Research output: Contribution to journalArticle

  506. Published

    African swine fever virus thymidylate kinase gene: sequence and transcriptional mapping

    Yáñez, R. J., Rodríguez, J. M., Rodriguez, J. F., Salas, M. L. & Viñuela, E. 1993 In : J Gen Virol. 74 ( Pt 8), p. 1633-8 6 p.

    Research output: Contribution to journalArticle

  507. Published

    Direct retroviral-mediated transfer of a dystrophin minigene into mdx mouse muscle in vivo

    Dunckley, M. G., Wells, D. J., Walsh, F. S. & Dickson, G. 1993 In : Human Molecular Genetics. 2, 6, p. 717-23 7 p.

    Research output: Contribution to journalArticle

  508. Published

    Duchenne Muscular Dystrophy: from gene to gene therapy

    Dickson, G. 1993 In : Acta Card. 5, p. 159-165 7 p.

    Research output: Contribution to journalArticle

  509. Published

    Human dystrophin gene transfer: genetic correction of dystrophin deficiency

    Dickson, G. & Dunckley, M. 1993 In : Molecular and cell biology of human diseases series. 3, p. 283-302 20 p.

    Research output: Contribution to journalArticle

  510. Published

    Magnetic affinity cell sorting (MACS) separation and flow cytometric characterization of neural cell adhesion molecule-positive, cultured myogenic cells from normal and dystrophic dogs

    Prattis, S. M., Gebhart, D. H., Dickson, G., Watt, D. J. & Kornegay, J. N. 1993 In : Experimental cell research. 208, 2, p. 453-64 12 p.

    Research output: Contribution to journalArticle

  511. Published

    Retroviral-mediated gene transfer and Duchenne muscular dystrophy

    Dunckley, M. G. & Dickson, G. 1993 Gene Therapeutics. Wolff, J. A. (ed.). Birkhauser, Boston

    Research output: Chapter in Book/Report/Conference proceedingChapter

  512. Published

    The DNA polymerase-encoding gene of African swine fever virus: sequence and transcriptional analysis

    Rodríguez, J. M., Yáñez, R. J., Rodriguez, J. F., Viñuela, E. & Salas, M. L. 1993 In : Gene. 136, 1-2, p. 103-10 8 p.

    Research output: Contribution to journalArticle

  513. Published

    Trans-activation of the murine dystrophin gene in human-mouse hybrid myotubes

    Noursadeghi, M., Walsh, F. S., Heiman-Patterson, T. & Dickson, G. 1993 In : FEBS Letters. 320, 2, p. 155-9 5 p.

    Research output: Contribution to journalArticle

  514. Published

    Two putative African swine fever virus helicases similar to yeast 'DEAH' pre-mRNA processing proteins and vaccinia virus ATPases D11L and D6R

    Yáñez, R. J., Rodríguez, J. M., Boursnell, M., Rodriguez, J. F. & Viñuela, E. 1993 In : Gene. 134, 2, p. 161-74 14 p.

    Research output: Contribution to journalArticle

  515. 1992
  516. Published

    EXPRESSION AND FUNCTION OF HETEROTYPIC ADHESION MOLECULES DURING DIFFERENTIATION OF HUMAN SKELETAL-MUSCLE IN CULTURE

    BEAUCHAMP, J. R., ABRAHAM, D. J., BOUGHARIOS, G., PARTRIDGE, T. A. & OLSEN, I. Feb 1992 In : American Journal of Pathology. 140, 2, p. 387-401 15 p.

    Research output: Contribution to journalArticle

  517. Published

    Characterization of a 4.8kb transcript from the Duchenne muscular dystrophy locus expressed in Schwannoma cells

    Blake, D. J., Love, D. R., Tinsley, J., Morris, G. E., Turley, H., Gatter, K., Dickson, G., Edwards, Y. H. & Davies, K. E. 1992 In : Human Molecular Genetics. 1, 2, p. 103-9 7 p.

    Research output: Contribution to journalArticle

  518. Published

    Co-localization and molecular association of dystrophin with laminin at the surface of mouse and human myotubes

    Dickson, G., Azad, A., Morris, G. E., Simon, H., Noursadeghi, M. & Walsh, F. S. 1992 In : Journal of Cell Science. 103 ( Pt 4), p. 1223-33 11 p.

    Research output: Contribution to journalArticle

  519. Published

    Human dystrophin expression corrects the myopathic phenotype in transgenic mdx mice

    Wells, D. J., Wells, K. E., Walsh, F. S., Davies, K. E., Goldspink, G., Love, D. R., Chan-Thomas, P., Dunckley, M. G., Piper, T. & Dickson, G. 1992 In : Human Molecular Genetics. 1, 1, p. 35-40 6 p.

    Research output: Contribution to journalArticle

  520. Published

    Retroviral-mediated transfer of a dystrophin minigene into mdx mouse myoblasts in vitro

    Dunckley, M. G., Love, D. R., Davies, K. E., Walsh, F. S., Morris, G. E. & Dickson, G. 1992 In : FEBS Letters. 296, 2, p. 128-34 7 p.

    Research output: Contribution to journalArticle

  521. 1991
  522. Published

    LOCALIZATION OF THE DMDL GENE-ENCODED DYSTROPHIN-RELATED PROTEIN USING A PANEL OF 19 MONOCLONAL-ANTIBODIES - PRESENCE AT NEUROMUSCULAR-JUNCTIONS, IN THE SARCOLEMMA OF DYSTROPHIC SKELETAL-MUSCLE, IN VASCULAR AND OTHER SMOOTH MUSCLES, AND IN PROLIFERATING BRAIN-CELL LINES

    MAN, N. T., ELLIS, J. M., LOVE, D. R., DAVIES, K. E., GATTER, K. C., DICKSON, G. & MORRIS, G. E. Dec 1991 In : The Journal of cell biology. 115, 6, p. 1695-1700 6 p.

    Research output: Contribution to journalArticle

  523. Published

    FUNCTION AND REGULATION OF THE MURINE LYMPHOCYTE CD2 RECEPTOR

    ABRAHAM, D. J., BOUGHARIOS, G., BEAUCHAMP, J. R., PLATERZYBERK, C., MAINI, R. N. & OLSEN, I. Apr 1991 In : Journal of leukocyte biology. 49, 4, p. 329-341 13 p.

    Research output: Contribution to journalArticle

  524. Published

    Choline acetyltransferase messenger RNA expression in developing and adult rat brain: regulation by nerve growth factor

    Cavicchioli, L., Flanigan, T. P., Dickson, J. G., Vantini, G., Dal Toso, R., Fusco, M., Walsh, F. S. & Leon, A. 1991 In : Brain research. Molecular brain research. 9, 4, p. 319-25 7 p.

    Research output: Contribution to journalArticle

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