1. 2012
  2. Published

    Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector

    Hutson, T. H., Verhaagen, J., Yáñez-Muñoz, R. J. & Moon, L. D. F. Jan 2012 In : Gene Therapy. 19, 1, p. 49-60 12 p.

    Research output: Contribution to journalArticle

  3. Published

    AMP-Activated Protein Kinase (AMPK) - Dependent and -Independent Pathways Regulate Hypoxic Inhibition of Transepithelial Na(+) Transport Across Human Airway Epithelial Cells

    Tan, C. D., Smolenski, R. T., Harhun, M. I., Patel, H. K., Ahmed, S. G., Wanisch, K., Yáñez (or Yáñez-Muñoz) , R. J. & Baines, D. L. 2012 In : British Journal of Pharmacology.

    Research output: Contribution to journalArticle

  4. Published

    Amyloid-β Acts as a Regulator of Neurotransmitter Release Disrupting the Interaction between Synaptophysin and VAMP2

    Russell, C. L., Semerdjieva, S., Empson, R. M., Austen, B. M., Beesley, P. W. & Alifragis, P. 2012 In : PLoS One. 7, 8, p. e43201

    Research output: Contribution to journalArticle

  5. Published

    Assembly of protein building blocks using a short synthetic peptide

    Ferrari, E., Soloviev, M., Niranjan, D., Arsenault, J., Gu, C., Vallis, Y., O'Brien, J. & Davletov, B. 2012 In : Bioconjugate Chemistry. 23, 3, p. 479-84 6 p.

    Research output: Contribution to journalArticle

  6. Published

    Brainstem respiratory oscillators develop independently of neuronal migration defects in the Wnt/PCP mouse mutant looptail

    Thoby-Brisson, M., Bouvier, J., Glasco, D. M., Stewart, M. E., Dean, C., Murdoch, J. N., Champagnat, J., Fortin, G. & Chandrasekhar, A. 2012 In : PLoS One. 7, 2, p. e31140

    Research output: Contribution to journalArticle

  7. Published

    Challenges for gene therapy of CNS disorders and implications for Parkinson's disease therapies

    Broadstock, M. & Yáñez (or Yáñez-Muñoz) , R. J. 2012 In : Human Gene Therapy. 23, 4, p. 340-3 4 p.

    Research output: Contribution to journalComment/debate

  8. Published

    Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases

    Yáñez (or Yáñez-Muñoz) , R. J. , Dickson, G. , Popplewell, L. & 28 others Daboussi, F., Zaslavskiy, M., Poirot, L., Loperfido, M., Gouble, A., Guyot, V., Leduc, S., Galetto, R., Grizot, S., Oficjalska, D., Perez, C., Delacôte, F., Dupuy, A., Chion-Sotinel, I., Le Clerre, D., Lebuhotel, C., Danos, O., Lemaire, F., Oussedik, K., Cédrone, F., Epinat, J-C., Smith, J., Koo, T., Vandendriessche, T., Chuah, M. K., Duclert, A., Duchateau, P. & Pâques, F. 2012 In : Nucleic Acids Research.

    Research output: Contribution to journalArticle

  9. Published
  10. Published

    Effect of gold nanoparticle conjugation on the activity and stability of functional proteins

    Bailes, J., Gazi, S., Ivanova, R. & Soloviev, M. 2012 In : Methods in Molecular Biology. 906, p. 89-99 11 p.

    Research output: Contribution to journalArticle

  11. Published

    Evaluation of Bacillus subtilis strains as probiotics and their potential as a food ingredient

    Permpoonpattana, P., Hong, H. A., Khaneja, R. & Cutting, S. M. 2012 In : Beneficial microbes. 3, 2, p. 127-35 9 p.

    Research output: Contribution to journalArticle

  12. Published

    Genetic Therapeutic Approaches for Duchenne Muscular Dystrophy

    Foster, H., Popplewell, L. J. & Dickson, G. 2012 In : Human Gene Therapy.

    Research output: Contribution to journalScientific review

  13. Published

    Gold nanoparticle antibody conjugates for use in competitive lateral flow assays

    Bailes, J., Mayoss, S., Teale, P. & Soloviev, M. 2012 In : Methods in Molecular Biology. 906, p. 45-55 11 p.

    Research output: Contribution to journalArticle

  14. Published

    Killed Bacillus subtilis spores as a mucosal adjuvant for an H5N1 vaccine

    Song, M., Hong, H. A., Huang, J-M., Colenutt, C., Khang, D. D., Nguyen, T. V. A., Park, S-M., Shim, B-S., Song, H. H., Cheon, I. S., Jang, J. E., Choi, J., Choi, Y. K., Stadler, K. & Cutting, S. M. 2012 In : Vaccine. 30, 22, p. 3266-77 12 p.

    Research output: Contribution to journalArticle

  15. Published

    Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones

    Hutson, T. H., Foster, E., Dawes, J. M., Hindges, R., Yáñez (or Yáñez-Muñoz) , R. J. & Moon, L. D. F. 2012 In : Journal of Gene Medicine. 14, 5, p. 299-315 17 p.

    Research output: Contribution to journalArticle

  16. Published

    Novel cationic carotenoid lipids as delivery vectors of antisense oligonucleotides for exon skipping in duchenne muscular dystrophy

    Popplewell, L. J., Abu-Dayya, A., Khana, T., Flinterman, M., Khalique, N. A., Raju, L., Opstad, C. L., Sliwka, H-R., Partali, V., Dickson, G. & Pungente, M. D. 2012 In : Molecules. 17, 2, p. 1138-48 11 p.

    Research output: Contribution to journalArticle

  17. Published

    Optimizing antisense oligonucleotides using phosphorodiamidate morpholino oligomers

    Popplewell, L. J., Malerba, A. & Dickson, G. 2012 In : Methods in Molecular Biology. 867, p. 143-67 25 p.

    Research output: Contribution to journalArticle

  18. Published

    Poly(A) binding protein nuclear 1 levels affect alternative polyadenylation

    de Klerk, E., Venema, A., Anvar, S. Y., Goeman, J. J., Hu, O., Trollet, C., Dickson, G., den Dunnen, J. T., van der Maarel, S. M., Raz, V. & 't Hoen, P. A. C. 2012 In : Nucleic Acids Research.

    Research output: Contribution to journalArticle

  19. Published

    Spores, sporulation and germination

    Prajapati, R. S. & Cutting, S. 2012 Molecular Medical Microbiology. Academic Press, p. 199 208 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  20. Published

    The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium

    Chang, P., Orabi, B., Deranieh, R. M., Dham, M., Hoeller, O., Shimshoni, J. A., Yagen, B., Bialer, M., Greenberg, M. L., Walker, M. C. & Williams, R. S. B. 2012 In : Disease Models and Mechanisms. 5, p. 115-124

    Research output: Contribution to journalArticle

  21. Published
  22. Published

    The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium

    Stowe, T. R., Wilkinson, C. J., Iqbal, A. & Stearns, T. 2012 In : Molecular biology of the cell. 23, 17, p. 3322-35 14 p.

    Research output: Contribution to journalArticle

  23. Published

    The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled

    Glasco, D. M., Sittaramane, V., Bryant, W., Fritzsch, B., Sawant, A., Paudyal, A., Stewart, M., Andre, P., Cadete Vilhais-Neto, G., Yang, Y., Song, M-R., Murdoch, J. N. & Chandrasekhar, A. 2012 In : Developmental Biology. 369, 2, p. 211-22 12 p.

    Research output: Contribution to journalArticle

  24. Published

    The Use of EST Expression Matrixes for the Quality Control of Gene Expression Data

    Milnthorpe, A. T. & Soloviev, M. 2012 In : PLoS One. 7, 3, p. e32966

    Research output: Contribution to journalArticle

  25. Published

    Zizimin and Dock guanine nucleotide exchange factors in cell function and disease

    Pakes, N. K., Veltman, D. M. & Williams, R. 2012 In : Small GTPases. 4, 1

    Research output: Contribution to journalArticle

  26. 2011
  27. Published

    Surface layers of Clostridium difficile endospores

    Permpoonpattana, P., Tolls, E. H., Nadem, R., Tan, S., Brisson, A. & Cutting, S. M. Dec 2011 In : Journal of Bacteriology. 193, 23, p. 6461-6470 10 p.

    Research output: Contribution to journalArticle

  28. Published

    Investigating the Effect of Emetic Compounds on Chemotaxis in Dictyostelium Identifies a Non-Sentient Model for Bitter and Hot Tastant Research

    Robery, S., Mukanowa, J., Percie du Sert, N., Andrews, P. L. R. & Williams, R. S. B. 8 Sep 2011 In : PLoS One. 6, 9, p. e24439

    Research output: Contribution to journalArticle

  29. Published

    Long-term functional adeno-associated virus-microdystrophin expression in the dystrophic CXMDj dog

    Koo, T., Okada, T., Athanasopoulos, T., Foster, H., Takeda, S. & Dickson, G. Sep 2011 In : Journal of Gene Medicine. 13, 9, p. 497-506 10 p.

    Research output: Contribution to journalArticle

  30. Published

    Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

    Cirak, S., Arechavala-Gomeza, V., Guglieri, M., Feng, L., Torelli, S., Anthony, K., Abbs, S., Garralda, M. E., Bourke, J., Wells, D. J., Dickson, G., Wood, M. J. A., Wilton, S. D., Straub, V., Kole, R., Shrewsbury, S. B., Sewry, C., Morgan, J. E., Bushby, K. & Muntoni, F. 13 Aug 2011 In : The Lancet. 378, 9791, p. 595-605 11 p.

    Research output: Contribution to journalArticle

  31. Published

    Bio-electrospraying and aerodynamically assisted bio-jetting the model eukaryotic Dictyostelium discoideum: assessing stress and developmental competency post treatment

    Pakes, N. K., Jayasinghe, S. N. & Williams, R. S. B. 7 Aug 2011 In : Journal of the Royal Society. Interface. 8, 61, p. 1185-1191 7 p.

    Research output: Contribution to journalArticle

  32. Published

    Getting to the Heart of Things in the Field of Cardiovascular Gene Therapy

    Dickson, G. Aug 2011 In : Human Gene Therapy. 22, 8, p. 911-912 2 p.

    Research output: Contribution to journalEditorial

  33. Published
  34. Published

    Identifying an uptake mechanism for the antiepileptic and bipolar disorder treatment valproic acid using the simple biomedical model Dictyostelium

    Terbach, N., Shah, R., Kelemen, R., Klein, P. S., Gordienko, D., Brown, N. A., Wilkinson, C. J. & Williams, R. S. B. 1 Jul 2011 In : Journal of Cell Science. 124, Pt 13, p. 2267-2276 10 p.

    Research output: Contribution to journalArticle

  35. Published

    Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B

    Permpoonpattana, P., Hong, H. A., Phetcharaburanin, J., Huang, J-M., Cook, J., Fairweather, N. F. & Cutting, S. M. Jun 2011 In : Infection and Immunity. 79, 6, p. 2295-2302 8 p.

    Research output: Contribution to journalArticle

  36. Published

    Identification and the developmental formation of carotenoid pigments in the yellow/orange Bacillus spore-formers

    Perez-Fons, L., Steiger, S., Khaneja, R., Bramley, P. M., Cutting, S. M., Sandmann, G. & Fraser, P. D. Mar 2011 In : Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids . 1811, 3, p. 177-185 9 p.

    Research output: Contribution to journalArticle

  37. Published

    Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice

    Malerba, A., Sharp, P. S., Graham, I. R., Arechavala-Gomeza, V., Foster, K., Muntoni, F., Wells, D. J. & Dickson, G. Feb 2011 In : Molecular Therapy. 19, 2, p. 345-354

    Research output: Contribution to journalArticle

  38. Published

    Molecular pharmacology in a simple model system: Implicating MAP kinase and phosphoinositide signalling in bipolar disorder

    Ludtmann, M. H. R., Boeckeler, K. & Williams, R. S. B. Feb 2011 In : Seminars in Cell and Developmental Biology. 22, 1, p. 105-113 9 p.

    Research output: Contribution to journalScientific review

  39. Published
  40. Published

    Adeno-associated virus serotypes 7 and 8 outperform serotype 9 in expressing atheroprotective human apoE3 from mouse skeletal muscle

    Evans, V. C., Graham, I. R., Athanasopoulos, T., Galley, D. J., Jackson, C. L., Simons, J. P., Dickson, G. & Owen, J. S. 2011 In : Metabolism: clinical and experimental. 60, 4, p. 491-8

    Research output: Contribution to journalArticle

  41. Published
  42. Published

    Bacillus probiotics

    Cutting, S. M. 2011 In : Food Microbiology. 28, 2, p. 214-20 7 p.

    Research output: Contribution to journalArticle

  43. Published

    Bioinformatic and Functional Optimization of Antisense Phosphorodiamidate Morpholino Oligomers (PMOs) for Therapeutic Modulation of RNA Splicing in Muscle

    Popplewell, L. J., Graham, I. R., Malerba, A. & Dickson, G. 2011 In : Methods in Molecular Biology. 709, p. 153-78 26 p.

    Research output: Contribution to journalArticle

  44. Published

    Carbohydrate-active enzymes from pigmented Bacilli: a genomic approach to assess carbohydrate utilization and degradation

    Manzo, N., D'Apuzzo, E., Coutinho, P. M., Cutting, S. M., Henrissat, B. & Ricca, E. 2011 In : BMC Microbiology. 11, p. 198

    Research output: Contribution to journalArticle

  45. Published

    Chromosome rearrangement associated inactivation of tumour suppressor genes in prostate cancer

    Mao, X., Boyd, L. K., Yáñez-Muñoz, R. J., Chaplin, T., Xue, L., Lin, D., Shan, L., Berney, D. M., Young, B. D. & Lu, Y. J. 2011 In : American Journal of Cancer Research. 1, p. 604-617

    Research output: Contribution to journalArticle

  46. Published

    Codon optimization of the microdystrophin gene for duchene muscular dystrophy gene therapy

    Athanasopoulos, T., Foster, H., Foster, K. & Dickson, G. 2011 In : Methods in Molecular Biology. 709, p. 21-37 17 p.

    Research output: Contribution to journalArticle

  47. Published

    Current Status of Pharmaceutical and Genetic Therapeutic Approaches to Treat DMD

    Pichavant, C., Aartsma-Rus, A., Clemens, P. R., Davies, K. E., Dickson, G., Takeda, S., Wilton, S. D., Wolff, J. A., Wooddell, C. I., Xiao, X. & Tremblay, J. P. 2011 In : Molecular Therapy. 19, 5, p. 830-40 11 p.

    Research output: Contribution to journalScientific review

  48. Published
  49. Published

    Deregulation of the ubiquitin-proteasome system is the predominant molecular pathology in OPMD animal models and patients

    Anvar, S. Y., 't Hoen, P. A., Venema, A., van der Sluijs, B., van Engelen, B., Snoeck, M., Vissing, J., Trollet, C., Dickson, G., Chartier, A., Simonelig, M., van Ommen, G-J. B., van der Maarel, S. M. & Raz, V. 2011 In : Skeletal Muscle. 1, 1, p. 15

    Research output: Contribution to journalArticle

  50. Published

    Errors in CGAP xProfiler and cDNA DGED: the importance of library parsing and gene selection algorithms

    Milnthorpe, A. T. & Soloviev, M. 2011 In : BMC Bioinformatics. 12, p. 97

    Research output: Contribution to journalArticle

  51. Published

    Lentiviral vector integration profiles differ in rodent postmitotic tissues

    Bartholomae, C. C., Arens, A., Balaggan, K. S., Yáñez-Muñoz, R. J., Montini, E., Howe, S. J., Paruzynski, A., Korn, B., Appelt, U., MacNeil, A., Cesana, D., Abel, U., Glimm, H., Naldini, L., Ali, R. R., Thrasher, A. J., von Kalle, C. & Schmidt, M. 2011 In : Molecular Therapy. 19, 4, p. 703-710

    Research output: Contribution to journalArticle

  52. Published

    Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons

    Zhao, R-R., Muir, E. M., Alves, J. N., Rickman, H., Allan, A. Y., Kwok, J. C., Roet, K. C. D., Verhaagen, J., Schneider, B. L., Bensadoun, J-C., Ahmed, S. G., Yáñez (or Yáñez-Muñoz) , R. J., Keynes, R. J., Fawcett, J. W. & Rogers, J. H. 2011 In : Journal of Neuroscience Methods. 201, 1, p. 228-38 11 p.

    Research output: Contribution to journalArticle

  53. Published

    Lobe-specific functions of Ca2+·calmodulin in alphaCa2+·calmodulin-dependent protein kinase II activation

    Jama, A. M., Gabriel, J., Al-Nagar, A. J., Martin, S., Baig, S. Z., Soleymani, H., Chowdhury, Z., Beesley, P. & Török, K. 2011 In : Journal of Biological Chemistry. 286, 14, p. 12308-16 9 p.

    Research output: Contribution to journalArticle

  54. Published

    RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense

    Riyahi, T. Y., Frese, F., Steinert, M., Omosigho, N. N., Glöckner, G., Eichinger, L., Orabi, B., Williams, R. S. B. & Noegel, A. A. 2011 In : PLoS One. 6, 11, p. e27311

    Research output: Contribution to journalArticle

  55. Published

    Transcription Factor Rational Design Improves Directed Differentiation of Human Mesenchymal Stem Cells Into Skeletal Myocytes

    Gonçalves, M. A., Janssen, J. M., Nguyen, Q. G., Athanasopoulos, T., Hauschka, S. D., Dickson, G. & de Vries, A. A. 2011 In : Molecular Therapy. 19, 7, p. 1331-41

    Research output: Contribution to journalArticle

  56. 2010
  57. Published

    NanoLock polypeptide for the permanent immobilization of recombinant proteins on SNAP25 functionalized supports

    Ferrari, E., Darios, F., Soloviev, M. & Davletov, B. 1 Nov 2010 In : European Cells and Materials. 20, SUPPL.3, p. 80 1 p.

    Research output: Contribution to journalArticle

  58. Published

    Canine microdystrophin results in remarkable expression and improvement in muscle pathology in a canine model of Duchenne Muscular Dystrophy following AAV gene transfer

    Koo, T., Shin, J. H., Athanasopoulos, T., Takashi, O., Foster, H., Shin'ichi, T. & Dickson, G. Oct 2010 In : Human Gene Therapy. 21, 10, p. 1469-1470 2 p.

    Research output: Contribution to journalArticle

  59. Published

    Evaluation of the truncated products of exon and multiple exon skipping in DMD therapy

    Foster, K., Jarmin, S., Beley, C., Foster, H., Garcia, L. & Dickson, G. Oct 2010 In : Neuromuscular Disorders. 20, 9-10, p. 642 1 p.

    Research output: Contribution to journalArticle

  60. Published

    Serum Proteomics in the Diagnosis and Treatment of Haematological Malignancies

    Smieszek, S., Bailes, J. & Soloviev, M. Oct 2010 In : Current Proteomics . 7, 3, p. 195-208 14 p.

    Research output: Contribution to journalScientific review

  61. Published

    Inhibition of long-term potentiation by valproic acid through modulation of cyclic AMP

    Chang, P., Chandler, K. E., Williams, R. S. B. & Walker, M. C. Aug 2010 In : Epilepsia. 51, 8, p. 1533-1542 10 p.

    Research output: Contribution to journalArticle

  62. Published

    Epidermal wound repair is regulated by the planar cell polarity signaling pathway

    Caddy, J., Wilanowski, T., Darido, C., Dworkin, S., Ting, S. B., Zhao, Q., Rank, G., Auden, A., Srivastava, S., Papenfuss, T. A., Murdoch, J. N., Humbert, P. O., Boulos, N., Weber, T., Zuo, J., Cunningham, J. M. & Jane, S. M. 20 Jul 2010 In : Developmental Cell. 19, 1, p. 138-147 10 p.

    Research output: Contribution to journalArticle

  63. Published

    Genetic Control of Lithium Sensitivity and Regulation of Inositol Biosynthetic Genes

    King, J., Keim, M., Teo, R., Weening, K. E., Kapur, M., McQuillan, K., Ryves, J., Rogers, B., Dalton, E., Williams, R. S. B. & Harwood, A. J. 17 Jun 2010 In : PLoS One. 5, 6, 10 p.

    Research output: Contribution to journalArticle

  64. Published

    Molecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres

    Trollet, C., Anvar, S. Y., Venema, A., Hargreaves, I. P., Foster, K., Vignaud, A., Ferry, A., Negroni, E., Hourde, C., Baraibar, M. A., 't Hoen, P. A. C., Davies, J. E., Rubinsztein, D. C., Heales, S. J., Mouly, V., van der Maarel, S. M., Butler-Browne, G., Raz, V. & Dickson, G. 1 Jun 2010 In : Human Molecular Genetics. 19, 11, p. 2191-2207 17 p.

    Research output: Contribution to journalArticle

  65. Published

    Carotenoids found in Bacillus

    Khaneja, R., Perez-Fons, L., Fakhry, S., Baccigalupi, L., Steiger, S., To, E., Sandmann, G., Dong, T. C., Ricca, E., Fraser, P. D. & Cutting, S. M. Jun 2010 In : Journal of applied microbiology. 108, 6, p. 1889-1902 14 p.

    Research output: Contribution to journalArticle

  66. Published

    A justice system that denies free will is not based on justice

    McEvoy, J. P. 18 May 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 20, p. E81-E81 1 p.

    Research output: Contribution to journalLetter

  67. Published

    Antisense Oligonucleotide-Induced Multiexon Skipping in Duchenne Muscular Dystrophy

    Popplewell, L. J. & Dickson, G. Apr 2010 In : Human Gene Therapy. 21, 4, p. 507-508 2 p.

    Research output: Contribution to journalMeeting abstract

  68. Published

    Reduced expression of the Ca2+transporter protein PMCA2 slows Ca2+dynamics in mouse cerebellar Purkinje neurones and alters the precision of motor coordination

    Empson, R. M., Turner, P. R., Nagaraja, R. Y., Beesley, P. W. & Knopfel, T. 15 Mar 2010 In : Journal of Physiology . 588, 6, p. 907-922 16 p.

    Research output: Contribution to journalArticle

  69. Published

    Affinity peptidomics: Peptide selection and affinity capture on hydrogels and microarrays

    Zhang, F., Dulneva, A., Bailes, J. & Soloviev, M. 2010 In : Methods in Molecular Biology. 615, p. 313-44 32 p.

    Research output: Contribution to journalArticle

  70. Published

    Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice

    Qu, Y., Glasco, D. M., Zhou, L., Sawant, A., Ravni, A., Fritzsch, B., Damrau, C., Murdoch, J. N., Evans, S., Pfaff, S. L., Formstone, C., Goffinet, A. M., Chandrasekhar, A. & Tissir, F. 2010 In : The Journal of Neuroscience. 30, 28, p. 9392-401 10 p.

    Research output: Contribution to journalArticle

  71. Published

    Bacillus probiotics

    Cutting, S. 2010 In : Food Microbiology.

    Research output: Contribution to journalArticle

  72. Published

    Bacterial-type oxygen detoxification and iron-sulfur cluster assembly in amoebal relict mitochondria

    Maralikova, B., Ali, V., Nakada-Tsukui, K., Nozaki, T., van der Giezen, M., Henze, K. & Tovar, J. 2010 In : Cellular Microbiology. 12, 3, p. 331-42 12 p.

    Research output: Contribution to journalArticle

  73. Published

    Basal enrichment within neuroepithelia suggests novel function(s) for Celsr1 protein

    Formstone, C. J., Moxon, C., Murdoch, J., Little, P. & Mason, I. 2010 In : Molecular and Cellular Neuroscience. 44, 3, p. 210-22 13 p.

    Research output: Contribution to journalArticle

  74. Published

    Binary polypeptide system for permanent and oriented protein immobilization

    Ferrari, E., Darios, F., Zhang, F., Niranjan, D., Bailes, J., Soloviev, M. & Davletov, B. 2010 In : Journal of Nanobiotechnology. 8, p. 9

    Research output: Contribution to journalArticle

  75. Published

    Challenges with advanced therapy medicinal products and how to meet them

    Dickson, J. G. & 66 others Schneider, C. K., Salmikangas, P., Jilma, B., Flamion, B., Todorova, L. R., Paphitou, A., Haunerova, I., Maimets, T., Trouvin, J-H., Flory, E., Tsiftsoglou, A., Sarkadi, B., Gudmundsson, K., O'Donovan, M., Migliaccio, G., Ancāns, J., Maciulaitis, R., Robert, J-L., Samuel, A., Ovelgönne, J. H., Hystad, M., Fal, A. M., Lima, B. S., Moraru, A. S., Turcáni, P., Zorec, R., Ruiz, S., Akerblom, L., Narayanan, G., Kent, A., Bignami, F., Niederwieser, D., Figuerola-Santos, M-A., Reischl, I. G., Beuneu, C., Georgiev, R., Vassiliou, M., Pychova, A., Clausen, M., Methuen, T., Lucas, S., Schüssler-Lenz, M., Kokkas, V., Buzás, Z., MacAleenan, N., Galli, M. C., Linē, A., Gulbinovic, J., Berchem, G., Fraczek, M., Menezes-Ferreira, M., Vilceanu, N., Hrubisko, M., Marinko, P., Timón, M., Cheng, W., Crosbie, G. A., Meade, N., di Paola, M. L., VandenDriessche, T., Ljungman, P., D'Apote, L., Oliver-Diaz, O., Büttel, I., Celis, P. & Committee for Advanced Therapies (CAT) 2010 In : Nature Reviews. Drug Discovery. 9, 3, p. 195-201 7 p.

    Research output: Contribution to journalArticle

  76. Published

    Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials

    Popplewell, L. J., Adkin, C., Arechavala-Gomeza, V., Aartsma-Rus, A., de Winter, C. L., Wilton, S. D., Morgan, J. E., Muntoni, F., Graham, I. R. & Dickson, G. 2010 In : Neuromuscular disorders. 20, 2, p. 102-10 9 p.

    Research output: Contribution to journalArticle

  77. Published

    Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat

    Yip, P. K., Wong, L. F., Sears, T. A., Yáñez-Muñoz, R. J. & McMahon, S. B. 2010 In : PLoS Biology. 8, 6, e1000399

    Research output: Contribution to journalArticle

  78. Published

    Labelling of live cells using fluorescent aptamers: binding reversal with DNA nucleases

    Terazono, H., Anzai, Y., Soloviev, M. & Yasuda, K. 2010 In : Journal of Nanobiotechnology. 8, p. 8

    Research output: Contribution to journalArticle

  79. Published

    Mucosal delivery of antigens using adsorption to bacterial spores

    Huang, J-M., Hong, H. A., Van Tong, H., Hoang, T. H., Brisson, A. & Cutting, S. M. 2010 In : Vaccine. 28, 4, p. 1021-30 10 p.

    Research output: Contribution to journalArticle

  80. Published

    Oral delivery of a DNA vaccine against tuberculosis using operator-repressor titration in a Salmonella enterica vector

    Huang, J-M., Sali, M., Leckenby, M. W., Radford, D. S., Huynh, H. A., Delogu, G., Cranenburgh, R. M. & Cutting, S. M. 2010 In : Vaccine. 28, 47, p. 7523-8 6 p.

    Research output: Contribution to journalArticle

  81. Published

    Peptidomics: divide et impera

    Soloviev, M. 2010 In : Methods in Molecular Biology. 615, p. 3-9 7 p.

    Research output: Contribution to journalArticle

  82. Published

    Production of non viral DNA vectors

    Schleef, M., Blaesen, M., Schmeer, M., Baier, R., Marie, C., Dickson, G. & Scherman, D. 2010 In : Current Gene Therapy. 10, 6, p. 487-507 21 p.

    Research output: Contribution to journalArticle

  83. Published

    Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary cilia

    Sugiyama, Y., Stump, R. J. W., Nguyen, A., Wen, L., Chen, Y., Wang, Y., Murdoch, J. N., Lovicu, F. J. & McAvoy, J. W. 2010 In : Developmental Biology. 338, 2, p. 193-201 9 p.

    Research output: Contribution to journalArticle

  84. Published

    SNARE tagging allows stepwise assembly of a multimodular medicinal toxin

    Darios, F., Niranjan, D., Ferrari, E., Zhang, F., Soloviev, M., Rummel, A., Bigalke, H., Suckling, J., Ushkaryov, Y., Naumenko, N., Shakirzyanova, A., Giniatullin, R., Maywood, E., Hastings, M., Binz, T. & Davletov, B. 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 42, p. 18197-201 5 p.

    Research output: Contribution to journalArticle

  85. Published

    The Bone Morphogenetic Protein and Growth Differentiation Cytokine Family, and their Protein Antagonists

    Rider, C. C. & Mulloy, B. 2010 In : Biochemical Journal. 429, p. 1-12 12 p.

    Research output: Contribution to journalScientific review

  86. Published

    The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain

    Goncalves, M. B., Williams, E. J., Yip, P., Yáñez-Muñoz, R. J., Williams, G. & Doherty, P. 2010 In : British Journal of Pharmacology. 159, 5, p. 1118-25 8 p.

    Research output: Contribution to journalArticle

  87. Published

    The identification of chromosomal translocation, t(4;6)(q22;q15), in prostate cancer

    Yáñez-Muñoz, R. J. & 23 others Shan, L., Ambroisine, L., Clark, J., Fisher, G., Kudahetti, S. C., Yang, J., Kia, S., Mao, X., Fletcher, A., Flohr, P., Edwards, S., Attard, G., De-Bono, J., Young, B. D., Foster, C. S., Reuter, V., Moller, H., Oliver, T. D., Berney, D. M., Scardino, P., Cuzick, J., Cooper, C. S. & Lu, Y. J. 2010 In : Prostate Cancer and Prostatic Diseases. 13, 2, p. 117-25 9 p.

    Research output: Contribution to journalArticle

  88. Published

    The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

    Paudyal, A., Damrau, C., Patterson, V. L., Ermakov, A., Formstone, C., Lalanne, Z., Wells, S., Lu, X., Norris, D. P., Dean, C. H., Henderson, D. J. & Murdoch, J. N. 2010 In : BMC Developmental Biology. 10, p. 87

    Research output: Contribution to journalArticle

  89. Published

    The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

    Yates, L. L., Schnatwinkel, C., Murdoch, J. N., Bogani, D., Formstone, C. J., Townsend, S., Greenfield, A., Niswander, L. A. & Dean, C. H. 2010 In : Human Molecular Genetics. 19, 11, p. 2251-2267 17 p.

    Research output: Contribution to journalArticle

  90. Published

    The relationship between Sonic hedgehog signalling, cilia and neural tube defects.

    Murdoch, J. N. & Copp, A. J. 2010 In : Birth Defects Research Part A: Clinical and Molecular Teratology. 88, p. 633-652

    Research output: Contribution to journalArticle

  91. Published

    Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization

    Ghahramani Seno, M. M., Trollet, C., Athanasopoulos, T., Graham, I. R., Hu, P. & Dickson, G. 2010 In : BMC Genomics. 11, p. 345

    Research output: Contribution to journalArticle

  92. Published

    Using single cell cultivation system for on-chip monitoring of the interdivision timer in Chlamydomonas reinhardtii cell cycle

    Matsumura, K., Yagi, T., Hattori, A., Soloviev, M. & Yasuda, K. 2010 In : Journal of Nanobiotechnology. 8, p. 23

    Research output: Contribution to journalArticle

  93. 2009
  94. Published

    Development of thermo-stable Ad-based vaccines expressing ubiquitin fusions of full or fragmented HIV/SIV genetic components

    Athanasopoulos, T., Papagatsias, T., Meiser, A., Harris, J., Bachy, V., Benlahrech, A., Herath, S., Roesen, N., Oh, S., Li, F., Self, S., Kwon, S-Y., Fischer, K., Seymour, L., Daniels, R., Almond, N., Klavinskis, L., Logan, K., Patterson, S. & Dickson, G. Nov 2009 In : Human Gene Therapy. 20, 11, p. 1392-1393 2 p.

    Research output: Contribution to journalArticle

  95. Published

    Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

    Popplewell, L. , Dickson, G. & 23 others Kinali, M., Arechavala-Gomeza, V., Feng, L., Cirak, S., Hunt, D., Adkin, C., Guglieri, M., Ashton, E., Abbs, S., Nihoyannopoulos, P., Garralda, M. E., Rutherford, M., McCulley, C., Graham, I. R., Wood, M. J. A., Wells, D. J., Wilton, S. D., Kole, R., Straub, V., Bushby, K., Sewry, C., Morgan, J. E. & Muntoni, F. Oct 2009 In : Lancet Neurology. 8, 10, p. 918-928 11 p.

    Research output: Contribution to journalArticle

  96. Published

    PtdIns(3,4,5)P-3 and inositol depletion as a cellular target of mood stabilizers

    Teo, R., King, J., Dalton, E., Ryves, J., Williams, R. S. B. & Harwood, A. J. Oct 2009 In : Biochemical Society Transactions. 37, p. 1110-1114 5 p.

    Research output: Contribution to journalArticle

  97. Published

    Structure-function studies for the panacea, valproic acid

    Terbach, N. & Williams, R. S. B. Oct 2009 In : Biochemical Society Transactions. 37, p. 1126-1132 7 p.

    Research output: Contribution to journalArticle

  98. Published

    MOLECULAR INTERACTIONS OF THE PLASMA MEMBRANE CALCIUM ATPase 2 AT PRE- AND POST-SYNAPTIC SITES IN RAT CEREBELLUM

    Garside, M. L., Turner, P. R., Austen, B., Strehler, E. E., Beesley, P. W. & Empson, R. M. 18 Aug 2009 In : Neuroscience. 162, 2, p. 383-395 13 p.

    Research output: Contribution to journalArticle

  99. Published

    Gene therapy for muscular dystrophy: current progress and future prospects

    Trollet, C., Athanasopoulos, T., Popplewell, L., Malerba, A. & Dickson, G. Jul 2009 In : Expert Opinion on Biological Therapy. 9, 7, p. 849-866 18 p.

    Research output: Contribution to journalScientific review

  100. Published

    Pharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytes

    Puddifoot, C. A., Chen, P. E., Schoepfer, R. & Wyllie, D. J. A. Feb 2009 In : British Journal of Pharmacology. 156, 3, p. 509-518 10 p.

    Research output: Contribution to journalArticle

  101. Published

    Oral vaccine delivery by recombinant spore probiotics

    Cutting, S. M., Hong, H. A., Baccigalupi, L. & Ricca, E. 1 Jan 2009 In : International Reviews of Immunology. 28, 6, p. 487-505 19 p.

    Research output: Contribution to journalArticle

  102. Published

    Adeno-associated virus-8-mediated intravenous transfer of myostatin propeptide leads to systemic functional improvements of slow but not fast muscle

    Foster, K., Graham, I. R., Otto, A., Foster, H., Trollet, C., Yaworsky, P. J., Walsh, F. S., Bickham, D., Curtin, N. A., Kawar, S. L., Patel, K. & Dickson, G. 2009 In : Rejuvenation Research. 12, 2, p. 85-94 10 p.

    Research output: Contribution to journalArticle

  103. Published

    Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1

    Benlahrech, A., Harris, J., Meiser, A., Papagatsias, T., Hornig, J., Hayes, P., Lieber, A., Athanasopoulos, T., Bachy, V., Csomor, E., Daniels, R., Fisher, K., Gotch, F., Seymour, L., Logan, K., Barbagallo, R., Klavinskis, L., Dickson, G. & Patterson, S. 2009 In : Proceedings of the National Academy of Sciences of the United States of America. 106, 47, p. 19940-5 6 p.

    Research output: Contribution to journalArticle

  104. Published

    Bacillus probiotics

    P.H, V., Dong, T. C. & Cutting, S. 2009 In : Nutrafoods. p. 7-14 7 p., 8

    Research output: Contribution to journalArticle